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Metabolism and Physiological Effects of 3-Deoxyglucosone
smpdb.ca/view/SMP0125516MetabolicIt normally is synthesized and accumulates with high serum glucose due to diabetes. 3-deoxyglucosone causes cell apoptosis and neurotoxicity. … An amino acid like arginine or lysine are combined with glucose to make a schiff base and water. The schiff base is unstable so it becomes the stable amadori product.
Enzymes: Sodium/glucose cotransporter 1Metabolism and Physiological Effects of 4-Hydroxyhippuric Acid
smpdb.ca/view/SMP0125537Metabolic; nuts such as cashews, almonds, pistachios; and dairy products such as yogurt, milk, and cheese. … Benzoic acid is present in many fruits, such as apricots, prunes, and berries; many vegetables such as mushrooms (fungus), snap peas, cucumbers, and radishes; spices such as cinnamon, cloves, and allspice
Metabolism and Physiological Effects of N-alpha-Acetyl-L-arginine
smpdb.ca/view/SMP0125530MetabolicArginnosuccinate is synthesized from citrulline and aspartic acid by the enzyme argininosuccinate synthase. That is catalyzed by argininosuccinate lyase to produce arginine and fumaric acid. … In the blood it works as a uremic toxin to cause kidney damage, cardiovascular disease and neurological deficits.
Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 moreRabeprazole Antacid Action Pathway
smpdb.ca/view/SMP0123294Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Pantoprazole Action Pathway
smpdb.ca/view/SMP0123293Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Triamterene Action Pathway (New)
smpdb.ca/view/SMP0126281Drug actionTriamterene maintains or increases sodium excretion, thereby increasing the excretion of water, and reducing the excess loss of potassium, hydrogen, and chloride ions by inhibiting the distal tubular exchange … sodium uptake and potassium secretion.
Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1Ethacrynic Acid Diuretic Action Pathway
smpdb.ca/view/SMP0124515Drug actionThis is relieves symptoms such as swelling/ edema and hypertension in patients. Ethacrynic acid may also inhibit sodium and chloride reabsorption in the proximal and distal tubules. … Ethacrynic acid binds to NKCC2 transporter and inhibits it, preventing Na+, K+ and Cl- reabsorption from the lumen.
Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1Omeprazole Action Pathway
smpdb.ca/view/SMP0122674Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Esomeprazole Action Pathway
smpdb.ca/view/SMP0123196Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Lansoprazole Action Pathway
smpdb.ca/view/SMP0123261Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1