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Cholic Acid
go.drugbank.com/drugs/DB02659ApprovedInvestigational[PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single
Sodium acetate
go.drugbank.com/drugs/DB09395ApprovedInvestigationalIt is mainly indicated to correct sodium levels in hyponatremic patients. It can be used also in metabolic acidosis and for urine alkalinization.
Mixtures: OLICLINOMEL N4-550 E EMULSION FOR INFUSION, OLICLINOMEL N7-1000 E EMULSION FOR INFUSIONBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigationalBaloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation. … [A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure.
Leucine
go.drugbank.com/drugs/DB00149ApprovedInvestigationalNutraceuticalAn essential branched-chain amino acid important for hemoglobin formation.
Mixtures: Vamin N, AMINOSTERIL N-HEPA 8%Anthrax vaccine
go.drugbank.com/drugs/DB11003ApprovedInvestigationalIt is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis which are grown in a chemically defined protein-free medium. … [L47526] It is considered one of the most likely agents to be used in a biological attack.
Viper antivenom
go.drugbank.com/drugs/DB14114ApprovedInvestigationalANAVIP, an equine-derived antivenom made with venom from _Bothrops asper_ and _Crotalus durissus_, was first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation … Viper antivenom consists of antibodies derived from horses immunized and subsequently developed antibodies against snake venoms.
Lanadelumab
go.drugbank.com/drugs/DB14597ApprovedInvestigational[A38676] Lanadelumab was approved for use in patients with hereditary angioedema by the FDA in August 2018,[L4537] followed by Health Canada in October 2018[L49226] and the EMA in November 2018.
Aminoglutethimide
go.drugbank.com/drugs/DB00357ApprovedWithdrawnAn aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p454)
Helminth Infection
go.drugbank.com/conditions/DBCOND0082009Synonyms: Infection due to Class Cestoda and/or Class Trematoda and/or Phylum NemataZiconotide
go.drugbank.com/drugs/DB06283ApprovedInvestigational[A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling. … [L13389] To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA.[A202835]
Categories: Calcium Channels, N-Type, N-Calcium Channel Receptor Antagonists