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Salicylic Acid Action Pathway
smpdb.ca/view/SMP0000709Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … It can be used to reduce pain and fever. Salicylic acid can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Salicylic acid · Calcium · Magnesium cation +5 moreLysophosphatidic Acid LPA5 Signalling
smpdb.ca/view/SMP0063757SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 5Lysophosphatidic Acid LPA6 Signalling
smpdb.ca/view/SMP0063759SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 6Clorazepic Acid Action Pathway
smpdb.ca/view/SMP0126122Drug actionClorazepic acid or clorazepate is a benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal. … Some side effects of using clorazepic acid may include dizziness, nervousness, blurred vision, and headache.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Clorazepic acid · Calcium · Magnesium cation +4 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Clodronic Acid Action Pathway
smpdb.ca/view/SMP0126307Drug actionClodronic acid is a bisphosphonate used for the treatment of osteoporosis in women experiencing menopause, hypercalcemia malignancy and osteolysis. … It can be managed through monitoring as hypocalcemia can present itself prior to the overdose, and specializing care via the administration of electrolytes.
Drugs: ATP · Clodronic acid · Magnesium cation · Dimethylallyl Diphosphate · Geranyl Diphosphate · Pyrophosphoric acid +3 moreEtidronic Acid Action Pathway
smpdb.ca/view/SMP0126349Drug actionEtidronic acid binds to hydroxylapatite and during bone resorption, it is released and taken up into the osteoclast by endocytosis. … Once absorbed etidronic acid is then transported into the cytosol, where it then goes to the mitochondrial matrix to inhibit ADP/ATP translocase.
Drugs: ATP · Etidronic acid · Magnesium cation · Dimethylallyl Diphosphate · Geranyl Diphosphate · Pyrophosphoric acid +3 moreTiludronic Acid Action Pathway
smpdb.ca/view/SMP0126351Drug actionTiludronic acid is a first-generation bisphosphonate used to treat Paget's disease, similar to etidronic acid and clodronic acid. … Tiludronic acid has a structure similar to pyrophosphate and due to this can be incorporated into ATP analogues that cannot be hydrolyzed.
Drugs: ATP · Tiludronic acid · Magnesium cation · Dimethylallyl Diphosphate · Geranyl Diphosphate · Pyrophosphoric acid +3 moreMethylphosphinic Acid Action Pathway
smpdb.ca/view/SMP0126733Drug actionMethylphosphinic acid is an experimental drug being tested to be a possible cholinesterase inhibitor, as it appears to inhibit the breakdown of acetylcholine. … Further research needs to be conducted in order to confirm results, safety and confirm the mechanism of action.
Oxidronic acid Drug Metabolism
smpdb.ca/view/SMP0130675MetabolicOxidronic acid passes through the liver and is then excreted from the body mainly through the kidney. … Oxidronic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Oxidronic acidEthacrynic Acid Diuretic Action Pathway
smpdb.ca/view/SMP0124515Drug actionEthacrynic acid binds to NKCC2 transporter and inhibits it, preventing Na+, K+ and Cl- reabsorption from the lumen. … Ethacrynic acid is a loop diuretic drug, administered orally or intravenously to treat high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.