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Displaying results 131 - 140 of 296 in total
  1. Target

    Potassium channel subfamily T member 1

    go.drugbank.com/bio_entities/BE0015369
    TargetHumans

    Sodium-activated K(+) channel (PubMed:37494189). Acts as an important mediator of neuronal membrane excitability (PubMed:37494189). Contributes to the delayed outward currents (By similarity). … Contributes to synaptic development and plasticity (By similarity)

    Synonyms: Sodium and chloride-activated ATP-sensitive potassium channel Slo2.2
  2. Target

    Potassium channel subfamily T member 2

    go.drugbank.com/bio_entities/BE0015626
    TargetHumans

    Sodium-activated and chloride-activated potassium channel (PubMed:14684870, PubMed:16687497, PubMed:25214519, PubMed:27682982, PubMed:29069600, PubMed:29740868).

    Synonyms: Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1, Sequence like an intermediate conductance potassium channel subunit
  3. Target

    Na(+)/citrate cotransporter

    go.drugbank.com/bio_entities/BE0008677
    TransporterHumans

    High-affinity sodium/citrate cotransporter that mediates the entry of citrate into cells, which is a critical participant of biochemical pathways (PubMed:12445824, PubMed:12826022, PubMed:26324167, PubMed … May function in various metabolic processes in which citrate has a critical role such as energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis (PubMed

    Synonyms: Sodium-coupled citrate transporter, Sodium-dependent citrate transporter
  4. Target

    Inorganic pyrophosphatase

    go.drugbank.com/bio_entities/BE0003737
    TargetBurkholderia pseudomallei (strain 1710b)

    Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.

    Polypeptides: Inorganic pyrophosphataseSynonyms: Pyrophosphate phospho-hydrolase
  5. Target

    Solute carrier family 4 member 11

    go.drugbank.com/bio_entities/BE0017156
    TransporterHumans

    Multifunctional transporter with an impact in cell morphology and differentiation. … At early stages of stem cell differentiation, participates in synergy with ITGA5-ITGB1 and ITGAV-ITGB3 integrins and BMPR1A to promote cell adhesion and contractility that drives differentiation toward

    Synonyms: Sodium borate cotransporter 1
  6. Target

    Excitatory amino acid transporter 3

    go.drugbank.com/bio_entities/BE0001054
    TargetTransporterHumans

    Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:21123949, PubMed:26690923, PubMed:33658209, PubMed:7521911, PubMed … Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (PubMed:21123949).

    Synonyms: Neuronal and epithelial glutamate transporter, Sodium-dependent glutamate/aspartate transporter 3
  7. Target

    Pendrin

    go.drugbank.com/bio_entities/BE0009874
    TransporterHumans

    Sodium-independent transporter of chloride and iodide (PubMed:10192399, PubMed:11932316, PubMed:12107249, PubMed:16684826, PubMed:24051746). … Mediates electroneutral chloride-bicarbonate, chloride-iodide and chloride-formate exchange with 1:1 stoichiometry (PubMed:10644529, PubMed:15155570, PubMed:24051746, PubMed:35601831).

    Synonyms: Sodium-independent chloride/iodide transporter
  8. Target

    Solute carrier family 13 member 1

    go.drugbank.com/bio_entities/BE0000022
    TransporterHumans

    Can also mediate the transport of selenate and thiosulfate (By similarity) … Sodium:sulfate symporter that mediates sulfate reabsorption in the kidney and small intestine (PubMed:11161786, PubMed:38552027, PubMed:39576865).

    Synonyms: Renal sodium/sulfate cotransporter
  9. Target

    Solute carrier family 13 member 2

    go.drugbank.com/bio_entities/BE0000447
    TransporterHumans

    Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small … intestine and renal proximal tubule (PubMed:10894787, PubMed:8967342, PubMed:9668069, PubMed:38552027).

    Synonyms: Renal sodium/dicarboxylate cotransporter
  10. Target

    Excitatory amino acid transporter 4

    go.drugbank.com/bio_entities/BE0002270
    TargetHumans

    Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:26690923, PubMed:7791878). … Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:7791878).

    Synonyms: Sodium-dependent glutamate/aspartate transporter