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Chlorine dioxide
go.drugbank.com/drugs/DB12453ApprovedChlorine Dioxide has been used in trials studying the treatment of Halitosis.
Products: Disinfectant and Sanitizer, V Shield Hand SanitizerTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigationalTafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives[A27206] developed by FoldRX.[A189717] Tafamidis is structurally similar to diflusinal. … [A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: VYNDAQEL SOFT GELATIN CAPSULE 20MGMaraviroc
go.drugbank.com/drugs/DB04835ApprovedInvestigationalIt was originally labelled as UK-427857 during development but was assigned the Maraviroc name as it entered trials. It was approved for use by the FDA in August, 2007. … interaction between HIV and CCR5.
Products: Celsentri Film-Coated Tablet 150mgBetaxolol
go.drugbank.com/drugs/DB00195ApprovedInvestigationalA cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Categories: Antiglaucoma Preparations and MioticsProducts: KERLONE 20MG, BETAC 20MG TABLETSEptinezumab
go.drugbank.com/drugs/DB14040ApprovedInvestigationalEptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (_Pichia pastoris_) and developed by Lundbeck Seattle Biopharmaceuticals. … [L12318] Eptinezumab has been specifically designed to bind to both alpha and beta forms of the human calcitonin gene-related peptide (CGRP).
Categories: Amino Acids, Peptides, and ProteinsProducts: VYEPTI CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/MLMultifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
go.drugbank.com/bio_entities/BE0002195TargetEnzymeHumansCatalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:25419660). … Essential for normal biosynthesis and secretion of type IV collagens (Probable) (PubMed:18834968). Essential for normal formation of basement membranes (By similarity)
Polypeptides: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3Disintegrin and metalloproteinase domain-containing protein 9
go.drugbank.com/bio_entities/BE0003412TargetHumansMetalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. … May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 9Sodium- and chloride-dependent GABA transporter 3
go.drugbank.com/bio_entities/BE0004733TargetHumansCan also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity) … Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).
Polypeptides: Sodium- and chloride-dependent GABA transporter 3Disintegrin and metalloproteinase domain-containing protein 33
go.drugbank.com/bio_entities/BE0019245TargetHumansMetalloprotease that cleaves and sheds the ectodomains of cell-surface proteins and thereby contributes to angiogenesis, cell differentiation, inflammation, and cell proliferation (PubMed:14676211, PubMed … Promotes and maintains a proliferative phenotype in vascular smooth muscle cells through regulation of the PI3K/AKT and ERK signaling pathways (PubMed:33982767).
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 33Urea C-13
go.drugbank.com/drugs/DB09510ApprovedInvestigationalIf gastric urease from H. pylori is present, urea is split to form CO2 and NH3 at the interface between the gastric epithelium and lumen and 13CO2 is absorbed into the blood and exhaled in the breath. … To detect H. pylori, urea labeled with 13C is swallowed by the patient.
Products: UBIT Tablet 100mg