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Displaying results 1781 - 1790 of 10000 in total
  1. Pathway

    Fluorometholone Action Pathway

    smpdb.ca/view/SMP0126255
    Drug action

    Fluorometholone is a glucocorticoid used for the relief of inflammation located in the eyes. This drug is also used in the treatment of many skin disorders. As fluorometholone is a glucocorticoid, its mechanism of action is that of the g...

    Drugs: Glutathione · Fluorometholone · Dinoprostone · Calcium · Prostaglandin D2 · Mesoheme +2 more
    Enzymes: Prostaglandin E synthase
  2. Pathway

    Medrysone Action Pathway

    smpdb.ca/view/SMP0126256
    Drug action

    Medrysone is a glucocorticoid used in the treatment of various ocular inflammatory or allergic conditions. As medrysone is a glucocorticoid, its mechanism of action is that of the glucocorticoid response element of influencing COX-2/pros...

    Drugs: Glutathione · Medrysone · Dinoprostone · Calcium · Prostaglandin D2 · Mesoheme +2 more
    Enzymes: Prostaglandin E synthase
  3. Drug

    Pegloticase

    go.drugbank.com/drugs/DB09208
    ApprovedInvestigational

    [L42425] Pegloticase has a longer terminal elimination half-life thanks to the addition of a polyethylene glycol (PEG) group. … Therefore therapeutic drug levels can be maintained with infrequent and relatively low pegloticase doses.[A249980] The PEG group also gives pegloticase a lower potential to induce an immune response.

    Categories: Compounds used in a research, industrial, or household setting
  4. Target

    Discoidin domain receptor

    go.drugbank.com/bio_entities/BE0027487
    TargetHumans

    Tyrosine kinase involved in the regulation of tissues remodeling (PubMed:30449416). It functions as a cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration...

    Synonyms: TRK E
  5. Drug

    Sofosbuvir

    go.drugbank.com/drugs/DB08934
    ApprovedInvestigational

    With the price per pill set at $1000, a 12-week treatment can cost upwards of $84,000 per patient [A19636]. … As a prodrug nucleotide analog, Sofosbuvir is metabolized into its active form as the antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective

    Mixtures: HARVONI®, EPCLUSA®Categories: P-glycoprotein substrates, Treatments for Hepatitis C
  6. Drug

    Bimatoprost

    go.drugbank.com/drugs/DB00905
    ApprovedInvestigational

    Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. … [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug

    Mixtures: Bimatoprost/Timolol 1A Pharma 0,3 mg/ml + 5 mg/ml - Augentropfen, Lösung, BIMATOPROST E TIMOLOLO EGCategories: Cytochrome P-450 Substrates, Prostaglandins F, Synthetic
  7. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:1(9Z)/18:4(6Z,9Z,12Z,15Z))

    smpdb.ca/view/SMP0015096
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  8. Pathway

    Phosphatidylethanolamine Biosynthesis PE(15:0/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0015138
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  9. Pathway

    Phosphatidylethanolamine Biosynthesis PE(16:0/20:5(5Z,8Z,11Z,14Z,17Z))

    smpdb.ca/view/SMP0015162
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  10. Pathway

    Phosphatidylethanolamine Biosynthesis PE(16:0/22:5(7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0015168
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more