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Type II iodothyronine deiodinase
go.drugbank.com/bio_entities/BE0009855EnzymeTargetHumansPlays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:11108274, PubMed:10403186, PubMed:18821722
Synonyms: Type 2 DIBacterial hemoglobin
go.drugbank.com/bio_entities/BE0002903TargetVitreoscilla stercorariaThis protein functions as a terminal oxidase.
Synonyms: Soluble cytochrome OAzelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigationalallergic rhinitis in patients 6 years of age and older. … [L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996.
Mixtures: DYMISTA D, N-S-4Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesTriclocarban
go.drugbank.com/drugs/DB11155ApprovedIt is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. … In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products containing triclocarban due to negative health effects such as bacterial resistance or hormonal
Synonyms: N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea, 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)ureaProducts: DG Body Antibacterial Deodorant 3.5 oz bar, NEXT 1 Anti-bacterialRelapsed Acute Lymphoblastic Leukemia (ALL)
go.drugbank.com/conditions/DBCOND0069491Synonyms: Acute Lymphoblastic Leukemia, in RelapseHypochlorous acid
go.drugbank.com/drugs/DB14135InvestigationalAn oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Synonyms: Chlor(I)-säureMixtures: K-100, K-100Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigationalIn July 2024, it was further approved in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation therapy in newly diagnosed, transplant-eligible patients. … [A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind.
Categories: CD38 (Clusters of Differentiation 38) inhibitorsProducts: Darzalex IV, DARZALEX® SC 120 MG/ML SOLUCIÓN INYECTABLEHutchinson-Gilford Progeria Syndrome
go.drugbank.com/conditions/DBCOND0041142Drugs: LonafarnibSynonyms: Progeria, Progeria syndromeMeningioma of Brain
go.drugbank.com/conditions/DBCOND0169076Drugs: HydroxyureaSynonyms: Meningioma, benign, no ICD-O subtype, Meningioma, benign, no ICD-O subtype (morphologic abnormality)