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Displaying results 151 - 160 of 561 in total
  1. Target

    Coagulation factor X

    go.drugbank.com/bio_entities/BE0000216
    TargetEnzymeHumans

    Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting (PubMed:22409427, PubMed:39880037).

    Function: calcium ion binding
  2. Target

    Vitamin K-dependent protein C

    go.drugbank.com/bio_entities/BE0000380
    TargetEnzymeHumans

    Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PubMed:25618265, PubMed:39880037

    Function: calcium ion binding
  3. Target

    Glutamate receptor ionotropic, NMDA 3B

    go.drugbank.com/bio_entities/BE0000534
    TargetHumans

    Component of a non-conventional N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with low calcium permeability and low voltage-dependent block

    Function: calcium channel activity
  4. Target

    C-reactive protein

    go.drugbank.com/bio_entities/BE0000877
    TargetHumans

    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine

    Function: calcium ion binding
  5. Target

    Calnexin

    go.drugbank.com/bio_entities/BE0001011
    TargetHumans

    Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum.

    Function: calcium ion binding
  6. Target

    Serum amyloid P-component

    go.drugbank.com/bio_entities/BE0001213
    TargetHumans

    May also function as a calcium-dependent lectin

    Function: calcium ion binding
  7. Target

    Inositol-trisphosphate 3-kinase A

    go.drugbank.com/bio_entities/BE0001627
    TargetHumans

    Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis

    Function: calcium/calmodulin-dependent protein kinase activity
  8. Target

    Synaptotagmin-2

    go.drugbank.com/bio_entities/BE0002138
    TargetHumans

    Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (By similarity).

    Function: calcium ion sensor activity
  9. Target

    Calcineurin subunit B type 2

    go.drugbank.com/bio_entities/BE0002143
    TargetHumans

    Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity

    Function: calcium ion binding
  10. Target

    Transient receptor potential cation channel subfamily V member 3

    go.drugbank.com/bio_entities/BE0003416
    TargetHumans

    Non-selective calcium permeant cation channel (PubMed:12077604, PubMed:12077606, PubMed:26818531, PubMed:37648856, PubMed:38691614).

    Function: calcium channel activity