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Displaying results 1741 - 1750 of 10000 in total
  1. Indication

    Otoferlin Gene-mediated Hearing Loss

    go.drugbank.com/conditions/DBCOND0170571
    Drugs: Lunsotogene parvec
    Synonyms: Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF)
  2. Drug

    Isoconazole

    go.drugbank.com/drugs/DB08943
    Approved

    Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.

    Mixtures: TİNAGEN 1 MG+10 MG/1 G DERİ KREMİ, 15 G, TRODERM 10 MG/G+1 MG/G KREM ,15 GCategories: combinations of imidazole derivatives, Heterocyclic Compounds, 1-Ring
  3. Drug

    Ambrisentan

    go.drugbank.com/drugs/DB06403
    ApprovedInvestigational

    Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. … In addition, it is approved in the United States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and to improve exercise ability.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid
  4. Indication

    Polyneuropathies

    go.drugbank.com/conditions/DBCOND0030109
    Drugs: Vutrisiran
    Synonyms: Other neurologic disorders in Lyme disease
  5. Indication

    Elevation of serum triglyceride levels

    go.drugbank.com/conditions/DBCOND0097366
    Drugs: Atorvastatin · Lovastatin · Pitavastatin · Pravastatin
    Synonyms: Increases in triglycerides, Increase in blood triglycerides
  6. Drug

    Conjugated estrogens

    go.drugbank.com/drugs/DB00286
    ApprovedInvestigational

    [T475] The conjugated estrogen mixture was approved for marketing in US in 1942 based on the efficacy against certain conditions. … Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.

    Categories: Sex Hormones and Modulators of the Genital System, Cytochrome P-450 SubstratesProducts: Premarin Inj 25mg/5ml, TROMODIL-V
  7. Drug

    Methyldopa

    go.drugbank.com/drugs/DB00968
    ApprovedInvestigational

    [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. … [A232224] First introduced in 1960 as an antihypertensive agent, methyldopa was considered to be useful in certain patient populations, such as pregnant women and patients with renal insufficiency.

    Synonyms: α-methyl-L-dopa, 3-Hydroxy-alpha-methyl-L-tyrosineCategories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic Agonist
  8. Target

    Interferon-inducible protein AIM2

    go.drugbank.com/bio_entities/BE0011287
    TargetHumans

    Inflammasomes are supramolecular complexes that assemble in the cytosol in response to pathogens and other damage-associated signals and play critical roles in innate immunity and inflammation (PubMed: … Also acts as a regulator of neurodevelopment via its role in the DNA damage response: acts by promoting neural cell death in response to DNA damage in the developing brain, thereby purging genetically

    Synonyms: Absent in melanoma 2
  9. Indication

    Vomit

    go.drugbank.com/conditions/DBCOND0052584
    Drugs: Benzocaine · Bromopride · Dimenhydrinate · Doxylamine · Itopride · Pipenzolate +3 more
    Synonyms: (Vomiting (& [C/O] or [symptoms])) or (rumination)
  10. Drug

    Zinc sulfate

    go.drugbank.com/drugs/DB09322
    ApprovedInvestigational

    It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".

    Mixtures: Rohto All-In-One, M T E 4 Concentrate InjCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use