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Ephrin-B2
go.drugbank.com/bio_entities/BE0010647TargetHumansBinds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. … The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
Synonyms: EPH-related receptor tyrosine kinase ligand 5Function: ephrin receptor bindingC-type lectin domain family 12 member A
go.drugbank.com/bio_entities/BE0010945TargetHumansAlso recognizes dead cells by acting as a receptor for monosodium urate crystals, leading to down-regulate neutrophil activation (PubMed:38367667, PubMed:38386511). … Also acts as a pattern-recognition receptor for pathogen-associated molecules, such as plasmodium hemozoin or mycobacterial micolic acid (PubMed:31269448, PubMed:36542980).
Synonyms: Killer cell C-type lectin-like receptor L1, Myeloid inhibitory C-type lectin-like receptorFunction: pattern recognition receptor activityTrimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approvedTrimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial ...
Mixtures: SEPTRIN PED. 100 ML SURUP, TRIMOKS PED. 100 ML SUSPANSIYONIntegrin beta-2
go.drugbank.com/bio_entities/BE0001041TargetHumansIntegrin ITGAM:ITGB2 is also a receptor for factor X. Integrin ITGAD:ITGB2 is a receptor for ICAM3 and VCAM1 (PubMed:10438935, PubMed:8777714, PubMed:9841932). … Integrin ITGAM:ITGB2/MAC-1 complex functions as a signaling receptor for the ligand receptor ICAM1, ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed:1980124).
Synonyms: Complement receptor C3 subunit betaSialic acid-binding Ig-like lectin 7
go.drugbank.com/bio_entities/BE0001648TargetHumansIn the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through
Synonyms: Adhesion inhibitory receptor molecule 1GTP-binding nuclear protein Ran
go.drugbank.com/bio_entities/BE0004559TargetHumansGTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed:10400640, PubMed:17209048, PubMed:26272610, PubMed:27306458, PubMed:8276887, PubMed:8636225, Pu...
Synonyms: Androgen receptor-associated protein 24Ethinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigationalEthinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitu...
Mixtures: EVELEA MD, GINELEA MDLarge ribosomal subunit protein uL16
go.drugbank.com/bio_entities/BE0009104TargetHumansComponent of the large ribosomal subunit (PubMed:26290468). Plays a role in the formation of actively translating ribosomes (PubMed:26290468). May play a role in the embryonic brain development (PubMed:25316788)
Synonyms: Laminin receptor homologIntegrin alpha-2
go.drugbank.com/bio_entities/BE0012664TargetHumansIntegrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
Synonyms: Collagen receptorAluminum hydroxide
go.drugbank.com/drugs/DB06723ApprovedInvestigationalAluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate...
Mixtures: Medi Hydro DP BB Cream