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Pentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalIt is also synergistic with some other antineoplastic agents and has immunosuppressive activity. … The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: Nipent Pws 10mg/vialSalix alba bark
go.drugbank.com/drugs/DB14274ApprovedSalix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Herbal Cold and Flu Formula - TabCategories: Herbs and Natural ProductsTolmetin
go.drugbank.com/drugs/DB00500ApprovedA non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Categories: Acetic Acid Derivatives and Related Substances, Antiinflammatory and Antirheumatic ProductsProducts: Tolectin 400 Cap 400mg, Tolectin Tab 600mgNKG2D-ACE2 CAR-NK Cell
go.drugbank.com/drugs/DB15727InvestigationalThese cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. … The IL-15 superagonist increases the activity of NK cells and improves their target cytotoxicity. The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity.
Synonyms: ACE2 CAR-NK Cell, NKG2D CAR-NK CellHydroxide ion
go.drugbank.com/drugs/DB14522InvestigationalMixtures: OHTrust Nano Ion WaterSynonyms: Hydroxide ionPuberty, Delayed
go.drugbank.com/conditions/DBCOND0001010Synonyms: Delay in sexual development AND/OR puberty (finding), Delay in sexual development and puberty, NEC -RETIRED-Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
go.drugbank.com/bio_entities/BE0002195TargetEnzymeHumansCatalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:25419660). … Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (PubMed:11956192, PubMed:12475640, PubMed:18298658, PubMed:18834968, PubMed:30089812
Polypeptides: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3Disintegrin and metalloproteinase domain-containing protein 9
go.drugbank.com/bio_entities/BE0003412TargetHumansMetalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. … May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 9Sodium- and chloride-dependent GABA transporter 3
go.drugbank.com/bio_entities/BE0004733TargetHumansCan also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity) … Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).
Polypeptides: Sodium- and chloride-dependent GABA transporter 3Disintegrin and metalloproteinase domain-containing protein 33
go.drugbank.com/bio_entities/BE0019245TargetHumansPromotes and maintains a proliferative phenotype in vascular smooth muscle cells through regulation of the PI3K/AKT and ERK signaling pathways (PubMed:33982767). … Metalloprotease that cleaves and sheds the ectodomains of cell-surface proteins and thereby contributes to angiogenesis, cell differentiation, inflammation, and cell proliferation (PubMed:14676211, PubMed
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 33