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Displaying results 1811 - 1820 of 10000 in total
  1. Drug

    Vildagliptin

    go.drugbank.com/drugs/DB04876
    ApprovedInvestigational

    [A232488] Oral vildagliptin was approved by the European Medicines Agency in 2008 for the treatment of type II diabetes mellitus in adults as monotherapy or in combination with [metformin], a sulfonylurea … It is marketed as Galvus.[L32803] Vildagliptin is also available as Eucreas, a fixed-dose formulation with metformin for adults in who do not adequately glycemic control from monotherapy.

    Mixtures: GLIMETAL-DP, JALRA ®M 50 MG /500 MGCategories: Drugs Used in Diabetes, DPP-IV Inhibitors
  2. Indication

    Leukemias

    go.drugbank.com/conditions/DBCOND0035632
    Drugs: Betamethasone · Bupivacaine · Hydrocortisone · Hydrocortisone succinate · Methylprednisolone · Methylprednisolone hemisuccinate +2 more
    Synonyms: Leukemia, no ICD-O subtype, Leukaemia, no ICD-O subtype
  3. Drug

    Avobenzone

    go.drugbank.com/drugs/DB09495
    ApprovedInvestigational

    Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers are added in the sunscreen product. Avobenzone has an absorption maximum of 357 nm. … In addition to limiting the skin's exposure to the sun, using sunscreen agents may help reduce long-term sun damage such as premature aging of the skin and skin cancer.

    Mixtures: Ultra Correction Line Repair - CRème De Jour Anti-rides, Ultra Correction Line Repair - Fluide De Jour Anti-ridesCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 Substrates
  4. Drug

    Cefpodoxime

    go.drugbank.com/drugs/DB01416
    ApprovedInvestigationalVet approved

    Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. … Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria.

    Mixtures: INFEX PLUS 100/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML, INFEX PLUS 40/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 MLCategories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site.

    Categories: combinations of tetracyclines, Cytochrome P-450 SubstratesSynonyms: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
  6. Drug

    Amantadine

    go.drugbank.com/drugs/DB00915
    ApprovedInvestigational

    An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.

    Mixtures: ROSEL-T, Innoprax-5Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Influenza A M2 Protein Inhibitor
  7. Target

    Lysophosphatidylcholine acyltransferase 2

    go.drugbank.com/bio_entities/BE0016122
    TargetEnzymeHumans

    Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine … Involved in the regulation of lipid droplet number and size (PubMed:25491198)

    Synonyms: 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-acylglycerophosphocholine O-acyltransferaseFunction: 1-acylglycerol-3-phosphate O-acyltransferase activity
  8. Indication

    Chronic Myelogenous Leukemia (CML)

    go.drugbank.com/conditions/DBCOND0040386
    Drugs: Busulfan · Hydroxyurea · Interferon alfa-2a
    Synonyms: Chronic myelogenous leukemia, no ICD-O subtype, Chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality)
  9. Indication

    Gestational Diabetes Mellitus (GDM)

    go.drugbank.com/conditions/DBCOND0043991
    Drugs: Glyburide · Insulin aspart · Insulin lispro
    Synonyms: Diabetes mellitus arising in pregnancy
  10. Drug

    Bismuth subsalicylate

    go.drugbank.com/drugs/DB01294
    ApprovedVet approved

    [A230728] It is an active ingredient found in Pepto-Bismol, a common over-the-counter medication that is used to temporarily treat discomforts of the stomach and gastrointestinal tract. … [A230728, A230773] Bismuth subsalicylate was first approved by the FDA in 1939 and is now mainly used to relieve nausea, diarrhea, and gastrointestinal discomfort.

    Mixtures: Pepto-Bismol and Pepto-Bismol To Go, Pepto-Bismol and Pepto-Bismol To GoSynonyms: 2-Hydroxy-benzo[1,3,2]dioxabismin-4-one