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Thrombin alfa
go.drugbank.com/drugs/DB11572ApprovedThrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. … The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious agents.
Oxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalIt is often used as first-line therapy for OAB.[A185990] … efficacy since initial FDA approval in 1975.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolateTamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension. … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.
Synonyms: (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide, (R)-(−)-tamsulosinInternational brands: Harnal DThyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831] Thyroid extract is no longer considered a first line therapy as it delivers a dose that is inconsistent with the stated strength of the tablet. … [A190813] Currently, patients are more likely to be treated with [levothyroxine].[A190813] Thyroid extracts were never FDA approved as their use in the United States predates the FDA.[A190831]
Levodopa
go.drugbank.com/drugs/DB01235ApprovedInvestigationalLevodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after … Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label].
Mixtures: LEV/CAR/EN AL100/25/200, LEV/CAR/EN AL200/50/200Synonyms: 3-Hydroxy-L-tyrosine, (−)-3-(3,4-dihydroxyphenyl)-L-alanineProcaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedIt is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. … This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection of penicillin. It is widely used in veterinary settings.
Mixtures: SENCAIN-S 100.000 IU/300.000 IU IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPUL, PENCAIN K-800 İ.Ü. IM ENJEKTABL FLAKON, 1 FLAKON + 1 AMPULCategories: Penicillin G, Heterocyclic Compounds, 2-RingEpcoritamab
go.drugbank.com/drugs/DB16672ApprovedInvestigational[L46516,L46556] In September 2023, epcoritamab was also approved in the EU for the same indication. … [L46516] It is administered subcutaneously and is currently being evaluated as a monotherapy and in combination for the treatment of a variety of hematologic malignancies.
Categories: Bispecific CD20-directed CD3 T Cell EngagerProducts: Tepkinly 4 mg/0,8 ml Enjeksiyonluk Çözelti (1 adet), Tepkinly 48 mg Enjeksiyonluk Çözelti (1 adet)Narcolepsy
go.drugbank.com/conditions/DBCOND0017525Drugs: Amphetamine · Armodafinil · Dextroamphetamine · Ephedrine · Metamfetamine · Methylphenidate +1 moreGelatin
go.drugbank.com/drugs/DB11242ApprovedInvestigationalVet approvedWithdrawnGelatin is a multifunctional ingredient that is used in foods, pharmaceuticals, cosmetics, and photographic films as a gelling agent, stabilizer, thickener, emulsifier, as well as film former. … [A32432] Interestingly, horse gelatin has been studied and it was found that in the horse, gelatin influences the homeostasis of the amino acids required for cartilage synthesis [A32434].
Mixtures: GELOFUSINE IN 500ML PLASTIC CONTAINER, GELOFUSINE IN 1000ML PLASTIC CONTAINER.Products: INFUSOL SG (SUCCINYLATED GELATIN (Bovine) INTRAVENOUS INFUSION 4% w/v), GELAFUNDIN 4Evening primrose oil
go.drugbank.com/drugs/DB11358ApprovedNutraceuticalIn its composition it presents some fatty acids such as [DB00132] and [DB13854]. … [L2845] By Health Canada, evening primrose oil is approved in over-the-counter combination dietary supplements.[L1113] By the EMA, evening primrose oil is approved in herbal preparations.[L2851]
Mixtures: PRIM E CAPSULE, Evening Primrose Oil With Vitamin ECategories: Fatty Acids, Omega-6, Cytochrome P-450 CYP2C19 Inhibitors