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Displaying results 1711 - 1720 of 2250 in total
  1. Target

    Serine/threonine-protein kinase mTOR

    go.drugbank.com/bio_entities/BE0002386
    TargetHumans

    The mTORC2 complex also phosphorylates various proteins involved in insulin signaling, such as FBXW8 and IGF2BP1 (By similarity). … The mTORC1 complex is inhibited in response to starvation and amino acid depletion (PubMed:12150925, PubMed:12150926, PubMed:24403073, PubMed:31695197).

    Synonyms: FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1
  2. Target

    Proteasome subunit beta type-2

    go.drugbank.com/bio_entities/BE0002349
    TargetHumans

    Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)

    Synonyms: Multicatalytic endopeptidase complex subunit C7-I
  3. Drug

    Hexetidine

    go.drugbank.com/drugs/DB08958
    ApprovedWithdrawn

    A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.

    Categories: Genito Urinary System and Sex HormonesInternational brands: Vagi-Hex
  4. Drug

    GFT14

    go.drugbank.com/drugs/DB05061
    Experimental

    GFT14 is destined to improve the condition of patients at risk from cardiovascular disease by a simultaneous and favorable action on the plasmatic lipids (rise of HDL- cholesterol et lowering of triglycerides

  5. Drug

    Sulthiame

    go.drugbank.com/drugs/DB08329
    Approved

    Categories: Genito Urinary System and Sex Hormones
  6. Drug

    Thyrotropin alfa

    go.drugbank.com/drugs/DB00024
    ApprovedInvestigationalVet approved

    Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in...

    Categories: Sex Hormones and Insulins
  7. Drug

    Coal tar

    go.drugbank.com/drugs/DB11082
    Approved

    Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.

    Mixtures: PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT, X-tar ShampooCategories: Complex Mixtures
  8. Drug

    Aflibercept

    go.drugbank.com/drugs/DB08885
    ApprovedInvestigational

    [L47976] An aflibercept biosimilar, Yesafili, was approved for use in the EU in September 2023.

  9. Drug

    Bevacizumab

    go.drugbank.com/drugs/DB00112
    ApprovedInvestigational

    [A286054] This off-label practice was formalized with the approval of Lytenava (bevacizumab-vikg in the US; bevacizumab gamma in the EU/UK), the first ophthalmic formulation of bevacizumab developed specifically

    Categories: Complex MixturesProducts: ABXEDA E
  10. Drug

    Phthalylsulfathiazole

    go.drugbank.com/drugs/DB13248
    Approved

    Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .

    Categories: Genito Urinary System and Sex Hormones