Retinoic acid receptor alpha

BE0000663ProteinHumansRARA

Receptor for retinoic acid (PubMed:16417524, PubMed:19850744, PubMed:20215566, PubMed:21152046, PubMed:37478846). It is acted on by 16 drugs in DrugBank.

Gene name
RARA
UniProtKB entry
P10276Swiss-Prot
Cellular location
Nucleus
Residues / weight
462 residues · 50,771 Da
Also known as
NR1B1 · Nuclear receptor subfamily 1 group B member 1 · RAR-alpha

Resolves to

Protein
UniProtP10276UniProt nameRARA_HUMAN
Gene
HGNCHGNC:9864NCBI Gene5914GenBank36157GeneCardsRARA
Pharmacology
IUPHAR/GtoPdb590KEGGhsa:5914
Structure
PDB1DKFPDB1DSZPDB3A9E
Drugs

What you can answer from here — as of September 07, 2019

16DrugsApproved to experimental, with action, bond type and pharmacological action
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11Clinical trialsTrials of drugs acting on it, by phase and status
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44GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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108+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Retinoic acid receptor alpha, how selective are they, and which programs against it are still in active trials?

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