Search
Aldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalGenetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene.
Synonyms: ILT-101, 125-L-Serine-2-133-interleukin 2Products: Proleukin 18 x 10 6 IE - Pulver zur Herstellung einer Injektions- oder Infusionslösung, PROLEUKIN 18X106 IU/ML STERİL IV LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADETRufinamide
go.drugbank.com/drugs/DB06201ApprovedRufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Categories: Heterocyclic Compounds, 1-RingProducts: INOVELON FILM-COATED TABLET 200 MG, Inovelon 200 mg film-coated tabletsTucatinib
go.drugbank.com/drugs/DB11652ApprovedInvestigationalIt was developed by Seattle Genetics and approved by the FDA on April 17, 2020. … Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast cancer.
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: TUKYSA 50 mg film-coated tablets, TUKYSA (TUCATINIB) FILM-COATED TABLETS 50 mgProteasome subunit beta type-10
go.drugbank.com/bio_entities/BE0004738TargetHumansThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-depe...
Polypeptides: Proteasome subunit beta type-10Synonyms: Low molecular mass protein 10Keratin, type I cytoskeletal 10
go.drugbank.com/bio_entities/BE0009062TargetHumansStructural component of intermediate filaments in suprabasal keratinocytes of stratified epithelia. Forms heteropolymers primarily with the type II keratin KRT1, and also with KRT2, assembling into intermediate filament networks that sup...
Polypeptides: Keratin, type I cytoskeletal 10Synonyms: CK-10, Keratin-10Serine/threonine-protein kinase 10
go.drugbank.com/bio_entities/BE0009541TargetHumansSerine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a neg...
Polypeptides: Serine/threonine-protein kinase 10Interleukin-10 receptor subunit beta
go.drugbank.com/bio_entities/BE0014312TargetHumansShared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. ...
Polypeptides: Interleukin-10 receptor subunit betaSynonyms: IL-10 receptor subunit beta, Interleukin-10 receptor subunit 2Mitogen-activated protein kinase 10
go.drugbank.com/bio_entities/BE0001097TargetHumansSerine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the...
Polypeptides: Mitogen-activated protein kinase 10Synonyms: MAPK 10, MAP kinase 10Carbonic anhydrase-related protein 10
go.drugbank.com/bio_entities/BE0003631TargetHumansDoes not have a catalytic activity
Polypeptides: Carbonic anhydrase-related protein 10Antilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalEquine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune s...
Categories: Immunoglobulin GProducts: ATGAM INJECTION 50 mg/ml, EQUAGAM 50 MG/ML İNFÜZYONLUK ÇÖZELTİ İÇEREN KONSANTRESİ, 5 ADET