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Displaying results 1981 - 1990 of 8696 in total
  1. Target

    Acetylcholine receptor subunit alpha

    go.drugbank.com/bio_entities/BE0004661
    TargetHumans

    Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane

    Polypeptides: Acetylcholine receptor subunit alpha
  2. Target

    Hyaluronan mediated motility receptor

    go.drugbank.com/bio_entities/BE0004702
    TargetHumans

    May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity) … Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs.

    Polypeptides: Hyaluronan mediated motility receptorSynonyms: Receptor for hyaluronan-mediated motility
  3. Target

    Orexin receptor type 2

    go.drugbank.com/bio_entities/BE0005865
    TargetHumans

    G protein-coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin (PubMed:26950369, PubMed:33547286, PubMed:35614071, PubMed:9491897

    Polypeptides: Orexin receptor type 2Synonyms: Hypocretin receptor type 2
  4. Target

    Sulfonylurea receptor 1, Kir6.2

    go.drugbank.com/bio_entities/BE0008670
    TargetHumans

    Inward rectifier potassium channel that forms the pore of ATP-sensitive potassium channels (KATP), regulating potassium permeability as a function of cytoplasmic ATP and ADP concentrations in many different

    Synonyms: Sulfonylurea receptor 1
  5. Target

    Transferrin receptor protein 1

    go.drugbank.com/bio_entities/BE0008725
    TargetHumans

    Mediates uptake of NICOL1 into fibroblasts where it may regulate extracellular matrix production (By similarity) … Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738, PubMed:41772062).

    Polypeptides: Transferrin receptor protein 1Synonyms: Transferrin receptor 1
  6. Target

    Proteinase-activated receptor 4

    go.drugbank.com/bio_entities/BE0008986
    TargetHumans

    Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis (PubMed:10079109). May play a role in platelets activation (PubMed:10079109)

    Polypeptides: Proteinase-activated receptor 4Synonyms: Thrombin receptor-like 3, Coagulation factor II receptor-like 3
  7. Target

    Macrophage mannose receptor 1

    go.drugbank.com/bio_entities/BE0009334
    TargetHumans

    Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains

    Polypeptides: Macrophage mannose receptor 1Synonyms: Human mannose receptor, Macrophage mannose receptor 1-like protein 1
  8. Target

    Insulin receptor-related protein

    go.drugbank.com/bio_entities/BE0009451
    TargetHumans

    Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH.

    Polypeptides: Insulin receptor-related proteinSynonyms: IR-related receptor
  9. Target

    5-hydroxytryptamine receptor 3B

    go.drugbank.com/bio_entities/BE0009583
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3BSynonyms: Serotonin receptor 3B
  10. Target

    5-hydroxytryptamine receptor 3E

    go.drugbank.com/bio_entities/BE0009586
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3ESynonyms: Serotonin receptor 3E