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Displaying results 141 - 150 of 561 in total
  1. Target

    Peflin

    go.drugbank.com/bio_entities/BE0008696
    TargetHumans

    Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. … Other reports show that PEF1 dissociates from PDCD6 in presence of calcium, and may act as a negative regulator of PDCD6 (PubMed:11278427).

    Function: calcium ion binding
  2. Target

    Calsequestrin-1

    go.drugbank.com/bio_entities/BE0008699
    TargetHumans

    Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244). … Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction.

    Function: calcium ion binding
  3. Target

    Fibrillin-3

    go.drugbank.com/bio_entities/BE0008702
    TargetHumans

    Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles.

    Function: calcium ion binding
  4. Target

    Grancalcin

    go.drugbank.com/bio_entities/BE0008703
    TargetHumans

    Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions

    Function: calcium ion binding
  5. Target

    Cation channel sperm-associated protein 1

    go.drugbank.com/bio_entities/BE0008714
    TransporterTargetHumans

    Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization

    Function: calcium-activated cation channel activity
  6. Target

    Annexin A4

    go.drugbank.com/bio_entities/BE0008969
    TargetHumans

    Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis

    Function: calcium ion binding
  7. Target

    C-type lectin domain family 4 member E

    go.drugbank.com/bio_entities/BE0009096
    TargetHumans

    Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: recognizes damage-associated molecular patterns (DAMPs) of abnormal self and pathogen-associated

    Function: calcium ion binding
  8. Target

    Transient receptor potential cation channel subfamily V member 2

    go.drugbank.com/bio_entities/BE0009158
    TargetHumans

    Calcium-permeable, non-selective cation channel (PubMed:10201375). Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator.

    Function: calcium channel activity
  9. Target

    L-selectin

    go.drugbank.com/bio_entities/BE0010361
    TargetHumans

    Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325).

    Function: calcium ion binding
  10. Target

    Transmembrane channel-like protein 1

    go.drugbank.com/bio_entities/BE0017493
    TargetHumans

    TMC1 MET channel is highly permeable to calcium and likely transports monovalent cations (By similarity). Also involved in vestibular hair cells transduction current (By similarity)

    Function: calcium channel activity