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Clofedanol
go.drugbank.com/drugs/DB04837ApprovedWithdrawnClofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Mixtures: Poly Hist PDPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalA colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Mixtures: Lubricant PM, retaine PMDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigationalDextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethor...
Mixtures: P-Tuss DM, Cold PECategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesRO7284755
go.drugbank.com/drugs/DB17527InvestigationalRO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein.
Zolazepam
go.drugbank.com/drugs/DB11555ExperimentalVet approvedIt is around four times the potency of diazepam but it is both water-soluble and un-ionized at physiological pH meaning that its onset is very fast.
Zinc chloride
go.drugbank.com/drugs/DB14533ApprovedZinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Mixtures: PM Toothache Relief, Orajel 4X Medicated PM For Toothache and GumD-Methionine
go.drugbank.com/drugs/DB02893ApprovedMixtures: NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino AcidsAncremonam
go.drugbank.com/drugs/DB19710InvestigationalAncremonam is under investigation in clinical trial NCT03377426 (LYS228 PK, Clinical Response, Safety and Tolerability in Patients With Complicated Urinary Tract Infection (cUTI)).
Ledaborbactam etzadroxil
go.drugbank.com/drugs/DB21455InvestigationalLedaborbactam etzadroxil is under investigation in clinical trial NCT06733675 (Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination).
Zanubrutinib
go.drugbank.com/drugs/DB15035ApprovedInvestigationalZanubrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Mantle cell lymphoma is an aggressive mature B-cell n...
Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates