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Clioquinol
go.drugbank.com/drugs/DB04815ApprovedVet approvedWithdrawnClioquinol was withdrawn in 1983 due to neurotoxicity.
Categories: Genito Urinary System and Sex HormonesSulfathiazole
go.drugbank.com/drugs/DB06147ApprovedVet approvedWithdrawnSulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamid...
Categories: Genito Urinary System and Sex HormonesSulfametopyrazine
go.drugbank.com/drugs/DB00664ApprovedWithdrawnLong-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.
Categories: Genito Urinary System and Sex HormonesGlucagon
go.drugbank.com/drugs/DB00040ApprovedInvestigationalGlucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia. Glucagon raises blood sugar through activation of hepati...
Categories: Sex Hormones and InsulinsFesoterodine
go.drugbank.com/drugs/DB06702ApprovedFesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Categories: Genito Urinary System and Sex HormonesCyclin-dependent kinase 9
go.drugbank.com/bio_entities/BE0002207TargetHumansThis complex is inactive when in the 7SK snRNP complex form (PubMed:10574912, PubMed:10757782, PubMed:11145967, PubMed:11575923, PubMed:11809800, PubMed:11884399, PubMed:14701750, PubMed:16109376, PubMed … The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro (PubMed:21127351).
Synonyms: Tat-associated kinase complex catalytic subunitProteasome subunit beta type-5
go.drugbank.com/bio_entities/BE0002348TargetHumansWithin the 20S core complex, PSMB5 displays a chymotrypsin-like activity … Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.
Synonyms: Multicatalytic endopeptidase complex epsilon chainMethallenestril
go.drugbank.com/drugs/DB13143ExperimentalCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemMethylestrenolone
go.drugbank.com/drugs/DB13533InvestigationalCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemProteasome subunit beta type-4
go.drugbank.com/bio_entities/BE0003918TargetHumansNon-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Synonyms: Multicatalytic endopeptidase complex beta chain