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Prohibitin-2
go.drugbank.com/bio_entities/BE0009007TargetHumansProtein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcrip...
Synonyms: B-cell receptor-associated protein BAP37, Repressor of estrogen receptor activityATP-binding cassette sub-family C member 8
go.drugbank.com/bio_entities/BE0000207TargetTransporterHumansRegulator subunit of pancreatic ATP-sensitive potassium channel (KATP), playing a major role in the regulation of insulin release. In pancreatic cells, it forms KATP channels with KCNJ11; KCNJ11 forms the channel pore while ABCC8 is requ...
Synonyms: Sulfonylurea receptor 1Intercellular adhesion molecule 1
go.drugbank.com/bio_entities/BE0001085TargetHumansAlso functions as a ligand receptor of the signaling receptor ITGAM:ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed:1980124). … Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing
Synonyms: Major group rhinovirus receptorCD27 antigen
go.drugbank.com/bio_entities/BE0010071TargetHumansCostimulatory immune-checkpoint receptor expressed at the surface of T-cells, NK-cells and B-cells which binds to and is activated by its ligand CD70/CD27L expressed by B-cells (PubMed:28011863).
Synonyms: CD27L receptor, Tumor necrosis factor receptor superfamily member 7Sulfamethoxazole
go.drugbank.com/drugs/DB01015ApprovedInvestigationalSulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic ac...
Mixtures: SEPTRIN PED. 100 ML SURUP, TRIMOKS PED. 100 ML SUSPANSIYONNectin-4
go.drugbank.com/bio_entities/BE0009798TargetHumansDoes not act as receptor for alpha-herpesvirus entry into cells
Synonyms: Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4NKG2-A/NKG2-B type II integral membrane protein
go.drugbank.com/bio_entities/BE0010560TargetHumansImmune inhibitory receptor involved in self-nonself discrimination. … Key inhibitory receptor on natural killer (NK) cells that regulates their activation and effector functions (PubMed:30860984, PubMed:9430220, PubMed:9485206, PubMed:9486650).
Synonyms: NK cell receptor A, NKG2-A/B-activating NK receptorFunction: HLA-E specific inhibitory MHC class Ib receptor activityAbivertinib
go.drugbank.com/drugs/DB15327Investigational[L17388] Abivertinib's potential to depress cytokine production has led to its investigation in the treatment of hospitalized patients with moderate-to-severe COVID-19. … Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK).
Codeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalThe relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US...
Mixtures: 282 Mep Tab, Pro-red AcCollectin-12
go.drugbank.com/bio_entities/BE0015432TargetHumansScavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast.
Synonyms: Nurse cell scavenger receptor 2, Scavenger receptor class A member 4