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Displaying results 11 - 20 of 27 in total
  1. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent to...

    Mixtures: TELDY (Dolutegravir 50mg/Lamivudine 300mg/Tenofovir Disoproxil Fumarate 300mg) Film-Coated Tablets, ACRIPTEGA DOLUTEGRAVIR/ LAMIVUDINE/TENOFOVIR DISOPROXIL FUMARATE FILM COATED TABLETS (50 MG/300 MG/300 MG)Categories: lamivudine, tenofovir disoproxil and dolutegravir, emtricitabine, tenofovir alafenamide and dolutegravir
  2. Drug

    Rilpivirine

    go.drugbank.com/drugs/DB08864
    ApprovedInvestigational

    Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpiv...

    Mixtures: Emtricitabine, Rilpivirine, Tenofovir Disoproxil Fumarate, Emtricitabine, Rilpivirine and Tenofovir Disoproxil FumarateCategories: emtricitabine, tenofovir disoproxil and rilpivirine, emtricitabine, tenofovir alafenamide and rilpivirine
  3. Drug

    Fosclevudine alafenamide

    go.drugbank.com/drugs/DB19113
    Investigational

    Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With

  4. Indication

    Chronic Hepatitis B Infection

    go.drugbank.com/conditions/DBCOND0058876
    Drugs: Adefovir dipivoxil · Entecavir · Interferon alfa-2a · Interferon alfa-2b · Lamivudine · Peginterferon alfa-2a +4 more
  5. Indication

    Human Immunodeficiency Virus Type 1 (HIV-1) Infection

    go.drugbank.com/conditions/DBCOND0045921
    Drugs: Abacavir · Atazanavir · Bictegravir · Cabotegravir · Cobicistat · Darunavir +25 more
  6. Indication

    Human Immunodeficiency Virus Type 1 (HIV-1)

    go.drugbank.com/conditions/DBCOND0042885
    Drugs: Cabotegravir · Doravirine · Enfuvirtide · Rilpivirine
  7. Indication

    HIV Transmission

    go.drugbank.com/conditions/DBCOND0044290
    Drugs: Emtricitabine · Zidovudine
  8. Indication

    Human Immunodeficiency Virus (HIV) Infections

    go.drugbank.com/conditions/DBCOND0035016
    Drugs: Cobicistat · Emtricitabine · Lamivudine · Stavudine · Zidovudine
  9. Pathway

    Efavirenz Action Pathway

    smpdb.ca/view/SMP0000740
    Drug action

    Efavirenz (also known as Sustiva) is a nucleoside reverse transcriptase inhibitor (NRTI) for treating HIV infection by inhibiting the transcriptase reversibly. Efavirenz is phosphorylated to its active triphosphorylated form so that it c...

    Drugs: Efavirenz
  10. Pathway

    Lamivudine Action Pathway

    smpdb.ca/view/SMP0000742
    Drug action

    Lamivudine (also known as 3TC) is an antiretroviral drug that can be used to treat HIV/AIDS. Lamivudine is phosphorylated to lamivudine triphosphate (L-TP), which is its active metabolite. Lamivudine triphosphate (L-TP) can bind and inhi...

    Drugs: Lamivudine