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Sulfapyridine
go.drugbank.com/drugs/DB00891ApprovedWithdrawnAntibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Categories: Sulfonamides and trimethoprim, Genito Urinary System and Sex HormonesSynonyms: N-2-Pyridylsulfanilamide, N(1)-PyridylsulfanilamideLecithin
go.drugbank.com/drugs/DB15834InvestigationalA complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines, and phosphatidylinositols.
Categories: Compounds used in a research, industrial, or household settingProducts: SAFWA HEALTH TRIPLE L LECITHIN 1000MG SOFTGEL CAPSULE, KORDEL`S LECITHIN 1200MG CAPSULELurasidone
go.drugbank.com/drugs/DB08815ApprovedInvestigationalLurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Products: LATUDA TABLET 20MG, Latuda Film-Coated Tablets 20mgLimaprost
go.drugbank.com/drugs/DB09211InvestigationalLimaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. … Prostaglandins have a wide variety of actions, including, but not limited to muscular constriction and mediation of inflammation.
Categories: Blood and Blood Forming OrgansProducts: OPALMON TABLETS 5 ugMetolazone
go.drugbank.com/drugs/DB00524ApprovedInvestigationalA quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Categories: Genito Urinary System and Sex Hormones, metolazone and potassium-sparing agentsProducts: Zaroxolyn Tab 10mgRifapentine
go.drugbank.com/drugs/DB01201ApprovedInvestigationalRifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. … Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Products: PRIFTIN FILM COATED TABLETS 150MGSodium- and chloride-dependent GABA transporter 1
go.drugbank.com/bio_entities/BE0000249TargetHumansCan also mediate sodium- and chloride-dependent transport of hypotaurine but to a much lower extent as compared to GABA (By similarity) … The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA (By similarity).
Polypeptides: Sodium- and chloride-dependent GABA transporter 1Sodium- and chloride-dependent creatine transporter 1
go.drugbank.com/bio_entities/BE0000375TargetTransporterHumansPlays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity)
Polypeptides: Sodium- and chloride-dependent creatine transporter 1Signal transducer and activator of transcription 5B
go.drugbank.com/bio_entities/BE0000891TargetHumansInvolved in the oncostatin-M-mediated signaling pathway through type II OSM receptor complex (heterodimers composed of OSMR and IL6ST) (PubMed:9188471) … Signal transducer and transcription activator that mediates cellular responses to cytokines, hormones and growth factors (PubMed:29844444, PubMed:9188471).
Polypeptides: Signal transducer and activator of transcription 5BDisintegrin and metalloproteinase domain-containing protein 10
go.drugbank.com/bio_entities/BE0002404TargetHumansCleaves TREM2, resulting in shedding of the TREM2 ectodomain (PubMed:24990881). Involved in the development and maturation of glomerular and coronary vasculature (By similarity). … Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity (PubMed:12475894).
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 10