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Displaying results 151 - 160 of 204 in total
  1. Target

    Pimeloyl-[acyl-carrier protein] methyl ester esterase

    go.drugbank.com/bio_entities/BE0001630
    TargetEnzymeEscherichia coli (strain K12)

    Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic acid into pimeloyl-CoA, a precursor in biotin biosynthesis. … The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.

    Polypeptides: Pimeloyl-[acyl-carrier protein] methyl ester esterase
  2. Target

    2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

    go.drugbank.com/bio_entities/BE0001617
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. … Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate

    Polypeptides: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseFunction: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
  3. Target

    2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

    go.drugbank.com/bio_entities/BE0001661
    TargetEscherichia coli (strain K12)

    Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

    Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseSynonyms: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
  4. Target

    2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

    go.drugbank.com/bio_entities/BE0001839
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

    Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseSynonyms: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
  5. Target

    Serine/threonine-protein kinase TAO3

    go.drugbank.com/bio_entities/BE0009393
    TargetHumans

    Promotes JNK signaling in hepatocytes and positively regulates hepatocyte lipid storage by inhibiting beta-oxidation and triacylglycerol secretion while enhancing lipid synthesis (PubMed:34634521). … Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade.

    Synonyms: Thousand and one amino acid protein 3
  6. Target

    Aurora kinase B

    go.drugbank.com/bio_entities/BE0003404
    TargetHumans

    The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly ( … histone H2A and enhancing binding and activity of the USP16 deubiquitinase at transcribed genes (By similarity).

    Synonyms: Aurora- and IPL1-like midbody-associated protein 1
  7. Target

    2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

    go.drugbank.com/bio_entities/BE0001303
    TargetShigella flexneri

    Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. … Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate

    Polypeptides: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseFunction: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
  8. Target

    D-galactose/methyl-galactoside binding periplasmic protein MglB

    go.drugbank.com/bio_entities/BE0003242
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    In addition, binds D-galactose and D-glucose and plays a role in the chemotaxis towards these two sugars by interacting with the Trg chemoreceptor (Probable). … Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import (By similarity).

    Polypeptides: D-galactose/methyl-galactoside binding periplasmic protein MglB
  9. Target

    2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

    go.drugbank.com/bio_entities/BE0004091
    TargetShewanella oneidensis (strain MR-1)

    Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. … Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate

    Polypeptides: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseFunction: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
  10. Target

    2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

    go.drugbank.com/bio_entities/BE0004142
    TargetMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

    Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. … Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate

    Polypeptides: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseFunction: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity