Search

Displaying results 131 - 140 of 2517 in total
  1. Target

    Baculoviral IAP repeat-containing protein 1

    go.drugbank.com/bio_entities/BE0010810
    TargetHumans

    Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasi...

    Polypeptides: Baculoviral IAP repeat-containing protein 1
  2. Drug

    Octasulfur

    go.drugbank.com/drugs/DB09353
    Approved

    Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is...

    Products: Pharmassist Clarifex Ph Mud Crm 3.0%
  3. Drug

    Amfecloral

    go.drugbank.com/drugs/DB08924
    Experimental

    Amfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes. … This would produce an effect similar to the amphetamine/barbiturate combinations previously used in psychiatric medications.

  4. Drug

    Famprofazone

    go.drugbank.com/drugs/DB16702
    Experimental

    [L34724] It is important to note that the drug is metabolized to [methamphetamine] and [amphetamine] in the body and can lead to positive tests results for illicit drug use.

    Categories: Amphetamines
  5. Indication

    Narcolepsy

    go.drugbank.com/conditions/DBCOND0017525
    Drugs: Amphetamine · Armodafinil · Dextroamphetamine · Ephedrine · Metamfetamine · Methylphenidate +1 more
  6. Drug

    Vurolenatide

    go.drugbank.com/drugs/DB18440
    Investigational

    Vurolenatide is a recombinant fusion protein comprising exenatide and XTEN.

    Synonyms: GLP-1-XTEN, XTEN-GLP1
  7. Drug

    Cathinone

    go.drugbank.com/drugs/DB01560
    ExperimentalIllicit

    Cathinone differs from many other amphetamines in that its structure is a ketone. … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to the stimulant effect of Catha edulis.

  8. Drug

    Pembrolizumab

    go.drugbank.com/drugs/DB09037
    ApprovedInvestigational

    Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  9. Drug

    Propofol

    go.drugbank.com/drugs/DB00818
    ApprovedInvestigationalVet approved

    Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medic...

    Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: PROPOFOL-PF %1 200 MG/20 ML I.V. ENJEKSİYONLUK/İNFÜZYONLUK EMÜLSİYON, 5 ADET
  10. Drug

    Metoclopramide

    go.drugbank.com/drugs/DB01233
    ApprovedInvestigational

    Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat...

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: PP-METOCLOPRAMIDE TABLET