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Displaying results 1571 - 1580 of 10000 in total
  1. Drug

    Catumaxomab

    go.drugbank.com/drugs/DB06607
    ApprovedWithdrawn

    Catumaxumab was approved for market in Canada in May 2012 for the same condition [FDA Label]. It is currently available under the brand name Removab. … Catumaxumab is a trifunctional monoclonal antibody developed for use in cancer treatment. It has affinity for T-cells, accessory immune cells, and cancer cells.

  2. Target

    Hyaluronan mediated motility receptor

    go.drugbank.com/bio_entities/BE0004702
    TargetHumans

    Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. … May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity)

    Synonyms: Receptor for hyaluronan-mediated motility
  3. Target

    Calcium-dependent secretion activator 1

    go.drugbank.com/bio_entities/BE0008704
    TargetHumans

    Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. … Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs.

    Synonyms: Calcium-dependent activator protein for secretion 1
  4. Indication

    Cognitive Impairment (CI)

    go.drugbank.com/conditions/DBCOND0138824
    Drugs: Piracetam
    Synonyms: Disturbance in cognition
  5. Indication

    Relapsed Acute Myelogenous Leukemia (AML)

    go.drugbank.com/conditions/DBCOND0069493
    Drugs: Enasidenib · Gemtuzumab ozogamicin · Ivosidenib · Olutasidenib · Revumenib · Ziftomenib
    Synonyms: Acute Myelogenous Leukemia in Relapse
  6. Drug

    (R)-carnitinyl-CoA betaine

    go.drugbank.com/drugs/DB02516
    Experimental

    Synonyms: R-carnitinyl-CoA inner salt, (R)-carnitinyl-CoA βine
  7. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    in recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and … [A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and

    Mixtures: CO-DEGREGANProducts: Rbx-clopidogrel
  8. Drug

    Dipropylene glycol

    go.drugbank.com/drugs/DB14140
    Investigational

    Products: Abelia pomegranate bounce up mask
  9. Indication

    Sleeping Disorders

    go.drugbank.com/conditions/DBCOND0148601
    Drugs: Amitriptyline · Cinolazepam · Delorazepam · Lormetazepam · Melperone · Mirtazapine +2 more
    Synonyms: Disturbance in sleep behavior, NOS, Disturbance in sleep behavior (finding)
  10. Target

    Nitric oxide synthase, inducible

    go.drugbank.com/bio_entities/BE0000005
    TargetEnzymeHumans

    In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). … Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7504305, PubMed:7531687, PubMed:7544004, PubMed:7682706).

    Synonyms: Inducible NO synthase