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Chronic Granulocytic Leukemias
go.drugbank.com/conditions/DBCOND0143005Drugs: CyclophosphamideSynonyms: Chronic myelogenous leukemia, no ICD-O subtype, Chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality)Sodium chlorite
go.drugbank.com/drugs/DB13210InvestigationalFood and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413]. … Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S.
Categories: Preparations for Treatment of Wounds and UlcersProducts: PURE O2 Pack-Solid, Qve - SGTP-binding protein Rheb
go.drugbank.com/bio_entities/BE0004594TargetHumansIn response to starvation, RHEB is inactivated by the TSC-TBC complex, preventing activation of mTORC1 (PubMed:24529379, PubMed:33157014). Has low intrinsic GTPase activity (PubMed:15340059) … In response to nutrients, growth factors or amino acids, specifically activates the protein kinase activity of MTOR, the catalytic component of the mTORC1 complex: acts by causing a conformational change
Synonyms: Ras homolog enriched in brainDegenerative Joint Disease of Hip
go.drugbank.com/conditions/DBCOND0110588Drugs: DiacereinSynonyms: O/A, Osteoarthritis in the Hip JointStannous fluoride
go.drugbank.com/drugs/DB11092ApprovedInvestigationalStannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. … Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental
Synonyms: Tin(II) fluoride, tin difluorideCategories: Compounds used in a research, industrial, or household setting, Tin CompoundsSunitinib
go.drugbank.com/drugs/DB01268ApprovedInvestigationalSunitinib also inhibits KIT (CD117), the RTK that drives the majority of GISTs. In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3. … Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: SUNITINIB DR. REDDY'S, DOSTINIB® 25MGHuntington's Disease (HD)
go.drugbank.com/conditions/DBCOND0053941Synonyms: [X]Dementia in Huntington's disease (disorder)Ioversol
go.drugbank.com/drugs/DB09134ApprovedInvestigationalIoversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. … [L41790] The intravascular administration of iodine compounds, such as ioversol, enhances the contrast between vessels in the path of the flow of the contrast medium and normal tissue, allowing the visualization
Synonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamideCategories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsPhosphoserine phosphatase
go.drugbank.com/bio_entities/BE0004590TargetHumansMay also act on O-phospho-D-serine (Probable) … Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine (PubMed:12213811, PubMed:14673469, PubMed:15291819, PubMed
Synonyms: O-phosphoserine phosphohydrolase