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Bevantolol
go.drugbank.com/drugs/DB01295InvestigationalBevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonis...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSt. John's Wort
go.drugbank.com/drugs/DB01323ApprovedNutraceuticalCategories: P-glycoprotein inducers, Cytochrome P-450 SubstratesCilazapril
go.drugbank.com/drugs/DB01340ApprovedInvestigationalCilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorp...
Categories: P-glycoprotein inhibitorsClenbuterol
go.drugbank.com/drugs/DB01407ApprovedInvestigationalVet approvedA substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Mixtures: EBROMIN-PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesTiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigationalTiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth musc...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAprindine
go.drugbank.com/drugs/DB01429ExperimentalAprindine is a cardiac depressant used in arrhythmias.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesEthylmorphine
go.drugbank.com/drugs/DB01466IllicitInvestigationalA narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. I...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesCarfentanil
go.drugbank.com/drugs/DB01535IllicitInvestigationalVet approvedCarfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known (also the most potent opioid used commercially). Carfentanil was first synthesized in 197...
Dextroamphetamine
go.drugbank.com/drugs/DB01576ApprovedIllicitInvestigationalDextroamphetamine is the dextrorotatory enantiomer of amphetamine . Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSolifenacin
go.drugbank.com/drugs/DB01591ApprovedInvestigationalSolifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily. Solifenacin was g...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates