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Displaying results 1641 - 1650 of 10000 in total
  1. Indication

    HIV Wasting Syndrome

    go.drugbank.com/conditions/DBCOND0000270
    Drugs: Somatotropin
    Synonyms: HIV disease resulting in wasting syndrome
  2. Drug

    Odevixibat

    go.drugbank.com/drugs/DB16261
    ApprovedInvestigational

    [A236808,L34793] Odevixibat is the first approved non-surgical treatment option for PFIC.[L34803] Previous therapies for PFIC included a bile acid sequestrant such as [ursodeoxycholic acid]. … Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC

  3. Drug

    Garetosmab

    go.drugbank.com/drugs/DB16379
    ApprovedInvestigational

    [L63940,L64047] It is the second therapy approved for FOP, following [palovarotene] (Sohonos), which was approved in 2023, and is the first FOP therapy shown to reduce clinician-assessed flare-ups. … [L63940] Garetosmab-grts was approved by the FDA on August 19, 2026 to reduce the number of new heterotopic ossification lesions and clinician-assessed flare-ups in adults with FOP.

  4. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    Based on this uncertainty, in 2009, the FDA ultimately rejected Cell Therapeutic's initial application for accelerated approval for pixantrone use in relapsed or refractory NHL. … Another phase III trial, PIX-R, is now ongoing to clarify pixantrones place in therapy. It will compare pixantrone efficacy to that of gemcitabine. [2]

    Categories: Topoisomerase II Inhibitors
  5. Target

    G protein-coupled bile acid receptor 1

    go.drugbank.com/bio_entities/BE0005788
    TargetHumans

    G protein-coupled receptor for bile acid (PubMed:12419312, PubMed:12524422, PubMed:32698187, PubMed:32747649, PubMed:35858343). … Involved in bile acid promoted GLP-1 secretion (By similarity)

    Synonyms: Membrane-type receptor for bile acids
  6. Drug

    Clotiazepam

    go.drugbank.com/drugs/DB01559
    ApprovedIllicit

    Clotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.

  7. Indication

    Psychophysiological Disorders

    go.drugbank.com/conditions/DBCOND0172355
    Drugs: Melperone
    Synonyms: Psychosomatic factor in physical condition, NOS, Psychosomatic factor in physical condition (finding)
  8. Drug

    Cetyl alcohol

    go.drugbank.com/drugs/DB09494
    Approved

    According to the FDA Code of Federal Regulations, cetyl alcohol is a safe synthetic fatty acid in food and in the synthesis of food components under the condition that it contain not less than 98 percent … Cetyl alcohol is present in a waxy white powder or flake form at room temperature, and is insoluble in water and soluble in alcohols and oils [A32209].

  9. Drug

    Cantharidin

    go.drugbank.com/drugs/DB12328
    ApprovedInvestigational

    [A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory gift during mating. … [A32892] Nevertheless, it gained its first FDA approval on Jul 21, 2023, under the brand name YCANTH™ by Verrica Pharmaceuticals for the treatment of molluscum contagiosum in adult and pediatric patients

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    (R)-Gossypol

    go.drugbank.com/drugs/DB17379
    Investigational

    (R)-Gossypol is the R-isomer of [Gossypol].

    Synonyms: Gossypol r-form, (R)-Gossypol