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Iopromide
go.drugbank.com/drugs/DB09156Approved[A225366] Although iopromide can cause several serious adverse effects, including cardiac events, thromboembolism, hypersensitivity reaction, and even death if administered intrathecally inadvertently, … it is still deemed to have a favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsHuman vaccinia virus immune globulin
go.drugbank.com/drugs/DB14112ApprovedInvestigationalHuman vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human product that is only available in very limited quantities - all factors that may intervene with
Methsuximide
go.drugbank.com/drugs/DB05246ApprovedMesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Oteracil
go.drugbank.com/drugs/DB03209ApprovedInvestigationalOteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells.
Dupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigationalIt is currently used to treat atopic dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and eosinophilic esophagitis. … [A180478] As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in
Products: DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml, DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14mlExagamglogene autotemcel
go.drugbank.com/drugs/DB15572ApprovedInvestigational[L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS. … [L49246] In January 2024, exagamglogene autotemcel received an additional FDA approval for the treatment of transfusion-dependent β-thalassemia.
Synonyms: a guide RNA (gRNA), from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting ofOuabain
go.drugbank.com/drugs/DB01092ApprovedIt is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase. … A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis.
Categories: Compounds used in a research, industrial, or household settingMisoprostol
go.drugbank.com/drugs/DB00929ApprovedInvestigational[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the … Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.
Mixtures: ARTHROTEC 75 MG TABLET, 20 ADET, DIFEMIS 50 MG/0.2 MG TABLET, 20 ADETProducts: CYTOTEC 200 MCG TABLET, 28 ADET, MISODEL 200 MCG VAJINAL SALIM SISTEMI ,1 ADETRelebactam
go.drugbank.com/drugs/DB12377ApprovedInvestigational[label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination product RecarbrioⓇ in July 2019.[L7568] … [A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge.