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Tolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedTolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinac...
Products: ProClearz Fungi-Cide PMSodium tartrate
go.drugbank.com/drugs/DB13707ApprovedWithdrawnIt acts as an emulsifier and pH control agent in food products [L2590].
Sodium carbonate
go.drugbank.com/drugs/DB09460ApprovedWithdrawnSodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide neutralizes gastric acid thereby ac...
Trolamine
go.drugbank.com/drugs/DB13747ApprovedInvestigationalIt is commonly used as a pH adjuster and surfactant in industrial and cosmetic products such as skin and hair conditioning products.
Benzoyl peroxide
go.drugbank.com/drugs/DB09096ApprovedInvestigationalBenzoyl peroxide is a commonly used drug in topical treatments for acne. It has been formulated as products with either a single active ingredient, or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond ...
Products: B P O COMBUSTIN GEL, PR Benzoyl Peroxide WashBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigationalBaloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation. It is a prodrug of baloxavir with an impro...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesDexamethasone
go.drugbank.com/drugs/DB01234ApprovedInvestigationalVet approvedDexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other condit...
Mixtures: Dex-Moxi PF, DexMoxiKetor PFCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsMitapivat
go.drugbank.com/drugs/DB16236ApprovedInvestigational[A245478] On February 17, 2022, the FDA approved mitapivat as the first disease-modifying treatment for hemolytic anemia in adults with pyruvate kinase (PK) deficiency, a rare, inherited disorder leading
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSildenafil
go.drugbank.com/drugs/DB00203ApprovedInvestigationalIn eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) . The result of doing so allows cGMP pre...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Pb-sildenafil, SILEREthanol
go.drugbank.com/drugs/DB00898ApprovedInvestigationalA clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in ...
Mixtures: iBrea Micro Silver Hand with Pure Silver, iBrea Micro Silver Hand with Pure SilverCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers