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Displaying results 171 - 180 of 1073 in total
  1. Indication

    Early Stage Estrogen Receptor (ER) Positive Breast Cancer

    go.drugbank.com/conditions/DBCOND0068305
    Drugs: Tamoxifen
    Synonyms: Early Stage Estrogen Receptor (ER) Positive Breast Cancer
  2. Drug

    Famtozinameran

    go.drugbank.com/drugs/DB17088
    ApprovedInvestigational

    The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). ...

  3. Drug

    Anbenitamab

    go.drugbank.com/drugs/DB18411
    Investigational

    Synonyms: IMMUNOGLOBULIN G1 (369-SERINE,371-ALANINE,408-LYSINE,410-VALINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER2 DOMAIN IV)(HUMAN-MUS MUSCULUS MONOCLONAL RHUMAB 4D5 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS
  4. Target

    Insulin receptor

    go.drugbank.com/bio_entities/BE0000033
    TargetHumans

    When present in a hybrid receptor with IGF1R, binds IGF1. … Receptor tyrosine kinase which mediates the pleiotropic actions of insulin.

    Polypeptides: Insulin receptor
  5. Target

    Estrogen receptor

    go.drugbank.com/bio_entities/BE0000123
    TargetHumans

    Nuclear hormone receptor. … Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner.

    Polypeptides: Estrogen receptorSynonyms: Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
  6. Target

    Secretin receptor

    go.drugbank.com/bio_entities/BE0000318
    TargetHumans

    G protein-coupled receptor activated by secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:25332973 … Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain

    Polypeptides: Secretin receptorFunction: G protein-coupled peptide receptor activity
  7. Target

    Prolactin receptor

    go.drugbank.com/bio_entities/BE0000345
    TargetHumans

    This is a receptor for the anterior pituitary hormone prolactin (PRL).

    Polypeptides: Prolactin receptor
  8. Target

    Thyrotropin receptor

    go.drugbank.com/bio_entities/BE0000490
    TargetHumans

    Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). … Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258).

    Polypeptides: Thyrotropin receptorSynonyms: Thyroid-stimulating hormone receptor
  9. Target

    Progesterone receptor

    go.drugbank.com/bio_entities/BE0000557
    TargetHumans

    Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor

    Polypeptides: Progesterone receptorSynonyms: Nuclear receptor subfamily 3 group C member 3
  10. Target

    Glucocorticoid receptor

    go.drugbank.com/bio_entities/BE0000794
    TargetHumans

    Receptor for glucocorticoids (GC) (PubMed:27120390, PubMed:37478846).

    Polypeptides: Glucocorticoid receptorSynonyms: Nuclear receptor subfamily 3 group C member 1