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Stabilin-1
go.drugbank.com/bio_entities/BE0010944TargetHumansBinds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection.
Synonyms: Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1F-box/WD repeat-containing protein 1A
go.drugbank.com/bio_entities/BE0021224TargetHumansHas an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and PER2 (PubMed:15917222). … Ubiquitination of NFKBIA occurs at 'Lys-21' and 'Lys-22' (PubMed:10066435).
Synonyms: F-box and WD repeats protein beta-TrCPHydroxyacyl-coenzyme A dehydrogenase, mitochondrial
go.drugbank.com/bio_entities/BE0000377TargetHumansMitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10) (PubMed:10231530, PubMed:11489939 … Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion
Synonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenaseCytohesin-2
go.drugbank.com/bio_entities/BE0002654TargetHumansPromotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (By similarity).
Synonyms: PH, SEC7 and coiled-coil domain-containing protein 2Excitatory amino acid transporter 3
go.drugbank.com/bio_entities/BE0001054TargetTransporterHumansPlays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (PubMed:21123949). … Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:21123949, PubMed:26690923, PubMed:33658209, PubMed:7521911, PubMed
Synonyms: Neuronal and epithelial glutamate transporterRibosomal protein S6 kinase alpha-4
go.drugbank.com/bio_entities/BE0004614TargetHumans/FOS and c-jun/JUN. … Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and
Synonyms: Nuclear mitogen- and stress-activated protein kinase 2Zinc transporter ZIP12
go.drugbank.com/bio_entities/BE0009897TransporterHumansMay play a role in neurulation and neurite extension. … May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis
Synonyms: Zrt- and Irt-like protein 12Zinc transporter ZIP13
go.drugbank.com/bio_entities/BE0009900TransporterHumansFunctions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol (PubMed:21917916, PubMed:23213233).
Synonyms: Zrt- and Irt-like protein 13Leucine carboxyl methyltransferase 1
go.drugbank.com/bio_entities/BE0000450TargetHumansMethylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues
Synonyms: Protein-leucine O-methyltransferaseFunction: protein C-terminal carboxyl O-methyltransferase activityZinc transporter ZIP1
go.drugbank.com/bio_entities/BE0009902TransporterHumansTransporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space (PubMed:11301334, PubMed:12888280, PubMed:16844077). Functions as the major importer of zinc from circulating blood plasma into...
Synonyms: Zrt- and Irt-like protein 1