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Displaying results 171 - 180 of 10000 in total
  1. Pathway

    Indium In-111 pentetate Drug Metabolism

    smpdb.ca/view/SMP0130595
    Metabolic

    Indium In-111 pentetate passes through the liver and is then excreted from the body mainly through the kidney. … Indium In-111 pentetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Indium In-111 pentetate
  2. Drug

    Rabies immune globulin, human

    go.drugbank.com/drugs/DB11603
    Approved

    IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced … Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and a cell culture-produced

    Products: Hyperrab S/d, Rabipur Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze
  3. Drug

    Technetium Tc-99m mebrofenin

    go.drugbank.com/drugs/DB09137
    ApprovedWithdrawn

    Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. … Liver and gallbladder imaging is enabled through attachment to mebrofenin as this molecule has high hepatic uptake and fast biliary excretion, resulting in improved hepatic imaging.

    Categories: Compounds used in a research, industrial, or household settingProducts: KIT PARA LA PREPARACIÓN DE MEBROFENINA- TC99M
  4. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    [L40719] It has a number of therapeutic uses, including the management and prevention of infections and febrile neutropenia in patients receiving myelosuppressive chemotherapy or radiation therapy. … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_.

    Products: ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML, ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML
  5. Drug

    Golimumab

    go.drugbank.com/drugs/DB06674
    ApprovedInvestigational

    Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate … treatment in patients with active psoriatic arthritis (PsA), (iii) as a single agent in patients with active ankylosing spondylitis (AS), and (iv) as a single agent in patients with moderate to severe

    Products: SIMPONI 50MG ILO I E FER, SIMPONI 100MG ILO IN FER
  6. Pathway

    Fc Epsilon Receptor I Signaling in Mast Cells

    smpdb.ca/view/SMP0000358
    Signaling

    The release of these compounds results in the inflammatory response. … Fc epsilon receptor 1 (Fc epsilon RI) is a high-affinity receptor for the Fc region of immunoglobulin E (IgE), an antibody isotope involved in allergies.

    Drugs: Heparin · Calcium · Magnesium cation · Zinc · Prostaglandin D2 · Arachidonic Acid
  7. Drug

    Panthenol

    go.drugbank.com/drugs/DB11204
    Approved

    Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.

    Mixtures: Foasu Jin Powderwash, bdr Re-lax 3 multiple level serum highly-potential youthSynonyms: DL-panthenol, DL-Pantothenol
  8. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. … Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label].

    Synonyms: (S)-Pregn-4-en-3,20-dioneInternational brands: Qi Ning
  9. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    and use, including the development of orally soluble films that are both discreet in administration and less of a burden in comparison to having patients attempt to swallow pills during emesis. … [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation.

    Products: NODANTON-I, Zofran 4mg in 2ml Solution for Injection
  10. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. … It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring.

    Mixtures: DIPIRONA N- BULTILBROMURO DE HIOSCINA, ACETAMINOFÉN 325 MG + N-BUTILBROMURO DE HIOSCINA 10 MGSynonyms: N-butylscopolammonium ion, N-butylscopolammonium