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Chloride channel protein 1
go.drugbank.com/bio_entities/BE0010943TargetHumansGenerates most of the plasma membrane chloride conductance in skeletal muscle fibers, stabilizes the resting membrane potential and contributes to the repolarization phase during action potential firing … Voltage-gated chloride channel involved in skeletal muscle excitability.
Polypeptides: Chloride channel protein 1Synonyms: Chloride channel protein, skeletal muscleSodium- and chloride-dependent GABA transporter 3
go.drugbank.com/bio_entities/BE0004733TargetHumansMediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447). … Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity)
Polypeptides: Sodium- and chloride-dependent GABA transporter 3Gaba-gated chloride channel, putative
go.drugbank.com/bio_entities/BE0010256TargetPediculus humanus subsp. corporisPolypeptides: Gaba-gated chloride channel, putativeGlutamate-gated chloride channel alpha
go.drugbank.com/bio_entities/BE0027481TargetCaenorhabditis elegansGlutamate-gated chloride channel subunit; channel properties depend on the subunit composition. … The heteromeric channel formed by glc-1 and glc-2 is also activated by ibotenate, and it is blocked by picrotoxin and flufenamic acid (PubMed:7935817).
Polypeptides: Glutamate-gated chloride channel alphaSynonyms: Avermectin-sensitive glutamate-gated chloride channel GluCl alphaChloride channel protein ClC-Ka
go.drugbank.com/bio_entities/BE0002376TargetHumansAnion-selective channel permeable to small monovalent anions with ion selectivity for chloride > bromide > nitrate > iodide (PubMed:11734858, PubMed:12111250). … May conduct double-barreled currents controlled by two types of gates, two fast gates that control each subunit independently and a slow common gate that opens and shuts off both subunits simultaneously
Polypeptides: Chloride channel protein ClC-KaSynonyms: Chloride channel KaSodium-driven chloride bicarbonate exchanger
go.drugbank.com/bio_entities/BE0004683TransporterHumansHas also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange … Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride (By similarity).
Polypeptides: Sodium-driven chloride bicarbonate exchangerChloride intracellular channel protein 1
go.drugbank.com/bio_entities/BE0005284TargetHumansReduces selenite and dehydroascorbate and may act as an antioxidant during oxidative stress response (PubMed:25581026, PubMed:37759794). … Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions.
Polypeptides: Chloride intracellular channel protein 1Synonyms: Chloride channel ABP, Nuclear chloride ion channel 27Glutamate-gated chloride channel subunit beta
go.drugbank.com/bio_entities/BE0027480TargetCaenorhabditis elegansGlutamate-gated chloride channel subunit; channel properties depend on the subunit composition. … The heteromeric channel formed by glc-1 and glc-2 is also activated by ibotenate, and it is blocked by picrotoxin and flufenamic acid (PubMed:7935817).
Polypeptides: Glutamate-gated chloride channel subunit betaSynonyms: Avermectin-sensitive glutamate-gated chloride channel subunitSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
go.drugbank.com/bio_entities/BE0000423TargetTransporterHumansTransports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine (PubMed:18599538). … Can also transport carnitine, butirylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-) (PubMed:17855766)
Polypeptides: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)