Search

Displaying results 181 - 190 of 301 in total
  1. Drug

    Brexanolone

    go.drugbank.com/drugs/DB11859
    ApprovedInvestigational

    brexanolone may also be undergoing clinical trials to investigate its abilities to treat super-refractory status epilepticus, it appears that some such studies have failed to meet primary endpoints that compare

  2. Indication

    Herpes Simplex

    go.drugbank.com/conditions/DBCOND0027882
    Drugs: Lysozyme
    Synonyms: Herpes simplex complex
  3. Indication

    Herpes simplex of the oral-labial

    go.drugbank.com/conditions/DBCOND0024319
    Drugs: Acyclovir
    Synonyms: Herpes simplex complex
  4. Drug

    Sodium fluoride

    go.drugbank.com/drugs/DB09325
    ApprovedInvestigational

    Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health...

    Mixtures: Alora Whitening, Alora SensitivityProducts: Alora Whitening, Dentalux Complex 5
  5. Indication

    Endometrial Hyperplasia

    go.drugbank.com/conditions/DBCOND0001317
    Drugs: Levonorgestrel · Lynestrenol · Medroxyprogesterone acetate
    Synonyms: Complex endometrial hyperplasia (disorder)
  6. Target

    Mitochondrial ATP synthase F1 domain

    go.drugbank.com/bio_entities/BE0010209
    TargetEnzymeHumans

    ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Part of the complex F(0) domain (PubMed:37244256).

    Polypeptides: ATP synthase F(1) complex subunit alpha, mitochondrial, ATP synthase F(1) complex subunit beta, mitochondrial
  7. Target

    Lys-63-specific deubiquitinase BRCC36

    go.drugbank.com/bio_entities/BE0009071
    TargetHumans

    Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex (PubMed:19214193). … Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites

    Synonyms: BRCA1-A complex subunit BRCC36, BRISC complex subunit BRCC36
  8. Target

    Cytochrome b

    go.drugbank.com/bio_entities/BE0004428
    TargetPlasmodium falciparum

    Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

    Synonyms: Complex III subunit 3, Complex III subunit III
  9. Target

    Cytochrome c1, heme protein, mitochondrial

    go.drugbank.com/bio_entities/BE0003854
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Synonyms: Complex III subunit 4, Complex III subunit IV
  10. Target

    Cytochrome b

    go.drugbank.com/bio_entities/BE0000938
    TargetHumans

    Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis

    Synonyms: Complex III subunit 3, Complex III subunit III