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Displaying results 181 - 190 of 134146 in total
  1. Pathway

    Nizatidine H2 Anti-Histamine Action Pathway

    smpdb.ca/view/SMP0126776
    Drug action

    This transports hydrogen into the stomach lumen where it reacts with chloride to synthesize hydrochloric acid, a large component of gastric acid. … Nizatidine is an H2 Histamine receptor antagonist used to treat acid reflux disorders and a variety of ulcers. Nizatidine is taken orally as a solution or a capsule.

    Drugs: ATP · Nizatidine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate
    Enzymes: Chloride anion exchanger
  2. Pathway

    Lavoltidine H2 Anti-histamine Action Pathway

    smpdb.ca/view/SMP0126790
    Drug action

    Lavoltidine has been used in trials studying the diagnostic of Reflux, Gastroesophageal and Gastroesophageal Reflux Disease. … After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stomach epithelium.

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Lavoltidine
    Enzymes: Chloride anion exchanger
  3. Pathway

    Polythiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123144
    Drug action

    Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood. … In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs.

    Drugs: Polythiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka
  4. Pathway

    Cyclothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123145
    Drug action

    Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood. … In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur.

    Drugs: Cyclothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka
  5. Pathway

    Benzthiazide Action Pathway

    smpdb.ca/view/SMP0126366
    Drug action

    This inhibition of the cotransporter results in the increased excretion of sodium, chloride, and, in consequence, water. … This drug is used in the treatment of hypertension and edema. They act on the kidneys by inhibiting the sodium-chloride reabsorption (via the Na+/Cl- cotransporter) from its early distal tubules.

    Drugs: Benzthiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka
  6. Pathway

    Bendroflumethiazide Action Pathway (New)

    smpdb.ca/view/SMP0123062
    Drug action

    Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood. … In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs.

    Drugs: Bendroflumethiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka
  7. Pathway

    Chlorothiazide Action Pathway

    smpdb.ca/view/SMP0123141
    Drug action

    Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood. … In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occurs.

    Drugs: Chlorothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka
  8. Pathway

    Methyclothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123143
    Drug action

    Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood. … In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur.

    Drugs: Methyclothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka
  9. Pathway

    Trichlormethiazide Action Pathway (New)

    smpdb.ca/view/SMP0123150
    Drug action

    Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood. … In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs.

    Drugs: Trichlormethiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka
  10. Pathway

    Metolazone Action Pathway

    smpdb.ca/view/SMP0123151
    Drug action

    Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood. … In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur.

    Drugs: Metolazone · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka