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Displaying results 141 - 150 of 4018 in total
  1. Target

    T-box transcription factor T

    go.drugbank.com/bio_entities/BE0011656
    TargetHumans

    Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site

    Polypeptides: T-box transcription factor T
  2. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability. G...

    Products: REFOBACIN BONE CEMENT R
  3. Indication

    Bone Giant Cell Tumor

    go.drugbank.com/conditions/DBCOND0112909
    Drugs: Denosumab
    Synonyms: Bone giant cell tumour, Giant Cell Tumors of Bone
  4. Indication

    Bone Marrow Transplant Rejection

    go.drugbank.com/conditions/DBCOND0030791
    Drugs: Cyclosporine
    Synonyms: Rejection of bone marrow graft, Bone Marrow Transplant Rejection
  5. Indication

    Bone and Joint Infections

    go.drugbank.com/conditions/DBCOND0051086
    Drugs: Amikacin · Amoxicillin · Aztreonam · Cefoperazone · Cefotetan · Cefoxitin +10 more
    Synonyms: Bone and joint infection, Bone and Joint Infections
  6. Indication

    Bone and tooth decay

    go.drugbank.com/conditions/DBCOND0134714
    Drugs: Calcium gluconate
    Synonyms: Bone and tooth decay
  7. Drug

    Fluoride ion F-18

    go.drugbank.com/drugs/DB09398
    ApprovedInvestigational

    Its primary indication is for bone imaging. … Increased deposition around joints can occur in arthritis and following trauma and increased deposition in bone has been noted around fracture sites, in osteomyelitis, fibrous dysplasia, spondylitis tuberculosa

    Synonyms: Fluoride ion F-18
  8. Drug

    Mirvetuximab soravtansine

    go.drugbank.com/drugs/DB12489
    ApprovedInvestigational

    [L43967,L43972] It was subsequently granted full approval in March 2024.[L50306] In October 2024, it was approved in the EU for the same indication. [L52640] … breast and non-small-cell lung cancers.

  9. Drug

    Burosumab

    go.drugbank.com/drugs/DB14012
    ApprovedInvestigational

    It causes impaired bone growth and development in children and adolescents and issues with bone mineralization throughout a patient’s life [L2346]. … Most children with XLH suffer from bowed or bent legs, short stature, bone pain and severe dental pain.

    Categories: Drugs for Treatment of Bone Diseases, Drugs Affecting Bone Structure and Mineralization
  10. Drug

    Abaloparatide

    go.drugbank.com/drugs/DB05084
    ApprovedInvestigational

    [A256778] Abaloparatide is an osteoanabolic agent that stimulates bone formation. … [L740] It was first approved by the FDA on April 28, 2017,[A256748] for the treatment of osteoporosis in postmenopausal women and is also used to increase bone density in men with osteoporosis.

    Categories: Bone Density Conservation Agents