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Displaying results 1471 - 1480 of 10000 in total
  1. Drug

    Pipemidic acid

    go.drugbank.com/drugs/DB13823
    Investigational

    Pipemidic acid is a quinolone antibacterial agent with activity against various gram-positive and gram-negative bacteria.[A275138, A275143]

    Products: ACIDO PIPEMIDICO DR. REDDY'S
  2. Target

    Cell growth-regulating nucleolar protein

    go.drugbank.com/bio_entities/BE0008958
    TargetMouse

    Prevents NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (PubMed:19489080). … In addition, inhibits NF-kappa-B-mediated expression of pro-inflammatory cytokines (By similarity).

    Synonyms: Protein expressed in male leptotene and zygotene spermatocytes 264
  3. Target

    Serine/threonine-protein kinase Nek3

    go.drugbank.com/bio_entities/BE0009497
    TargetHumans

    Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. … Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2

    Synonyms: Never in mitosis A-related kinase 3
  4. Indication

    Back pain

    go.drugbank.com/conditions/DBCOND0115953
    Drugs: Acetaminophen · Borneol · Camphor · Capsaicin · Choline salicylate · Chondroitin sulfate +11 more
    Synonyms: Pain in back
  5. Drug

    Octocrylene

    go.drugbank.com/drugs/DB09535
    Approved

    Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. … Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than

    Mixtures: Cle De Peau Beaute Gentle Protective I, Cle De Peau Beaute Gentle Protective IProducts: Scarsystem Scar Gel
  6. Drug

    L-arginine

    go.drugbank.com/drugs/DB17289
    ApprovedInvestigationalNutraceutical

    Mixtures: Amino Acid InJ.W.elecw.25%dex, 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
  7. Drug

    Pentoxyverine

    go.drugbank.com/drugs/DB11186
    ApprovedWithdrawn

    It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160]. … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate.

    Mixtures: Exall D, Zotex-D
  8. Drug

    Silicon

    go.drugbank.com/drugs/DB12982
    Approved

    Silicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or … Stage II Mycosis Fungoides).

    Mixtures: Procosa II, Calcium With Mg Zn Mn Cu CR Si and Vit. C & D
  9. Target

    Inactive phospholipase C-like protein 1

    go.drugbank.com/bio_entities/BE0001081
    TargetHumans

    Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). … Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.

    Synonyms: Phospholipase C-deleted in lung carcinoma
  10. Target

    Gremlin-1

    go.drugbank.com/bio_entities/BE0011799
    TargetHumans

    Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). … Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback

    Synonyms: Increased in high glucose protein 2, Down-regulated in Mos-transformed cells protein