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Displaying results 161 - 170 of 2763 in total
  1. Target

    ActII protein

    go.drugbank.com/bio_entities/BE0004336
    TargetStreptomyces coelicolor

    TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (te...

    Polypeptides: ActII proteinSynonyms: SubName: ActII protein
  2. Target

    Protein farnesyltransferase subunit beta

    go.drugbank.com/bio_entities/BE0002372
    TargetHumans

    Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X

    Polypeptides: Protein farnesyltransferase subunit betaSynonyms: Ras proteins prenyltransferase subunit beta
  3. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0001257
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...

    Polypeptides: Protein RecA
  4. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0003084
    TargetShigella flexneri

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...

    Polypeptides: Protein RecA
  5. Target

    cAMP-dependent protein kinase catalytic subunit alpha

    go.drugbank.com/bio_entities/BE0003761
    TargetHumans

    Involved in the regulation of platelets in response to thrombin and collagen; maintains circulating platelets in a resting state by phosphorylating proteins in numerous platelet inhibitory pathways when

    Polypeptides: cAMP-dependent protein kinase catalytic subunit alphaSynonyms: PKA C-alpha
  6. Target

    Protein S100-A12

    go.drugbank.com/bio_entities/BE0001206
    TargetHumans

    S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.

    Polypeptides: Protein S100-A12Synonyms: Neutrophil S100 protein, S100 calcium-binding protein A12
  7. Target

    Protein SLC31A2

    go.drugbank.com/bio_entities/BE0003662
    TransporterHumans

    Does not function as a copper(1+) importer in vivo (By similarity). However, in vitro functions as a low-affinity copper(1+) importer (PubMed:17617060, PubMed:17944601). Regulator of SLC31A1 which facilitates the cleavage of the SLC31A1 ...

    Polypeptides: Protein SLC31A2
  8. Target

    Protein deacetylase HDAC6

    go.drugbank.com/bio_entities/BE0002368
    TargetHumans

    In addition to its protein deacetylase activity, plays a key role in the degradation of misfolded proteins: when misfolded proteins are too abundant to be degraded by the chaperone refolding system and … Deacetylates antiviral protein RIGI in the presence of viral mRNAs which is required for viral RNA detection by RIGI (By similarity).

    Polypeptides: Protein deacetylase HDAC6Synonyms: E3 ubiquitin-protein ligase HDAC6
  9. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0001269
    TargetMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...

    Polypeptides: Protein RecA
  10. Target

    Capsid scaffolding protein

    go.drugbank.com/bio_entities/BE0001959
    TargetHHV-4

    Capsid scaffolding protein Acts as a scaffold protein by binding major capsid protein in the cytoplasm, inducing the nuclear localization of both proteins. … Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein. Cleavages products are evicted from the capsid before or during DNA packaging.

    Polypeptides: Capsid scaffolding proteinSynonyms: Capsid protein P40, Protein EC-RF3/EC-RF3A