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Displaying results 1561 - 1570 of 1709 in total
  1. Target

    P2 Purinoceptors

    go.drugbank.com/bio_entities/BE0009827
    Target

    Putative receptor for purines coupled to G proteins … Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system

    Polypeptides: Lysophosphatidic acid receptor 4, Lysophosphatidic acid receptor 6Synonyms: LPA receptor 4, LPA receptor 6
  2. Target

    P2X purinoceptor 4

    go.drugbank.com/bio_entities/BE0005793
    TargetHumans

    Promotes the differentiation and activation of Th17 cells via expression of retinoic acid-related orphan receptor C/RORC (PubMed:35165166).

    Synonyms: ATP receptor, Purinergic receptor
  3. Target

    P2Y purinoceptor 1

    go.drugbank.com/bio_entities/BE0009816
    TargetHumans

    Receptor for extracellular adenine nucleotides such as ADP (PubMed:25822790, PubMed:9038354, PubMed:9442040).

    Synonyms: ADP receptor, Purinergic receptorFunction: A1 adenosine receptor binding
  4. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    [L6037] CADDRA recommends the use of methylphenidate due to long term studies, of over twenty years in duration, which show methylphenidate is safe and effective. … Water then permeates through the membrane into the tablet core where the osmotically active polymer excipients expand, allowing methylphenidate to release slowly through the orifice over a period of 6-

  5. Drug

    AP5280

    go.drugbank.com/drugs/DB05112
    Experimental

    AP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic designed to increase the therapeutic index relative to conventional, small-molecule platinum agents.

  6. Drug

    Dimethicone

    go.drugbank.com/drugs/DB11074
    ApprovedInvestigational

    Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food produc...

    Mixtures: CareCella Velvet Cover BB Cream, TONYMOLY Timeless Carat Foun Cover 01 Skin BeigeProducts: Cover Perfection Ideal Concealer Duo 02 Rich Beige, Cover Perfection Ideal Concealer Duo 01 Clear Beige
  7. Drug

    Efonidipine

    go.drugbank.com/drugs/DB09235
    Investigational

    Efonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to ...

  8. Drug

    SVV-001

    go.drugbank.com/drugs/DB06129
    Investigational

    SVV-001 has also demonstrated cancer-killing specificity 10,000 times higher than that of traditional chemotherapeutics with no overt toxicity at doses one million times higher than effective doses in

  9. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and h...

  10. Target

    Cubilin

    go.drugbank.com/bio_entities/BE0000936
    TargetTransporterHumans

    Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake (PubMed:10371504, PubMed:11606717, PubMed:11717447, PubMed:14576052, PubMed:9572993).

    Synonyms: 460 kDa receptor, Intestinal intrinsic factor receptor