Search
Delta-type opioid receptor
go.drugbank.com/bio_entities/BE0000420TargetHumansG protein-coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids.
Polypeptides: Delta-type opioid receptorFunction: G protein-coupled enkephalin receptor activity5-hydroxytryptamine receptor 2A
go.drugbank.com/bio_entities/BE0000451TargetHumansPlays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction (By similarity) … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895, PubMed:21645528, PubMed:22300836, PubMed:35084960, PubMed:38552625).
Polypeptides: 5-hydroxytryptamine receptor 2ASynonyms: Serotonin receptor 2ANeurotensin receptor type 2
go.drugbank.com/bio_entities/BE0000464TargetHumansReceptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Neurotensin receptor type 2Synonyms: Levocabastine-sensitive neurotensin receptorMelatonin receptor type 1A
go.drugbank.com/bio_entities/BE0000515TargetHumansHigh affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. … The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Polypeptides: Melatonin receptor type 1ASynonyms: Mel1a receptorMuscarinic acetylcholine receptor M2
go.drugbank.com/bio_entities/BE0000560TargetHumansMuscarinic receptor for acetylcholine, a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia (PubMed:24256733, PubMed:3443095, PubMed:36690613).
Polypeptides: Muscarinic acetylcholine receptor M2Alpha-2B adrenergic receptor
go.drugbank.com/bio_entities/BE0000572TargetHumansAlpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression (PubM...
Polypeptides: Alpha-2B adrenergic receptorSynonyms: Alpha-2 adrenergic receptor subtype C2Hydroxycarboxylic acid receptor 2
go.drugbank.com/bio_entities/BE0000635TargetHumansReceptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis … Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated
Polypeptides: Hydroxycarboxylic acid receptor 2Synonyms: Niacin receptor 1, Nicotinic acid receptor5-hydroxytryptamine receptor 1D
go.drugbank.com/bio_entities/BE0000659TargetHumansMay also play a role in regulating the release of other neurotransmitters (PubMed:18476671, PubMed:20945968). May play a role in vasoconstriction (PubMed:18476671, PubMed:20945968) … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:10452531, PubMed:1565658, PubMed:1652050, PubMed:33762731).
Polypeptides: 5-hydroxytryptamine receptor 1DSynonyms: Serotonin receptor 1D, Serotonin 1D alpha receptorRetinoic acid receptor alpha
go.drugbank.com/bio_entities/BE0000663TargetHumansReceptor for retinoic acid (PubMed:16417524, PubMed:19850744, PubMed:20215566, PubMed:21152046, PubMed:37478846). … In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes (By similarity).
Polypeptides: Retinoic acid receptor alphaSynonyms: Nuclear receptor subfamily 1 group B member 1Thyroid hormone receptor alpha
go.drugbank.com/bio_entities/BE0000687TargetHumansNuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine
Polypeptides: Thyroid hormone receptor alphaSynonyms: Nuclear receptor subfamily 1 group A member 1