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Beta Oxidation of Very Long Chain Fatty Acids
smpdb.ca/view/SMP0000052MetabolicWith each turn of the cycle two carbons are removed from the fatty acid chain and the energy of the chemical bonds once housed by the molecule is captured by the reduced energy carriers NADH and FADH2. … The oxidation of fatty acid chains is a process of progress through repetition.
Enzymes: Long-chain-fatty-acid--CoA ligase 1Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
smpdb.ca/view/SMP0000482Metaboliccycle) and uses trifunctional enzyme subunits alpha and beta to create palmityl-CoA. … Fatty acids and their CoA byproducts can be found in many places in the body, playing major roles in many basic functions of the body.
Drugs: Adenosine phosphate · NADH · ATP · Levocarnitine · Magnesium cation · Flavin adenine dinucleotide +2 moreEnzymes: Long-chain-fatty-acid--CoA ligase 1Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
smpdb.ca/view/SMP0000480MetabolicFatty acids and their CoA esters are found throughout the body, playing roles such as components of cellular lipids, regulators of enzymes and membrane channels, ligands for nuclear receptors, precursor … Acetyl-CoA can then enter the citric acid cycle.
Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids
smpdb.ca/view/SMP0000481MetabolicFatty acids and their CoA esters are found throughout the body, playing roles such as components of cellular lipids, regulators of enzymes and membrane channels, ligands for nuclear receptors, precursor … Beta-oxidation is the major degradative pathway for fatty acid esters in humans.
Drugs: Adenosine phosphate · NADH · ATP · Magnesium cation · Lauric acid · Flavin adenine dinucleotide +1 moreLorazepam Action Pathway
smpdb.ca/view/SMP0125053Drug action, chemotherapy-associated anticipatory nausea and vomiting, and psychogenic catatonia. … It is as well used as an anesthesia premedication in adults to relieve anxiety or to produce sedation/amnesia and for the treatment of status epilepticus.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Clonazepam Action Pathway
smpdb.ca/view/SMP0125054Drug actionanticonvulsant activity, and anxiolytic action. … In particular, when out of the ordinary rapid and repetitive electrical signals are released in the CNS, it is proposed that the brain can become over-stimulated and ordinary functions are disrupted -
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Midazolam Action Pathway
smpdb.ca/view/SMP0125055Drug actionMidazolam is administered in a variety of ways including intravenous and intramuscular injection and as a buccal solution, … anticonvulsant activity, and anxiolytic action.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Bromazepam Action Pathway
smpdb.ca/view/SMP0125070Drug actionBromazepam is a lipophilic, long-acting benzodiazepine and with sedative, hypnotic, anxiolytic and skeletal muscle relaxant properties. It does not possess any antidepressant qualities. … Bromazepam, like other benzodiazepines, presents a risk of abuse, misuse, and dependence.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Zolpidem Action Pathway (New)
smpdb.ca/view/SMP0125072Drug actionThis binding will result in an increase on the GABA inhibitory effects which is translated as an increase in the flow of chloride ions into the cell causing hyperpolarization and stabilization of the cellular … Zolpidem binding to the GABAA receptor chloride channel macromolecular complex is thought to lead to the sedative, anticonvulsant, anxiolytic, and myorelaxant drug effects of the drug.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Triazolam Action Pathway
smpdb.ca/view/SMP0126116Drug actionThese receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. … Benzodiazepines bind nonspecifically to BNZ1, which acts on sleep, and BNZ2, which acts on muscle relaxation, anticonvulsant activity, motor coordination, and memory.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1