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Displaying results 1731 - 1740 of 10000 in total
  1. Drug

    Odesivimab

    go.drugbank.com/drugs/DB15900
    ApprovedInvestigational

    [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection. … [A222078] The chief surface target of EBOV particles is the GP<sub>1,2</sub> glycoprotein, which also appears on the surface of EBOV-infected cells, offering opportunities for both neutralizing and cytotoxic

    Categories: Treatments for Ebola Virus Disease
  2. Drug

    Islatravir

    go.drugbank.com/drugs/DB15653
    ApprovedInvestigational

    Islatravir is a first-in-class, highly potent nucleoside reverse transcriptase translocation inhibitor (NRTTI) used in combination therapy for the treatment of HIV-1 infection. … [L56141] This formulation represents a significant advance in long-acting oral therapy due to islatravir's exceptionally long intracellular half-life, which allows for extremely low dosing.

  3. Drug

    Fenyramidol

    go.drugbank.com/drugs/DB13414
    Investigational

    Products: CABRAL 800 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (3 AMPUL), PHEBDOL 800 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ, 3 ADET
  4. Indication

    Metastatic Malignant Neoplasm to the Leptomeninges

    go.drugbank.com/conditions/DBCOND0057483
    Drugs: Cytarabine
    Synonyms: Metastatic Malignant Neoplasm in the Leptomeninges
  5. Drug

    Dioxybenzone

    go.drugbank.com/drugs/DB11221
    ApprovedWithdrawn

    Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525]. … Dioxybenzone, or benzophenone-8, is an organic compound derived from [DB01878] that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays.

  6. Drug

    Silicon dioxide

    go.drugbank.com/drugs/DB11132
    Approved

    Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. In powdered food products and pharmaceutical tablets, silicon dioxide is added as a flow agent to absorb water. … Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2.

    Mixtures: Zenni Tooth for Sensitive Tooth, Exoden All In OneCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Etuvetidigene Autotemcel

    go.drugbank.com/drugs/DB17593
    ApprovedInvestigational

    [L54693] WAS is a rare X-linked disorder caused by a mutation in the gene encoding the WAS protein, leading to a compromised immune system. … [A274878] The WAS protein is expressed on non-erythroid hematopoietic cells and regulates the function of actin filaments in the cytoskeleton.[A274878]

  8. Drug

    Levoketoconazole

    go.drugbank.com/drugs/DB05667
    Approved

    It possesses most of the inhibitory effect towards steroidogenic enzymes, making it an attractive candidate for CS treatment with a potentially lower toxicity profile than its racemate. … changes in body composition, neuropsychiatric effects, changes in blood pressure and chemistry, and opportunistic infections.

    Categories: Corticosteroids for Systemic Use
  9. Pathway

    Multiple Carboxylase Deficiency, Neonatal or Early Onset Form

    smpdb.ca/view/SMP0125778
    Disease

    in the BTD gene or the HLCS gene. … The BTD gene encodes for biotinidase and the HLCS gene encodes for holocarboxylase synthetase.

    Drugs: Biotin · Lysine · ATP · Pyrophosphoric acid
  10. Drug

    Remestemcel-L

    go.drugbank.com/drugs/DB13973
    ApprovedInvestigationalWithdrawn

    It was approved for use in Canada in May 2012 as Prochymal for the management of refractory acute Graft versus Host Disease (aGvHD) in children who are unresponsive to systemic steroid therapies, with … Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion.