Chronic Hepatitis B Infection (DBCOND0058876)

Identifiers

Synonyms
Hepatitis B, Chronic (CHB) / Hepatitis B, Chronic / Hepatitis B chronic / Hepatitis B Chronic Infection / Hepatitis B, Chronic / Hepatitis B,Chronic / Chronic Hepatitis B / Chronic viral hepatitis B without delta-agent / Chronic type B viral hepatitis (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Adefovir dipivoxil
A nucleotide analog used to treat chronic hepatitis B.
Entecavir
A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
Interferon alfa-2a
A form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Interferon alfa-2b
A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma.
Lamivudine
A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
Peginterferon alfa-2a
A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Telbivudine
A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
Tenofovir alafenamide
A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
Tenofovir disoproxil
A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
Thymalfasin
Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate...
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00371761
PegIntron Versus Adefovir in the Treatment of Chronic Hepatitis B (CHB) e Antigen Positive Patients in Taiwan (P04498/MK-4031-278)treatment3completed
NCT03097952
"Real-life" Cohort Study on Patients With Chronic HBV Infection in JiangsuNo drug interventionsNot AvailableNot Availablerecruiting
NCT02995252
The HOPE Study: Characterizing Patients With Hepatitis B and CNot AvailableNot Availablerecruiting
NCT02612506
Safety and Pharmacokinetic Study of Hepalatide(L47) in Healthy VolunteersNo drug interventionstreatment1completed
NCT02967939
Efficacy and Safety of DA-2802 in Chronic Hepatitis B Patientstreatment3completed
NCT03018821
The Study of Two Different Chinese Traditional Medicine Treatment on Chronic Hepatitis BtreatmentNot Availableunknown_status
NCT03023787
Study of Hepalatide(L47) at Phase Ib in Healthy VolunteersNo drug interventionstreatment1completed
NCT04886102
Molecular Epidemiology of Hepatitis B in Cayenne General Hospital, French GuianaNo drug interventionsNot AvailableNot Availableunknown_status
NCT06128421
Individual Nutrition Support in HBV-ACLF Patients at Nutrition RiskNo drug interventionstreatmentNot Availablerecruiting
NCT02327702
Emtricitabine for Naive Chinese Pregnant Chronic Hepatitis B Patientstreatment4unknown_status
NCT02128503
Prevalence and Clinical Course of Chronic Hep B Infection in IBD and Rheumatologic DiseaseNo drug interventionspreventionNot Availableterminated
NCT01519921
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Positive Chronic Hepatitis B.treatment4completed
NCT00686790
Efficacy of Peginterferon Alfa-2b in Previously Untreated Subjects With Chronic Hepatitis B and D Co-infection (Study P04603)treatment3completed
NCT00230503
Dose-Ranging Study of Pradefovir in Patients With Compensated Hepatitis Btreatment2completed
NCT00230490
Open-label Treatment Extension Study for Patients Who Complete Study RNA200103-201treatment2terminated
NCT00111943
Safety and Acceptability of a Vaginal Microbicideprevention2completed
NCT06550128
Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Subjects With Chronic Hepatitis B (CHB).No drug interventionstreatment2recruiting
NCT06525909
A Real-world Study of Staging and Grading of Clinical Immune Status in Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablerecruiting
NCT06041022
A Non-invasive Model to Predict Antiviral Therapy in Gray Zone of Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05977283
HBsAg Declined Patients Follow-up StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05937178
Real-world Study Optimizing Nucleotide-analoguesNo drug interventionsNot AvailableNot Availablerecruiting
NCT05630807
Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 1)No drug interventionstreatment3active_not_recruiting
NCT05473806
Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Type 2 Diabetestreatment4unknown_status
NCT05382013
Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS Treatmentprevention4recruiting
NCT05376124
Clinical Characteristics, Natural Outcome and Treatment Optimization of RefractoryNo drug interventionsNot AvailableNot Availablerecruiting
NCT05276297
A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapytreatment2active_not_recruiting
NCT05107778
Study to Evaluate Safety and Efficacy of ASC42 Combined With ETV and PEG-IFN α-2a in Subjects With HBVtreatment2completed
NCT04805034
Predictive Model for Prognosis of Chronic HBV Infection MothersNo drug interventionsNot AvailableNot Availableunknown_status
NCT04782375
Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis BNo drug interventionssupportive_care4active_not_recruiting
NCT04724785
Real World Study About Anti-viral Regimen Adjustment on Achieving Complete Response in CHB PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04538651
A Cross-sectional Study for Renal Function of Patients With Chronic Hepatitis B in ChinaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04465916
Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD)treatment2terminated
NCT04365933
A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavirtreatment2completed
NCT04211805
Maternal Therapy With TAF Versus TDF to Prevent Vertical Transmission of Hepatitis BNot AvailableNot Availableunknown_status
NCT04160897
Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated CirrhosisNot AvailableNot Availableunknown_status
NCT04133259
Evaluate the Efficacy and Safety of HLX10 in Chronic Hepatitis B Patientstreatment2unknown_status
NCT03772249
Study of Safety and Tolerability of DCR HBVSNo drug interventionstreatment1completed
NCT03485534
Evaluate the Efficacy and Safety to Tenofovir Disoproxil in Chronic Hepatitis B Patientstreatment4completed
NCT03681132
The Norwegian Nucleoside Analogue Stop StudyNo drug interventionstreatment4completed
NCT03125213
A Study Evaluating AL-3778 in Combination With Peginterferon Alpha-2a in Chronic Hepatitis B Subjectstreatment2withdrawn
NCT04856085
Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infectiontreatment2recruiting
NCT05242445
A Study of Cetrelimab in Participants With Chronic Hepatitis B Virus Infectionbasic_science1completed
NCT05123599
A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infectiontreatment1completed
NCT05550519
A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) TreatmentNo drug interventionsother0withdrawn
NCT03468907
The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuationprevention4completed
NCT03272009
Evaluation of the Safety and Pharmacology of EYP001 in HBV Subjectstreatment1completed
NCT03320616
EYP001a Food Effect Study in Subjects With Chronic Hepatitis B Virus (HBV) InfectionNo drug interventionstreatment1completed
NCT02766933
Cameroon Baptist Convention Health Board Chronic Hepatitis B Cohort StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02693652
A Study to Evaluate the Safety and Efficacy of Therapeutic Hepatitis B VaccineNo drug interventionstreatment1 / 2completed
NCT02631096
Study of ARB-001467 in Subjects With Chronic HBV Infection Receiving Nucleos(t)Ide Analogue TherapyNo drug interventionstreatment2completed
NCT02392598
A Hepatitis B With Hepatic Steatosis StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02498275
Effect of RO6871765 and RO7011785 on Immune Response With the Stimulation of Peripheral Blood Mononuclear Cells (PBMCs) in Chinese Healthy Volunteers and Chronic Hepatitis B PatientsNo drug interventionsNot AvailableNot Availableterminated
NCT02327416
A Prospective Clinical Trial in Chronic Hepatitis B Patients NAs (Nucleotides or Nucleosides) Experienced (Anchor Study)treatment3unknown_status
NCT02366247
Phase Ⅲ Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg-positive Chronic Hepatitis Btreatment3unknown_status
NCT02201407
An Observational Study in Participants With Chronic Hepatitis B (CHB) Receiving Therapy With Peginterferon Alfa-2a 40 Kilodaltons (kD) (PEGASYS) - The PRO B StudyNot AvailableNot Availablecompleted
NCT02167113
Collection of Samples for the Clinical Evaluation of the Aptima HBV (Hepatitis B Virus) Quant (Quantification) AssayNo drug interventionsNot AvailableNot Availablecompleted
NCT02065336
A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infectiontreatment2terminated
NCT01886300
An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive Chronic Hepatitis B in VietnamNo drug interventionsNot AvailableNot Availableterminated
NCT01855997
A Study to Collect Blood Biomarker Samples From Participants With Chronic Hepatitis B (CHB) Who Received Treatment With Pegasys (Peginterferon Alfa-2a) ± Nucleoside/Nucleotide AnalogueNot AvailableNot Availablecompleted
NCT01734018
An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive or HBeAg-Negative Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT01667432
An Observational Study of Peginterferon Alfa-2a (PEGASYS®) in Patients With HBeAg Positive or HBeAg Negative Chronic Hepatitis BNot AvailableNot Availablecompleted
NCT01475851
Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B With Poor Response to Other DrugsNo drug interventionstreatment3completed
NCT01376154
Special Drug Use Investigation for ZEFIX (Lamivudine) Tablet (HBV Cirrhosis)Not AvailableNot Availablecompleted
NCT01237496
Analysis of HBV-Specific Immune Response in Patients With HBeAg Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a (40KD)) - Immunology Sub-Study of ML18253treatment3completed
NCT01107483
Observe Change of Endotoxaemia and Related Mediators in Patients With Chronic Hepatitis B Virus (HBV) InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01086085
A Study of Peginterferon Alfa-2a [PEGASYS] in Patients With Chronic Hepatitis B Who Are HBeAg Positivetreatment4completed
NCT01023217
Entecavir Plus Adefovir in Lamivudine-Resistant Chronic Hepatitis B Patients Who Fail Lamivudine Plus Adefovirtreatment4completed
NCT00962975
A Study of Pegasys Monotherapy in Patients With Chronic Hepatitis B Who Have Participated in Previous Studiestreatment1completed
NCT00838071
Evaluation of Serum Levels and Pharmacokinetics of a New Hepatitis B Immune Globulin Following Liver Transplantationprevention3completed
NCT00800787
Nabi-HB Administered Subcutaneously in Patients With Hepatitis B Virus Post Liver Transplantationtreatment3withdrawn
NCT00718887
Suboptimal Responders to Adefovir Switching to Entecavirtreatment4completed
NCT00651209
A Single-arm Study Evaluating the Efficacy and Safety of Telbivudine With or Without add-on Tenofovir in Adults With HBeAg-positive Chronic Hepatitis B (CHB)treatment4completed
NCT00625339
Continuing Lamivudine Versus Switching to Entecavir in Patients Who Achieved Undetectable HBV DNAtreatment4completed
NCT00637663
Continuing Lamivudine Versus Switching to Entecavir in Patients Who Achieved Undetectable Hepatitis B Virus DNAtreatment4completed
NCT00537537
To Evaluate Antiviral Efficacy of Telbivudine in Hepatitis B Antigen Positive (HbeAg-positive) Compensated Chronic Hepatitis B (CHB)treatment4completed
NCT00403585
Study of Adefovir Dipivoxil for Korean Patients With Chronic Hepatitis B(CHB) Who Have Completed ADF 103814treatment4completed
NCT00120354
Long-Term Lamivudine Therapy for Chronic Hepatitis BNo drug interventionstreatment4completed
NCT00076336
Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosistreatment3completed
NCT04059198
Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virustreatment2terminated
NCT05182463
Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patientstreatment4recruiting
NCT06452693
A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis BNo drug interventionstreatment1 / 2not_yet_recruiting
NCT06216470
Vaccinal Effect of HBsAg Monoclonal Ab VIR-3434 in Chronic Hepatitis B Infection [VISION]treatment2recruiting
NCT06196632
Development and Validation of Models to Predict Functional Cure in Patients With CHB After Peg-IFN Based TherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06115993
A Study to Evaluate the Safety and Efficacy of AHB-137 in Healthy Participants and HBeAg-negative Chronic Hepatitis B (CHB) PatientsNo drug interventionstreatment1 / 2recruiting
NCT06023745
Study IL- 35 Level and Fibronectin Type Ⅲ Domain Containing Protein 5 \ Irsin (FNDC5 rs3480) Gene Variations in Chronic Hepatitis B.No drug interventionsNot AvailableNot Availablerecruiting
NCT06000657
The Efficacy and Safety of Switching to Vemliver Tab From Entecavir in Chronic Hepatitis B Patients Who Pretreated With EntecavirNo drug interventionstreatment4active_not_recruiting
NCT05922306
Efficacy of NA Combined With PEG-IFN-α2b in the Continuous Versus Pulsed Treatment of Patients With Chronic Hepatitis Btreatment0recruiting
NCT05708560
Relationship Between MAFLD and Liver Fibrosis Progression in Patients With Chronic Hepatitis B: a Multicenter Retrospective Cohort StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05630820
Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 2)No drug interventionstreatment3active_not_recruiting
NCT05398393
An Experimental Study on the Effect of Tenofovir Amibufenamide on Blood Lipid During Anti-HBV TreatmenttreatmentNot Availableunknown_status
NCT05391360
Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Studyother1completed
NCT05172453
Mother-to-child Transmission of HBV in ChinaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05168293
Effect of Entecavir Versus Tenofovir on HBV DNA Level in Peripheral Blood Mononuclear CellsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05057065
A Clinical Research on Disease Progression and Intervention of Chronic HepatitisBNo drug interventionsNot AvailableNot Availableunknown_status
NCT05045261
ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC DiscontinuationNo drug interventionstreatment2unknown_status
NCT05005507
A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infectiontreatment2terminated
NCT04597164
Combination of DPMAS and Low Volume PE for Patients With HBV Related ACLFNo drug interventionsNot AvailableNot Availableunknown_status
NCT04585165
User-friendly HIV Testing and Counseling ServicesNo drug interventionsNot AvailableNot Availablerecruiting
NCT04536532
Evaluation HEC121120 Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Studytreatment1 / 2terminated
NCT04289987
A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B VaccineNo drug interventionstreatment2completed
NCT04237376
Chronic HBV Infection in Pregnant Women Taking TAF to Prevent Vertical TransmissionNot AvailableNot Availableunknown_status
NCT04248426
A Phase 1 Double-Blinded Study for Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus Infectiontreatment1completed
NCT04225715
A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis Btreatment2completed
NCT04201808
Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Idestreatment4unknown_status
NCT04166266
Observatory of Efficacy and Safety of Bulevirtide in Patients With Chronic HBV/HDV Co-infectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT04129554
A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infectiontreatment2completed
NCT04070079
Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:treatment4unknown_status
NCT03932513
Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patientstreatment2terminated
NCT03866187
Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B InfectionNo drug interventionstreatment1 / 2active_not_recruiting
NCT03778567
Renoprotective Effects of Telbivudine in Chronic Hepatitis Btreatment4completed
NCT03759782
Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral Activitytreatment3unknown_status
NCT04684914
HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)No drug interventionstreatment2terminated
NCT04035837
The Clinical Cure Project of Chronic Hepatitis B in Chinatreatment4recruiting
NCT05423106
A Single and Multiple Ascending Dose Study of JNJ-64457744treatment1terminated
NCT05870969
Digitalized Surveillance Management for Liver Cancer Risk Population in Improving Eearly Diagnosis Efficancy in Chinese Population (dSEARCH)No drug interventionsNot AvailableNot Availablerecruiting
NCT05867056
Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV InfectionNo drug interventionstreatment1recruiting
NCT03469583
Drug Drug Interaction Study for EYP001 With Entecavirtreatment1completed
NCT03463369
A First-In-Human Study to Evaluate Safety, Tolerability, Reactogenicity, and Immunogenicity of JNJ-64300535, a DNA Vaccine, Administered by Electroporation-Mediated Intramuscular Injection, in Participants With Chronic Hepatitis B Who Are on Stable Nucleos(t)Ide Therapy and Virologically SuppressedNo drug interventionsother1completed
NCT03358108
A Prospective,Observational Follow-up Study of Nucleoside Treated Patients With Chronic Hepatitis B (OCEAN Study)No drug interventionsNot AvailableNot Availableunknown_status
NCT03300414
Biologic Basis of Liver Cancer From Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT03258710
A Study of Switching From Entecavir to Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis Btreatment4completed
NCT02826070
EFFORT Further Extension Studytreatment4unknown_status
NCT02956850
A Study in Healthy Volunteers and in Participants With Chronic Hepatitis B to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7020531No drug interventionstreatment1completed
NCT02974829
REALM China Extension StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02588937
Active Drug Comparative Trial to Evaluate the Antiviral Activity and Safety in Chronic Hepatitis B Patientstreatment4unknown_status
NCT02570191
A Study of PEGASYS (Peginterferon Alfa-2a [40KD]) in Patients With Hepatitis B e Antigen (HBeAg)-Negative Chronic Hepatitis B Virus (HBV)treatment4completed
NCT02482272
Compare Continuing Lamivudine Plus Adefovir or Adefovir Versus Switching to Entecavir Plus Adefovir in Patients With LAM-resistant Chronic Hepatitis Btreatment4unknown_status
NCT02605252
New Strategy Study of Functional Cure of Chronic Hepatitis BtreatmentNot Availableunknown_status
NCT02604355
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7020322 Following Oral Administration in Healthy Participants and Chronic Hepatitis B PatientsNo drug interventionsbasic_science1terminated
NCT02391805
A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infectiontreatment2completed
NCT02327715
Emtricitabine for Prevention of Vertical Transmission of HBV in Chinese Pregnant HBsAg Positive Patientsprevention4unknown_status
NCT02327676
Emtricitabine for Naive Child Chinese Chronic Hepatitis B Patientstreatment4unknown_status
NCT02267473
Hepatitis B Patients Under Oral Nucleos(t)Ide Treatment With Intermittent Assessment of Kidney FunctionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02224456
Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosistreatment4completed
NCT02129829
PROLIFICA - West African Treatment Cohort for Hepatitis BNot AvailableNot Availablecompleted
NCT02097004
Study of Therapeutic Vaccination With Intensified Schedule Plus Pegasys Dual Therapy on Chronic Hepatitis B Infectiontreatment4completed
NCT02081469
Prophylaxis of CHB Patients With Malignant Tumor Receiving ChemotherapyNo drug interventionshealth_services_research4completed
NCT01908660
Hepatic Safety of Currently Used Antiretroviral Regimens in Patients With Chronic Hepatitis Under Real Life ConditionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01787279
An Expanded Access Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Negative Chronic Hepatitis Btreatment4completed
NCT01730508
An Observational Study of Pegasys (Peginterferon Alfa-2a) in Chinese Patients With HBeAg Negative Chronic Hepatitis BNot AvailableNot Availablecompleted
NCT01706575
A Study of Pegasys (Peginterferon Alfa-2a) Added to Nucleos(t)Ide Analogue Treatment in Participants With HBeAg-Negative Chronic Hepatitis B Genotype D Showing Stable Hepatitis B Virus (HBV) Deoxyribonucleic Acid (DNA) Suppressiontreatment2completed
NCT01705704
A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT01641536
Tolerability, Immunogenicity and Efficacy of HB-110 Administered by Electroporation in Chronic Hepatitis B PatientsNo drug interventionstreatment1completed
NCT01697501
A Study Evaluating IL28B Polymorphism in Patients With HBeAg-Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML18253No drug interventionsother3completed
NCT01521975
A Two-year Study of Telbivudine in HBeAg Negative Hepatitistreatment4completed
NCT01456312
HBsAg Related Response Guided Therapytreatment4unknown_status
NCT01480284
Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B Untreated With Nucleic Acid AnalogueNo drug interventionstreatment3completed
NCT01353742
Lamivudine and Adefovir Dipivoxil Fixed Dose Combinationtreatment1completed
NCT01341106
Induction of Fibrosis Regression on Patients With Chronic Hepatitis B InfectionNot Available4terminated
NCT01310062
The Development of Diagnostic Biomarker Panels for Hepatitis and Liver CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT01311947
Hepatitis B Virus Mutants and the Therapeutic Effect of Peginterferon Alfa-2a in HBeAg-Positive Chronic Hepatitis BNot AvailableNot Availablecompleted
NCT01205165
An Open Label, Multi Centre Phase IV Study of Adefovir Dipivoxil in Korean Patients With Chronic Hepatitis B (CHB)treatment4completed
NCT01090531
Patients With Chronic Hepatitis B and Low Viremia Not Receiving Antiviral TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00940485
A Study of Combination or Sequential Treatment With PEGASYS (Peginterferon Alfa-2a) and Entecavir in Patients With HBeAg Positive Chronic Hepatitis Btreatment4completed
NCT00986778
Entecavir Plus Adefovir in Lamivudine-Resistant Patientstreatment4withdrawn
NCT00921180
Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Positive Chronic Hepatitis Btreatment4unknown_status
NCT00962533
EFFicacy Optimization Research of Telbivudine Therapytreatment4completed
NCT00962871
A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Bothtreatment1completed
NCT00922207
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Adefovir or Entecavir in Patients With HBeAg-Positive Chronic Hepatitis Btreatment4completed
NCT00927082
A Follow-Up Study to WV19432, to Evaluate Long Term Post-Treatment Effects of PEGASYS (Peginterferon Alfa-2a(40KD))in Patients With HBeAg Positive Chronic Hepatitis BNot Available4completed
NCT00917761
Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Negative Chronic Hepatitis Btreatment4unknown_status
NCT00895713
Efficacy and Safety of Intramuscular HBIG Grifols for the Prevention of Recurrence After Liver Transplantationprevention2completed
NCT00815464
A Single-Arm Study Evaluating the Efficacy of Liquid Acupuncture Therapeutics in Chronic Hepatitis BNo drug interventionstreatmentNot Availableunknown_status
NCT00823550
Antiviral Therapy in Hepatitis B Virus (HBV)-Related Advanced Liver Disease Patientstreatment4unknown_status
NCT00646503
Prospective Exploratory Study to Evaluate the Safety and Efficacy of Telbivudine in the Fifth Year of Treatment in Chinese Patients With Compensated Chronic Hepatitis Btreatment4completed
NCT00640588
Prospective Exploratory Study to Describe Hepatitis B Virus (HBV) Kinetics During Treatment With Telbivudineother3completed
NCT00614471
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Entecavir in Treatment-Naive Patients With HBeAg-Positive Chronic Hepatitis B.treatment4completed
NCT00487747
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Chronic Hepatitis B.treatment4completed
NCT00460850
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Lamivudine Resistant HBeAg-Negative Chronic Hepatitis B.treatment4terminated
NCT00410202
Entecavir Plus Adefovir Combination Therapy Versus Entecavir Monotherapy vs Therapy With Adefovir Plus Lamivudine for Chronic Hepatitis B Infected Subjects With Lamivudine-resistant Virustreatment3completed
NCT00363155
KRN7000 in Chronic Hepatitis Btreatment1 / 2completed
NCT00347009
Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosistreatment4completed
NCT00034359
Safety and Antiviral Activity Study of ACH-126,443 (Beta-L-Fd4C) in Treatment-naive Adults With Chronic Hepatitis B Virus Infectiontreatment2completed
NCT04023721
Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitortreatment2terminated
NCT02289300
A Study to Evaluate a Study Drug, DCB-BO1202, for Alleviating Liver Fibrosis in Liver Cancer PatientsNo drug interventionstreatment2withdrawn
NCT06550622
Improved Sensitivity Detection of Serum HBsAg and HBsAg ReversionNo drug interventionsNot AvailableNot Availablerecruiting
NCT06245291
Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infectiontreatment2withdrawn
NCT05484466
A Study to Evaluate the Efficacy and Safety of ZM-H1505R in Combination With ETV Compared With ETV Monotherapy in Patients With CHBtreatment2recruiting
NCT05470829
A Multiple-dose Study in Chinese Subjects to Evaluate Safety,Tolerability,PK and PD of ZM-H1505RNo drug interventionstreatment1completed
NCT05286216
The Effect of Education on Drug Compliance and Quality of Life in Hepatitis B PatientsNo drug interventionspreventionNot Availableunknown_status
NCT05275023
An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participantstreatment2completed
NCT05265026
Aerobic Exercise Training in Patients With Chronic Hepatitis B and Hepatic SteatosisNo drug interventionstreatmentNot Availablecompleted
NCT05177926
Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF)prevention4unknown_status
NCT04847440
A Study of Safety and Efficacy of ATI-2173 in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection and in Subjects With Hepatitis D Virus Coinfectiontreatment2terminated
NCT04780204
Effectiveness of Antiviral Treatment in Cirrhotic Patients With Low-level Hepatitis B Virus DNA Levelstreatment4recruiting
NCT04749368
Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) Infectiontreatment2completed
NCT04667104
A Study of JNJ-73763989, JNJ-56136379, Nucleos(t)Ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus Infectiontreatment2completed
NCT04507269
Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland Chinatreatment2completed
NCT04082338
Chronic HBV Management for Asian AmericanNo drug interventionspreventionNot Availablecompleted
NCT03982186
A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infectiontreatment2completed
NCT03977857
Prediction Model Based on Computed Tomography Liver Volume for the Short-term Mortality in Hepatitis B Related Acute-on-ChronicNo drug interventionsNot AvailableNot Availablecompleted
NCT03539016
Observational Study on Pregnant Women With Chronic Hepatitis B and Their InfantsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05328427
Discontinuation of Antiviral Therapy as a Strategy to Cure Hepatitis BNo drug interventionsotherNot Availablenot_yet_recruiting
NCT05612581
A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infectiontreatment1 / 2active_not_recruiting
NCT04439539
A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infectiontreatment2completed
NCT04426968
A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis Btreatment2completed
NCT03164889
Clinical and Basic Research of ETV Plus GM-CSF in Chronic Hepatitis B PatientstreatmentNot Availableterminated
NCT03471624
Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF)treatment4completed
NCT03459768
Cohort Study on People Who Inject Drugs in SenegalNo drug interventionsNot AvailableNot Availableunknown_status
NCT03350074
HBV Envelope Proteins Variability on HBs Antigen Clearance Under Nucleos(t)Ide Analogue TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT02726789
Combination Treatment With REP 2139-Ca and Pegasys in Patients With Chronic Hepatitis Btreatment2completed
NCT02791269
A Study of Peginterferon Alfa-2a in Participants With Chronic Hepatitis B Virus (HBV) in an Expanded Access Programtreatment4completed
NCT02826018
A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) InfectionNo drug interventionstreatment1terminated
NCT02876419
A Long Term Follow-up Study of Patients From the REP 301 ProtocolNo drug interventionsNot AvailableNot Availablecompleted
NCT02952924
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participantstreatment1completed
NCT02719808
Study of Antiretroviral Therapy to Prevent HBV Intrauterine InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02646189
Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patientstreatment1 / 2completed
NCT02646163
Therapeutic Safety and Efficacy of REP 9AC (REP 2055) in HBV or HCV Infected PatientsNo drug interventionstreatment1 / 2completed
NCT02600117
Use of TDF in Patients With Inactive Chronic Hepatitis B Infectiontreatment3completed
NCT02598063
A Study to Evaluate Efficacy and Safety of Peginterferon Alfa-2a (Pegasys) and Adeforvir Dipivoxil (ADV) in Participants With Lamivudine-Resistant Hepatitis B e Antigen (HBeAg)-Positive Chronic Hepatitis Btreatment4completed
NCT02604823
A Study of Peginterferon Alfa-2a (Pegasys) in Participants With Hepatitis B E-Antigen (HBeAg)-Positive Chronic Hepatitis B Virus (HBV)treatment4completed
NCT02510963
Optimal Time for Tenofovir Treatment of Anti-Hepatitis B Virus (HBV) During the PregnancytreatmentNot Availableunknown_status
NCT02499562
A Phase II Clinical Trial of Hydronidone Capsules(F351) in Patients With Liver Fibrosis Induced by HBV Chronic Hepatitistreatment2completed
NCT02338674
TDF and LdT in Immune-tolerant CHB Patients Awaiting Assisted Reproductiontreatment1 / 2completed
NCT02327663
Emtricitabine for Naive Chinese Chronic Hepatitis B Patientstreatment4unknown_status
NCT02327689
Emtricitabine Plus Adefovir Dipivoxil for Naive Chinese HBV Related Cirrhosis Patientstreatment4unknown_status
NCT02360592
Combination Therapy With Interferon Plus Interleukin 2 and Hepatitis B Vaccine in Chronic Hepatitis B Patientstreatment4completed
NCT02366208
Phase II Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg Positive Chronic Hepatitis Btreatment2completed
NCT02195518
Tenofovir Disoproxil Fumarate (TDF) 300mg 3 Years RD Therapy Chinese Chronic Hepatitis B (CHN) CHB Multiple Nucleos(t)Ide Analogues (NAs) Failure Points Pts PH4 PMS Studytreatment4completed
NCT02148562
Assessment of Hepatitis B Virus Intra-host Population and Host-specific Immune Marker DiversityNo drug interventionsNot AvailableNot Availableunknown_status
NCT02075294
Efficacy and Safety Study of Adefovir and Entecavir for Elderly With Chronic Hepatitis BNot AvailableNot Availablecompleted
NCT01794234
An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis B Who Have Failed Antiviral Treatment With Nucleoside (Nucleotide) AnaloguesNo drug interventionsNot AvailableNot Availableterminated
NCT01641926
A Study of the Safety and Efficacy of Pegylated Inferferon Alfa-2b (PEG-Intron™) Versus Pegylated Interferon Alfa-2a (PEGASYS™) in Participants With Chronic Hepatitis B (P08450)treatment3terminated
NCT01645969
A Follow-Up Study of Patients With HBeAg Positive Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML22265No drug interventionsNot AvailableNot Availablecompleted
NCT01529255
EFFORT Extension Studytreatment4unknown_status
NCT01519960
A Study of Pegasys (Peginterferon Alfa-2a) Versus Untreated Control in Children With HBeAg Positive Chronic Hepatitis Btreatment3completed
NCT01480622
Pharmacokinetic (PK) Profiles of Tenofovir Disoproxil Fumarate (TDF) 300 mg in Healthy Chinese SubjectsNo drug interventionstreatment1completed
NCT01356901
Persistence, Adherence and Clinical Effectiveness of Entecavir in Chronic Hepatitis B PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01283074
An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HbeAg-negative Chronic Hepatitis B (Perseas)No drug interventionsNot AvailableNot Availablecompleted
NCT01220596
Efficacy Study of Sequential Therapy of Peginterferon Alfa-2a Following Entecavir in Patient With Chronic Hepatitis B.treatment3unknown_status
NCT01179594
A Study of 48 Versus 96 Weeks of Peginterferon Alfa-2a [Pegasys] Treatment, With or Without Entecavir, in Patients With Chronic Hepatitis B.treatment4withdrawn
NCT01163240
Epidemiological Study in Children and Adolescents With Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT01155427
Systematic Review of Antiretroviral Treatments for Chronic Hepatitis B (CHB)No drug interventionsNot AvailableNot Availablecompleted
NCT01128686
Lamivudine(LAM) Good Responder StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01095835
A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV)treatment3completed
NCT01013272
Lamivudine Therapy in Patients With Prior Entecavir Treatment and Undetectable Viral LoadtreatmentNot Availablecompleted
NCT01023230
A Study to Assess DV-601 in Subjects With Chronic Hepatitis Btreatment1completed
NCT01011738
An Observational Cohort Study in Patients With Chronic Hepatitis B Receiving PegasysNo drug interventionsNot AvailableNot Availablecompleted
NCT00860626
Early Response to Interferon Combined Short-Term Nucleoside Analogue Therapy in HBeAg(+) Chronic Hepatitis BNo drug interventionstreatmentNot Availableunknown_status
NCT00810524
Influence of Antiviral Treatment to the Long-Term Prognosis of Patients With Chronic HBV Infectiontreatment4unknown_status
NCT00661076
ADVANCE Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) + Adefovir Dipivoxil in Patients With Hbe(-) Chronic Hepatitis Btreatment3completed
NCT00710216
Comparison of Telbivudine Versus Lamivudine on the Early Dynamics and Kinetics of Viral Suppression in Chronic Hepatitis Btreatment4withdrawn
NCT00625560
Continuing Lamivudine vs Switching to Entecavir in Patients With Detectable HBV DNAtreatment4completed
NCT00536263
PegIntron Treatment of Chronic Hepatitis B e Antigen-Positive Patients (P05170/MK-4031-327)treatment3completed
NCT00512941
Laboratory Profile of Hepatitis B and C in Users of a Reference ServiceNo drug interventionsNot AvailableNot Availablecompleted
NCT00423891
A Study of Entecavir in Pediatric Patients With Chronic Hepatitis B Virus (HBV)-Infectiontreatment1 / 2completed
NCT00442572
SOFIA-LTT Study: A Study of Intermittent Long Term Treatment With PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Negative Chronic Hepatitis B (CHB).treatment2completed
NCT00435825
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB).treatment4completed
NCT00436163
A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) - Positive Chronic Hepatitis Btreatment4completed
NCT00410072
Entecavir Plus Tenofovir Combination Therapy Versus Entecavir Monotherapy in Naive Subjects With Chronic Hepatitis Btreatment3completed
NCT00395018
Antiviral Activity of Entecavir in Patients Receiving Liver Transplant Due to Chronic Hepatitis B Virus Infectionprevention3completed
NCT00154869
Peginterferon Alfa-2a Plus Ribavirin for Chronic Hepatitis C/Hepatitis B Co-Infection and Chronic Hepatitis Ctreatment3unknown_status
NCT05133856
A Study of TAF in Combination With PEG-IFN and Hepalatide in Subjects With Chronic Hepatitis Btreatment2not_yet_recruiting
NCT04288310
A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infectiontreatment2recruiting
NCT02937779
Tenofovir As Prevention Of Hepatitis b Mother-to-child Transmissionprevention4unknown_status
NCT01745822
Maternal Antiviral Prophylaxis to Prevent Perinatal Transmission of Hepatitis B Virus in Thailandprevention3completed
NCT01651403
Study to Evaluate the Antiviral Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate Versus Placebo in Pediatric Participants With Chronic Hepatitis B Infectiontreatment3active_not_recruiting
NCT03559790
Treatment Efficacy and Safety of TDF-TAF Switch Study in South KoreaNot AvailableNot Availableunknown_status
NCT05345990
Treatment of Patients With Chronic Hepatitis B With Hepatitis B Immunoglobulinstreatment2recruiting
NCT06573190
Liver Status and Presence of MASLD/MASH in Patients With Chronic Hepatitis BNot AvailableNot Availablecompleted
NCT00736190
A Study to Evaluate Tenofovir Disoproxil Fumarate (DF) in Asian-American Adults With Chronic Hepatitis B Infectiontreatment4completed
NCT04465890
A Phase II Study of Subcutaneously Injected PD-L1 Antibody ASC22 in Chronic Hepatitis B Patientstreatment2active_not_recruiting
NCT01694264
Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFαprevention3terminated
NCT04980664
Effort to Narrow the Gap Between in Accordance With Guidelines and Consent to Treat CHB Population in East of ChinaNo drug interventionsotherNot Availableunknown_status
NCT04997564
The Efficacy and Safety of 12-week SOF/VEL Regimen Combined With Prophylactic Use of TAF for Treatment-naïve Genotype 1-6 HCV/HBV Co-infection Adult Patients With or Without Compensated Cirrhosis in Chinatreatment4unknown_status
NCT04182321
Metformin as Add-on to the Standard Therapy in Patients With Chronic Hepatitis BtreatmentNot Availablecompleted
NCT05771402
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)No drug interventionstreatment4not_yet_recruiting
NCT02365402
Efficacies of Entecavir Add on HBeAg Negative Patients With HBV DNA Positive During Peginterferon Alpha 2a Treatmenttreatment4unknown_status
NCT00605384
A Phase IIIb Study to Compare Entecavir Plus Tenofovir vs. Adefovir Added to Continuing Lamivudine Therapy in Adult Patients With Lamivudine-Resistant Hepatitis B Infectiontreatment3terminated
NCT02387684
Efficay of Extended Peginterferon Alpha 2a Treatment in HBeAg Negative Chronic Hepatitis B PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05956379
Chronic Hepatitis B Patients With Concurrent MAFLD: Cohort Study and Exercise Intervention.No drug interventionstreatmentNot Availableenrolling_by_invitation
NCT01524679
Peg-interferon ADDed to an Ongoing Nucleos(t)Ide Based Treatment in Patients With Chronic Hepatitis B to Induce Decrease of HBs-Antigentreatment2completed
NCT01360879
Assessment of Liver FIBROsis by Real-time Tissue ELASTography in Chronic Liver DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01242787
Long-term Safety and Efficacy Study of LB80380 in the Treatment-naive Patients of Chronic Hepatitis Btreatment2unknown_status
NCT01813487
Study of the Immunogenicity and Efficacy of HBsAg Vaccine in Combination With Standard Antiviral Therapy With HB110EtreatmentNot Availablecompleted
NCT05310487
Phase 1 Study of 162, a Novel Neutralizing Antibody Targeting Hepatitis B Surface Antigen, in Healthy Adult SubjectsNo drug interventionstreatment1completed
NCT06092333
VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis Btreatment2not_yet_recruiting
NCT02581033
Determinants of Virological Response After Discontinuation of Nucleoside Analogue Therapy in Hepatitis B PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT01192854
An Study of Efficacy and Safety of Clevudinetreatment3completed
NCT01533051
Prospective Observational Cohort Study for the Durability of Anti-viral Therapy in Patients With Chronic Hepatitis BNo drug interventionsNot AvailableNot Availableunknown_status
NCT02355951
Non-investigational Study to Evaluate Adenovirus Serotype 5 (Ad5) Neutralizing Antibodies (nAb) in Patients With Chronic Hepatitis B Virus (HBV) Mono-infectionNo drug interventionsscreeningNot Availablecompleted
NCT01380951
Safety and Efficacy of Telbivudine on Liver Cirrhosis in Patients With Chronic Hepatitis B (CHB)treatment4unknown_status
NCT03434353
Study to Evaluate the Safety and Antiviral Activity of Inarigivir Soproxil (Formerly: GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB)treatment2terminated
NCT06085053
A Clinical Trial of TQA3038 Injection in Healthy Adult SubjectsNo drug interventionstreatment1recruiting
NCT00023153
Lamivudine and Adefovir to Treat Chronic Hepatitis B Infection in People With and Without HIV Infectiontreatment3completed
NCT00354653
A Trial To Study The Effect Of Lamivudine In Adult Patients Who Suffer From Chronic Hepatitis B Alonetreatment4completed
NCT02822547
Study on Treatment of Pegylated Interferon Alfa 2a(Pegasys®) in the Korean Chronic Hepatitis B(CHB) Adultstreatment4unknown_status
NCT04112147
A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis Btreatment2unknown_status
NCT00226447
Different Regimens of Pegylated Interferon and Lamivudine Combination Therapy in Chronic Hepatitis B Patientstreatment2completed
NCT04781647
A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus Infectiontreatment2terminated
NCT00048945
Efficacy and Safety Study of Pegasys in the Treatment of Chronic Hepatitis Btreatment3completed
NCT04431245
Stopping Antiviral Treatment in Chronic Hepatitis BNot AvailableNot Availableactive_not_recruiting
NCT00467545
An Extension to Viral Kinetics Study of Telbivudine and Entecavir in Adults With Chronic Hepatitis Btreatment4completed
NCT05828745
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB06-036 in Subjects With Chronic Hepatitis BNo drug interventionstreatment1 / 2recruiting
NCT05961098
A Study of RBD1016 in CHB ParticipantsNo drug interventionstreatment2recruiting
NCT00142298
Telbivudine in Adults Previously Treated in Idenix-Sponsored Telbivudine Studiestreatment3completed
NCT00781105
Efficacy and Safety of Telbivudine 600mg Tablets in Chinese Patients With Chronic Hepatitis Btreatment4completed
NCT01594905
Entecavir Plus Tenofovir Combination in Subjects With Multi-drug Resistant Chronic Hepatitis B Virus Infectiontreatment4unknown_status
NCT00116805
A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Positive Chronic Hepatitis Btreatment3completed
NCT04277897
A Study to Investigate the Safety, Tolerability, Pharmacokinetics of Single and Multiple Doses of Hepenofovir Fumarate Tablets in Healthy Volunteers.No drug interventionstreatment1unknown_status
NCT05357183
The Study on Clinical Outcome and Treatment Optimization of Chronic Hepatitis B Patients With HypoviremiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02452528
Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B Virustreatment2terminated
NCT04646928
Study of Entecavir for Reducing the Risk of Hepatocellular Carcinoma in Chronic Hepatitis B PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06295328
From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patientstreatment1 / 2recruiting
NCT01928511
Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapytreatment4completed
NCT04423393
Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infectiontreatment1completed
NCT00042393
An Open-Label Program of Adefovir Dipivoxil in the Treatment of Patients With Lamivudine-Resistant Chronic Hepatitis B With Limited Treatment OptionsNot AvailableNot Availableapproved_for_marketing
NCT06047093
Fine Needle Aspiration (FNA) Evaluation of the Intrahepatic HBV Reservoir and Its Immunological Characteristics in Chronically HBV-infected Patientsbasic_scienceNot Availablerecruiting
NCT05466071
Safety and Efficacy of TAF to Prevent MTCT of HBV in Middle/Late Pregnancies With High HBV DNA LoadNo drug interventionsNot AvailableNot Availablerecruiting
NCT05792878
Study of COVID-19 Infection and Its Clinical Prognosis in Chronic Hepatitis B Patients With Antiviral TherapyNot AvailableNot Availablerecruiting
NCT00869778
Phase 2 Trial of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis BNo drug interventionstreatment2completed
NCT02069678
Serum Hepatitis B Surface Antigen Levels to Guide the Stopping of Entecavir in HBeAg-negative Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT01270178
Entecavir for Chronic Hepatitis B in Hepatocellular Carcinoma Patients Underwent Radiofrequency Ablation TherapyNot AvailableNot Availableunknown_status
NCT02792088
Study to Assess the Antiviral Activity and Safety Endpoints for the Treatment of Besifovir 150mg Compared to Tenofovir 300mg in Chronic Hepatitis B Patients Who Have Resistance to Nucleoside Analoguestreatment3completed
NCT03672188
Study of VIR-2218 in Healthy Subjects and Patients With Chronic Hepatitis Btreatment1 / 2completed
NCT01926288
Efficacy and Safety of Entecavir Maleate Tablets in Chinese Patients With Hepatitis Btreatment4completed
NCT02249988
Clinical Efficacy of ABX203 Therapeutic Vaccine in HBeAg Negative Patients With Chronic Hepatitis Btreatment2 / 3completed
NCT01872988
Tenofovir Antiviral Therapy Following Transarterial Chemoembolization for HBV Related Hepatocellular Carcinomatreatment3terminated
NCT04507607
Efficacy and Safety of TAF in Pregnant Women With Chronic Hepatitis B Infectionhealth_services_research0unknown_status
NCT02505009
Efficacy of HBV Vaccine in Consolidation of Nucleos(t)Ide Analogues Therapytreatment4completed
NCT01911156
Sustained Off-treatment Response After HBeAg Loss in Chronic Hepatitis B Patients Treated With Nucleos(t)Ide AnaloguesNo drug interventionstreatment4unknown_status
NCT04672915
Prevalence of Occult Hepatitis B Virus Infection(OBI) in Subjects With Chronic Hepatitis B(CHB) Family HistoryNo drug interventionsNot AvailableNot Availableunknown_status
NCT00715715
Efficacy Study of Prednisone Priming to Treat Asian Chronic Hepatitis B PatientstreatmentNot Availablewithdrawn
NCT02774837
Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis Btreatment4unknown_status
NCT01831037
The Regression of Liver Fibrosis and Risk for Hepatocellular Carcinoma (ROLFH) StudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04536337
A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjectstreatment1recruiting
NCT00225537
4-Methylumbelliferone as a Treatment for Chronic HBV/HCVtreatment2unknown_status
NCT03215732
Cross Sectional Survey on the Burden and Impacts of Chronic Hepatitis B in the Rural Area of Niakhar, SenegalNo drug interventionsNot AvailableNot Availablecompleted
NCT02589652
Switch or Sequential Combination Therapy of Peginterferon in Hepatitis B Patients With Longterm Entecavir TherapyNot AvailableNot Availableunknown_status
NCT01401400
Genetic Study of Peginterferon Treatment in Hepatitis B Patients: The GIANT-B StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02965859
The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis Btreatment2unknown_status
NCT00597259
Pegasys Plus Entecavir Versus Entecavir Alone for Hepatitis Be Antigen-Positive Chronic Hepatitis Btreatment4unknown_status
NCT06263959
A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis BNo drug interventionstreatment2recruiting
NCT04032275
Correlation Between Virus and Biochemical Characteristics and Liver Histological Damage in Untreated Chronic HBV InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT00857675
A Efficacy and Safety Study of Adefovir Dipivoxil to Treat Chinese Patients With HBeAg+ve Chronic Hepatitis BNo drug interventionstreatment3completed
NCT04891770
Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)treatment2completed
NCT00307242
Study Comparing the Safety of Switching From Lamivudine to Adefovir Dipivoxil Versus Overlapping Lamivudine and Adefovir Before Adefovir Dipivoxil Monotherapy in Patients With Chronic Hepatitis Btreatment4completed
NCT00131742
Telbivudine Versus Lamivudine in Chinese Adults With Compensated Chronic Hepatitis Btreatment3completed
NCT05435599
Serum Regucalcin Level and Chronic Hepatitis BNo drug interventionsdiagnosticNot Availablecompleted
NCT03173599
The Safety and Tolerability of Metacavir Enteric-coated Capsules in Healthy Adult Volunteerstreatment1completed
NCT04157699
An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Tenofovir in Naive Patients With Chronic Hepatitis btreatment2unknown_status
NCT01937806
Phase 3 and Extensional Study of Besifovirtreatment3unknown_status
NCT06357806
The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB PatientstreatmentNot Availablerecruiting
NCT05871749
Effects of Hepatic Fibrosis on Hepatic Steatosis Using the Ultrasound Attenuation Imaging in Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT02560649
An Exploratory Study of RGT Strategy on Optimal NUC-experienced Patientstreatment4unknown_status
NCT00645736
CHARM: Chronic Hepatitis B Antihepadnaviral Resistance Mutation StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02049736
Effect of Telbivudine on Renal Function and Proteinuria in Patients With CHB & Chronic Renal DiseasestreatmentNot Availablewithdrawn
NCT03038113
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of RO7062931in Healthy Volunteers and Subjects With Chronic Hepatitis BNo drug interventionsbasic_science1completed
NCT02979613
Study to Evaluate Efficacy and Safety of Switching From TDF to TAF in Adults With Chronic Hepatitis B Who Are Virologically Suppressedtreatment3completed
NCT01965418
A Clinical Evaluation on Traditional Chinese Medicine Diagnosis and Treatment Program Blocking and Reversing Hepatitis B-related Liver Fibrosis - a Randomized, Controlled, Double-blind, Multi-center Clinical TrialNo drug interventionstreatment4unknown_status
NCT02894918
A Study to Evaluate Addition of Peginterferon Alfa-2a to Chronic Hepatitis B (CHB) Patients Treated With NAstreatment4unknown_status
NCT05853718
Study of Tenofovir Alafenamide in HBV-Infected Pregnant Womentreatment4recruiting
NCT00973219
Hepatitis B Surface Antigen(HBsAg) Loss in Chronic Hepatitis B Patients With Low Viral LoadtreatmentNot Availablecompleted
NCT00409019
Trial of Telbivudine Combination Therapy vs. Continued Adefovir Monotherapytreatment4withdrawn
NCT04939441
Regression of Liver Fibrosis by Tenofovir Alafenamide (TAF)treatment4active_not_recruiting
NCT05705141
The Effect of Metabolic Syndrome on Antiviral Response in People With Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05637541
Evaluation of The Safety, Efficacy and Pharmacokinetic Characteristics of GST-HG141 TabletsNo drug interventionstreatment2recruiting
NCT05423834
Chronic Kidney Disease Progression in Chronic Hepatitis B Patients on Tenofovir Alafenamide (TAF) Versus EntecavirNot AvailableNot Availableactive_not_recruiting
NCT03356834
Change of Renal Function and Bone Mineral Density in CHB Patients Switch From TDF to TAF vs. Maintaining TDFtreatment4recruiting
NCT06311734
A Study of LW231 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus InfectionNo drug interventionstreatment1active_not_recruiting
NCT03770624
A Study to Investigate the Safety, Efficacy and PK of Multiple Doses of QL-007 in Chronic Hepatitis B Patients in CHINANo drug interventionstreatment1unknown_status
NCT02474316
Combined Therapy With Peginterferon Alfa-2a With NA in NA-treated HBeAg Positive Patientstreatment4unknown_status
NCT05017116
A Single and Repeated Dose Escalation of RBD1016 in Subjects With Chronic Hepatitis B Virus (HBV) Infectiontreatment1completed
NCT00778596
Prednisolone Priming Study in Patients With Chronic Hepatitis Btreatment4unknown_status
NCT04069858
Maintaining Antiviral Efficacy After Switching to Generic Entecavir 1 mg for Chronic Hepatitis Btreatment4unknown_status
NCT03752658
TAF Real World Study for Universal EffectivenessNot AvailableNot Availableunknown_status
NCT05808335
A Study to Assess the Efficacy and Safety of Burfiralimab(hzVSF-v13) and OAD (Oral Antiviral Drug)No drug interventionstreatment2recruiting
NCT01935635
A Clinical Trial on HB-Vac Activated-DCs Combined With Peg-IFN or NAs in CHBtreatment1 / 2completed
NCT04485663
A Study of ALG-010133 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB SubjectsNo drug interventionstreatment1terminated
NCT02387463
Efficacy of Extended Peginterferon Alpha 2a Treatment in HBeAg Positive Chronic Hepatitis B PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01065363
Health Promotion and Management for Hepatitis B CarriersNo drug interventionspreventionNot Availableunknown_status
NCT05661786
Clinical Outcomes of HBeAg-negative CHB Patients With Indeterminate PhaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT01726439
Effectiveness of Nucleos(t)Ide Analogs (NUC) Therapy Among Naive CHB Patients in ChinaNo drug interventionsNot AvailableNot Availablecompleted
NCT01436539
Study of Effects and Safety Between Adefovir Dipivoxil Plus Polyene Phosphatidylcholine Versus Adefovir Dipivoxil Alone in Chronic Hepatitis B Patientstreatment4unknown_status
NCT03429439
Study on Effect of Intestinal Microbiota Transplantation in Chronic Hepatitis BNo drug interventionstreatmentNot Availableunknown_status
NCT02615639
A Clinical Trial on Hepatitis B Vaccine Activated-Dendritic Cells Combined With Anti-HBV Drugs in CHBtreatment1 / 2unknown_status
NCT04637139
A Study to Evaluate the Mass Balance Absorption and AME of VBRtreatment1completed
NCT03585322
APG-1387 Study of Safety, Tolerability ,PK/PD in Patients With Chronic Hepatitis Btreatment1completed
NCT01760122
Efficacy and Safety of Peginterferon Alfa-2b in HBeAg Positive Chronic Hepatitis Btreatment3completed
NCT05001022
A Study of ALG-020572 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single Doses in Healthy Volunteers and Multiple Doses in CHB SubjectsNo drug interventionstreatment1terminated
NCT00804622
Effects of Telbivudine and Tenofovir Disproxil Fumarate on the Kinetics of Hepatitis B Virus DNA in Chronic Hepatitis B (CHB)treatment2completed
NCT06289725
Impact of Hepatitis B Virus Genotype on Treatment Response in Children With Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablerecruiting
NCT01817725
Hepatitis B Vaccine in Chronic Hepatitis B Patients With Low Serum HBsAgtreatment1completed
NCT02899130
Effect of Polyherbal Formulation in Chronic Inactive Carriers of Hepatitis B VirusNo drug interventionstreatmentNot Availableunknown_status
NCT06364930
SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitustreatment4recruiting
NCT03109730
Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis Btreatment1 / 2completed
NCT05561530
A Study of ALG-125755 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single Doses in Healthy Volunteers, and Single and Multiple Doses in CHB SubjectsNo drug interventionstreatment1terminated
NCT02862548
Efficacy and Safety of Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF)-Containing Regimens in Participants With Chronic Hepatitis B Virus (HBV) Infection and Stage 2 or Greater Chronic Kidney Disease Who Have Received a Liver Transplanttreatment2completed
NCT06566248
A Clinical Trial to Evaluate the Efficacy and Safety of TQA3810 Tablets in Combination/Non Combination With Nucleoside (Acid) Analogues in Patients With Primary/Treated Chronic Hepatitis BNo drug interventionstreatment2recruiting
NCT04157257
An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Entecavir or Tenofovir in Patients With Chronic Hepatitis b Who Have Received Nucleoside (Acid) Therapytreatment2unknown_status
NCT02349126
Study of ARC-520 in Patient With Chronic Hepatitis B VirusNo drug interventionstreatment2withdrawn
NCT04864366
Efficacy and Safety of TAF for 48 Weeks in HBeAg Positive CHB PatientsNot AvailableNot Availableactive_not_recruiting
NCT01878565
The Treatment With HBIG+GM-CSF+HBV Vaccine for Chronic Hepatitis B Patients With HBeAg SeroconversionNo drug interventionstreatment1 / 2unknown_status
NCT00057265
A Randomized, Double Blind Trial of LdT (Telbivudine) Versus Lamivudine in Adults With Compensated Chronic Hepatitis Btreatment3completed
NCT01020565
A Study in Japan of the Safety and Antiviral Activity With Chronic Hepatitis B Infectiontreatment2completed
NCT00441974
Adefovir Dipivoxil For The Treatment Of Chinese Compensated Chronic Hepatitis B(CHB)Patientstreatment4completed
NCT04195074
Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis btreatmentNot Availablerecruiting
NCT05808374
Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis BNo drug interventionsbasic_science1recruiting
NCT05451420
Inactive HBsAg Carriers (IHCs) Treated With Pegylated Interferon α2b Based Intervention TherapyNo drug interventionstreatmentNot Availablecompleted
NCT01925820
Pegasys Plus Entecavir Versus Entecavir Versus Pegasys for Hepatitis B e Antigen-Negative Chronic Hepatitis Btreatment4unknown_status
NCT00226382
Treatment With Peginterferon Alfa-2a (40 KD) of Chronic Hepatitis B Patients, Who Have Failed Anti-viral Treatmenttreatment4completed
NCT02886182
Immune Function Status and the Prevalence of Hepatitis in Postpartum Pregnant Women With CHB InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT06368882
Efficacy and Safety of Antiviral Therapy With Peg-interferon for Chronic Hepatitis B Complicated With Nonalcoholic Fatty Liver Disease(OCEAN PROJECT)No drug interventionstreatment4recruiting
NCT04496882
Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside Analoguetreatment4unknown_status
NCT05905731
Autologous T-cells Transfected With mRNA Encoding HBV-TCR T Cell Therapy in Combination With NUC for Chronic Hepatitis BNo drug interventionstreatment1active_not_recruiting
NCT04718831
Spirulina (FEM-102) Supplement to Chronic Hepatitis B PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT02332473
A Prospective Study of Combination of Peginterferon Alfa-2b (40kD, Y-shape) and GM-CSF in Chronic Hepatitis Btreatment2completed
NCT02202473
Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjectstreatment4completed
NCT01204827
Follow Up of Patients Chronic Hepatitis B (CHB) Treated With Sebivo Using the 13C Methacetin Breath TestNo drug interventionsdiagnostic2 / 3withdrawn
NCT00536627
Efficacy and Tolerance of Naked DNA Vaccine in Patients With Chronic B HepatitisNo drug interventionstreatment1 / 2completed
NCT05763576
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus InfectionNo drug interventionstreatment1recruiting
NCT01148576
Influence of Hepatic Steatosis on the Therapeutic Effect of Entecavir in Chronic Hepatitis B Patientstreatment4unknown_status
NCT04102176
Halting Nucleoside Analogues in Chronic Hepatitis BNo drug interventionstreatmentNot Availableunknown_status
NCT04629976
Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis Btreatment1completed
NCT01198860
Treatment on HBeAg Positive or HBeAg Negative in Chronic Hepatitis BNot AvailableNot Availableapproved_for_marketing
NCT05317260
Steatohepatitis in Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT00798460
Efficacy of Clevudine Plus Lamivudine for Lamivudine-resistant Chronic Hepatitis B Patientstreatment4terminated
NCT01264094
A Study to Evaluate the Efficacy and the Change of sAg Levels in Chronic Hepatitis B Patients Receiving Clevudine Treatment Over the Long Periodtreatment4terminated
NCT00907894
Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis Bother1completed
NCT04846491
A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis Btreatment3completed
NCT02793791
Prophylactic Treatment of Hepatic Dysplastic Nodules in HBsAg Positive PatientsNo drug interventionspreventionNot Availableunknown_status
NCT01037062
An Open-Label Rollover Study of Entecavir (BMS-200475) in Adults With Chronic Hepatitis B Infectiontreatment2completed
NCT05753280
Effect of Serum Vitamin D Level on the Efficacy of Peg-interferon Treatment in CHBtreatment4completed
NCT00338780
Trial of Lamivudine Treatment in HBeAg Negative Chronic Hepatitis B Patients (in Asia)No drug interventionstreatment4completed
NCT01906580
Combination or Sequential Therapy of Peginterferon Alfa-2a and Entecavir for Patients With Chronic Hepatitis Btreatment4unknown_status
NCT03332329
Sequential/Combination Therapy in Nucleoside or Nucleotide Analogue (NA)-Suppressed Chronic Hepatitis B Patientstreatment4unknown_status
NCT00412529
Viral Kinetics Study of Telbivudine and Entecavir in Adults With Chronic Hepatitis Btreatment3completed
NCT01958229
Efficacy Study of Telbivudine in Chronic Hepatitis B PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00507689
Truvada Versus Truvada Plus Hepatitis B Immunoglobulin (HBIg) in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplantprevention2completed
NCT00035789
A Phase III Study of Entecavir vs Lamivudine in Adults With Chronic Hepatitis B Infection and Negative for Hepatitis B e Antigentreatment3completed
NCT01360892
Prediction of Incidence of Liver Cancer by Use of Real-time Tissue ElastographyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02412592
Sustained Viral Response in Chronic Hepatitis B Patients Who Achieved HBeAg Seroncongversion After Interferon TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00040144
Safety and Antiviral Study of ACH126, 433 (b-L-Fd4C) in Adults With Lamivudine-resistant Chronic Hepatitis Btreatment2terminated
NCT02533544
Treatment Efficacy and Safety of Tenofovir Disoproxil Fumarate (TDF) in naïve Chronic Hepatitis BNot AvailableNot Availablecompleted
NCT05238844
A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infectiontreatment2terminated
NCT05960240
Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.No drug interventionstreatment1recruiting
NCT03642340
A Post-marketing Surveillance to Assess Safety and Efficacy of BesivoNo drug interventionsNot AvailableNot Availableunknown_status
NCT05727267
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidatetreatment1recruiting
NCT01732367
TDF VS LAM + ADV in LAM + ADV Treated LAM-resistant CHB Patients With Undetectable Hepatitis B Virus DNAtreatment4completed
NCT00531167
Adding Adefovir Dipivoxil Versus Switching to Entecavir in Patients With Lamivudine-resistant Chronic Hepatitis Btreatment4completed
NCT01412567
Vaccine+HBIG Versus Vaccine+Placebo for Newborns of HBsAg+ MotherspreventionNot Availablecompleted
NCT05130567
A Study of LP-128 Capsules in Healthy SubjectsNo drug interventionstreatment1active_not_recruiting
NCT00988767
Safety and Immunogenicity of a Naked DNA-based Vaccine Therapy in Patients With Chronic Hepatitis BNo drug interventionstreatment1completed
NCT04454567
A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase Inhibitorstreatment2terminated
NCT01022801
A Phase II Dose Response Study in Japan in Chronic Hepatitis Btreatment2completed
NCT00071201
Evaluate Efficacy, Safety and PK of Adefovir Dipivoxil Liquid Suspension in Patients With Chronic Hepatitis Btreatment3completed
NCT01326546
Therapeutic Hepatitis B Vaccine (Mimogen-based) Joint Entecavir in Treating Chronic Hepatitis B Patientstreatment2completed
NCT03847246
Bioequivalence Study of Entecavir Tablets and Baraclude® Under Fasting Condition in Chinese Healthy VolunteerstreatmentNot Availablecompleted
NCT05286346
Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis Btreatment4completed
NCT02973646
Peginterferon Alfa-2b Treatment in HBeAg(+) Chronic Hepatitis b Patients Based on Interferon Gene Mutation and Receptor Detectiontreatment4unknown_status
NCT01588912
Efficacy of Telbivudine With or Without add-on Tenofovir According to Roadmap Strategy Compare With Entecavirtreatment4unknown_status
NCT00635310
Safety Profiles of Liver Biopsy in Hemodialysis Patients With Chronic Viral Hepatitis Pre-treated With VasopressinNo drug interventionsNot AvailableNot Availableunknown_status
NCT01026610
Safety and Efficacy Study of LB80380 in the Treatment-naive Patients of Chronic Hepatitis Btreatment2completed
NCT06323681
Pegylated Interferon α in Previously Interferon-treated CHB(Leading Study)No drug interventionstreatmentNot Availablerecruiting
NCT05760781
To Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis BNo drug interventionstreatment2terminated
NCT01464281
A Study of Switch From Nucleotide to Peginterferon Alfa-2a in CHB Patients Achieving HBeAg Loss and HBV DNA <200IU/mlNo drug interventionstreatmentNot Availableunknown_status
NCT00263614
Evaluation of Chronic HBV Patients w/Evidence of HBV Replication and Normal or Minimally Elevated Liver Transaminases.No drug interventionsNot AvailableNot Availablecompleted
NCT04896255
Long-term Outcomes of Anti-viral Therapies in Patients With Chronic Viral Hepatitis BNot AvailableNot Availablerecruiting
NCT06313255
A Retrospective Observational Study on the Effects of Probiotics on HBsAg ClearanceNo drug interventionsNot AvailableNot Availablerecruiting
NCT03905655
Study of Nitazoxanide Compared to Placebo in Subjects With HBeAG-Negative Chronic Hepatitis Btreatment2completed
NCT03253250
The Investigation of Peginterferon Alfa-2a on the RFS of the Subjects With HCC Who Have Been Treated by Resectiontreatment4unknown_status
NCT04674423
The Effectiveness and Safety of Tenofovir Alafenamide in the Treatment of Chronic Hepatitis B Patients With Mildly Elevated Alanine Aminotransferase and Significant Liver Injury.treatment4recruiting
NCT04301908
A Cohort Study on Long-term Clinical Outcomes of Antiviral Therapy in Patients With Chronic Hepatitis B and CirrhosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00036608
A Phase III Study of Entecavir vs Lamivudine in Chronic Hepatitis B Subjects With Incomplete Response to Lamivudinetreatment3completed
NCT03209908
The Study of Short-range Antiviral Treatment During Pregnancy to Block Mother-to-child Transmission of Hepatitis B Virus and Withdrawal TimeNot AvailableNot Availableunknown_status
NCT01834508
3E Extension Studytreatment4unknown_status
NCT03575208
Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis Btreatment2withdrawn
NCT03349008
Magnesium Isoglycyrrhizinate Followed by Diammonium Glycyrrhizinate and Combined With Entecavir in Chronic Hepatitis Btreatment4unknown_status
NCT00275938
Interferon Alpha 2b Plus Ribavirin for Chronic Hepatitis Btreatment2 / 3completed
NCT02805738
Clinical Trial to Evaluate the Efficacy and Safety of CKD-390 Tablettreatment3unknown_status
NCT01532843
Lowering Viral Load With Nucleos(T)Ide Analogues Prior to Peginterferon Treatment to Ncrease Sustained Response in CHBtreatment4completed
NCT03780543
A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patientstreatment2terminated
NCT05760703
Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis BNo drug interventionstreatment2terminated
NCT02167503
Observational Study on Patients With Chronic Hepatitis BNo drug interventionsNot AvailableNot Availableunknown_status
NCT02362490
Efficacy of Peginterferon Alpha 2a Therapy in Chronic Hepatitis B Patients Being Treated With Nucleoside(Acid) Analoguestreatment4unknown_status
NCT04643990
LDT Combined With TDF to Improve EGFR Decreasing in Patients With Chronic Hepatitis B Treated With TDFNo drug interventionsNot AvailableNot Availableunknown_status
NCT03308890
The Effect of Entecavir Consolidation on Post-TDF Treatment Durabilityother4unknown_status
NCT05147090
Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis Btreatment4recruiting
NCT00095121
Safety and Efficacy of Adefovir Dipivoxil in Children and Adolescents With Chronic Hepatitis Btreatment3completed
NCT04759521
Evaluation of Liver Fibrosis With 2D-Shear Wave ElastographyNo drug interventionsNot AvailableNot Availablecompleted
NCT03038802
A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infectiontreatment1 / 2not_yet_recruiting
NCT03214302
The Incidence of Postpartum Hepatitis in Pregnant Women With Chronic Hepatitis B Virus InfectiontreatmentNot Availableunknown_status
NCT02348502
Sustained Viral Response in Patients Achieved HBsAg Level≤100 IU/ml After Completed Interferon TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT01373684
PEG-interferon Alfa-2a add-on Study in HBeAg Negative Chronic Hepatitis B Patientstreatment4completed
NCT00393484
A Study in Korea of Entecavir Versus Lamivudine in Adults With Chronic Hepatitis B Infectiontreatment4completed
NCT01743079
Study of Telbivudine and Lamivudine to Prevent Vertical Transmission of Hepatitis Bprevention4completed
NCT01804387
Comparison of Telbivudine Plus Adefovir With Lamivudine Plus Adefovir for the Treatment of Lamivudine-resistant Chronic Hepatitis B at 52 Weeks: A Pilot Studytreatment4unknown_status
NCT01671787
A Phase 1b Study Assessing GS-7340 in Treatment-Naive Adults With Chronic Hepatitis Btreatment1completed
NCT02017587
Procurement of Blood Samples for a Biomedical Research Program on T Cell Functional Response to Chronic HBV InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT01769833
HBsAg Decline After Pegylated-interferon-α in e Antigen Positive Chronic Hepatitis B With Nucleoside Maintenancetreatment3unknown_status
NCT01595633
Switch From Adefovir to Tenofovir in Chronic Hepatitis B for Suboptimal Response to Adefovir-based Combination Therapytreatment4unknown_status
NCT03180333
The Tolerability and Pharmacokinetics Clinical Trial of Metacavir Enteric-coated Capsules in Healthy Adult Volunteerstreatment1completed
NCT00117533
Pegylated Interferon Alfa-2b Plus Ribavirin in Chronic Hepatitis B and Deltatreatment4unknown_status
NCT04464733
Safety, Tolerability, Pharmacokinetics(PK), Pharmacodynamics(PD) and Food Effect of HRS9950 in Healthy and CHB SubjectsNo drug interventionsother1unknown_status
NCT00035633
A Phase III Study of Entecavir vs Lamivudine in Adults With Chronic Hepatitis B Infection and Positive for Hepatitis B E Antigentreatment3completed
NCT01264133
A Study With Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis Btreatment4terminated
NCT01264354
An Open Study to Evaluate the Efficacy, Safety of Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis Btreatment4completed
NCT02738554
Off Treatment Durability in Chronic Hepatitis B With Good Immune ControlNo drug interventionsotherNot Availablecompleted
NCT06070051
Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide TherapyNo drug interventionstreatment1recruiting
NCT04202653
Combination of ETV, TQ-A3334 and TQ-B2450 for CHB (Neptune Study)treatment2unknown_status
NCT03491553
Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis Btreatment2completed
NCT04518553
Plasma Purification and Chronic Hepatitis BNo drug interventionstreatmentNot Availableunknown_status
NCT06457477
Sequential Combination Therapy With PD-1 Antibody and Peg-IFNα in CHB PatientstreatmentNot Availablerecruiting
NCT02523547
Study to Evaluate the Non-inferiority of Cavir in HBeAg(+)Chronic Hepatitis B Patients Treated With Baracludetreatment4unknown_status
NCT06184347
Population-wide Research for HBV-related Liver Diseases in Maoming CityNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02166047
Study To Evaluate Safety and Efficacy of Vesatolimod for the Treatment of Chronic Hepatitis B Virus in Virally-Suppressed Participantstreatment2completed
NCT02883647
Therapeutic Effects and Long-term Follow-up After Ending Nucleos(t)Ide Analogs Therapy in Chronic Hepatitis bNot AvailableNot Availableunknown_status
NCT00115245
Telbivudine Versus Adefovir Dipivoxil in Adults With HBegAg-Positive, Compensated Chronic Hepatitis Btreatment3completed
NCT01266005
A Study to Compare and Evaluate Intrahepatic cccDNA Reduction After Administrating Clevudine or Entecavir in the Chronic HBV Patientstreatment4terminated
NCT06221605
Regulation of Intestinal Flora by Compound Probiotics in Patients With Chronic Hepatitis BNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00146705
Long Term Follow-up of Pegylated-Interferon Alpha-2bNo drug interventionsNot AvailableNot Availablecompleted
NCT03734783
IL-35+Breg/Il-35 Effect on T Cell Immune in Patients With CHBNo drug interventionsNot AvailableNot Availablecompleted
NCT04551261
GLS4/RTV and TAF Drug-drug Interactionother1completed
NCT00324961
Adefovir Dipivoxil Tablets (10mg) In Chinese Subjects With HBe Antigen Negative Chronic Hepatitis Btreatment4completed
NCT04650828
TDF Combined With LDT for the Treatment of HBeAg-positive Hepatitis B Patients With Poor Response to TDF for 12 MonthsNot AvailableNot Availableunknown_status
NCT02594293
Pegylated Interferon(Peg-IFN) in Reducing Relapse Rate in Patients After Discontinuation of NUC Therapyprevention4completed
NCT04676893
Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-388 in Healthy SubjectsNo drug interventionstreatment1unknown_status
NCT00558493
Switching Study From Lamivudine to Clevudine in the Chronic Hepatitis B Patientstreatment4completed
NCT03577171
A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)treatment2completed
NCT03366571
Improvement of Hard Endpoint in Chronic Hepatitis B Patients Treated With Antiviral TherapyNot AvailableNot Availableactive_not_recruiting
NCT02125071
Study on the Pharmacokinetic Characteristics of I.V. Hepabig Injection Used for Prevention of Hepatitis B Relapse After Liver TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT06154278
Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis Bbasic_science2recruiting
NCT05189288
Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-388(2) in Healthy SubjectsNo drug interventionstreatment1completed
NCT02368288
Efficacies of Entecavir Add on HBeAg Positive Patients With HBV DNA Positive During Peginterferon Alpha 2a Treatmenttreatment4unknown_status
NCT02300688
Bioequivalence Study to Compare the Pharmacokinetics of Besifovir in Healthy Adult VolunteersNot Available1completed
NCT03439488
A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis BNo drug interventionsother1completed
NCT01264107
An Open Study to Evaluate the Sustained Effect in Patients Showing Virological Responses With Muscle-related Symptom of Chronic Hepatitis B Patients Who Received ClevudineNo drug interventionsNot AvailableNot Availablecompleted
NCT05282407
A phase4 Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis Btreatment4completed
NCT03181607
Efficacy and Adverse Effects of Nucleoside Analogues (TDF/LDT) in Preventing Mother-to-child Transmission of HBVNo drug interventionsNot AvailableNot Availableunknown_status
NCT00507507
A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT)treatment2completed
NCT04028856
Cohort Study of Efficacy and Safety of Interferon Intermittent Treatment of Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT02817685
Follow-up Strategy of Chronic Hepatitis B for Early Detection and Diagnosis of Hepatocellular Carcinoma: A Randomized Control TrialNo drug interventionsNot AvailableNot Availableunknown_status
NCT01829685
Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapytreatment4unknown_status
NCT03244085
A Study to Investigate the Safety, Efficacy and Pharmacokinetic Profile of Multiple Doses of QL-007 in Chronic Hepatitis B PatientsNo drug interventionstreatment1unknown_status
NCT01342185
Efficacy of Medical Ozone Therapy in Patients With Chronic Hepatitis BNo drug interventionstreatment3unknown_status
NCT05671315
A Prospective Study to Evaluate Peginterferon in Reducing the Incidence of HCC in CHB PatientstreatmentNot Availablerecruiting
NCT00936715
Rollover Protocol Continued Access to Emtricitabine/Tenofovir Disoproxil Fumarate for Adults in United Statestreatment2completed
NCT06130137
Gut Microbiome in People Living With HIV and HBVNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02401737
Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patientstreatment1completed
NCT05298332
Ethnobridging Study in Healthy Volunteers, Chinese and Japanese Subjectstreatment1terminated
NCT00199732
Evaluation of cccDNA and Total HBV DNA Kinetics in Lymphocytes, Total Blood and Serum in Chronic Hepatitis B Patients Treated With Adefovir Dipivoxil and Peg Interferon Alpha 2aNo drug interventionsNot AvailableNot Availablecompleted
NCT04539652
Clinical Trial to Evaluate the Efficacy and Safety of TenofoBell® Tablet in Chronic Hepatitis B PatientsNo drug interventionstreatment4completed
NCT01589952
Pegylated Interferon and Entecavir Combination in Chronic Hepatitis B (CHB)treatment1 / 2unknown_status
NCT03733652
Optimal Treatment for Poor Efficacy of Entecavir in Chronic Hepatitis B PatientstreatmentNot Availableunknown_status
NCT03714152
A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis BNo drug interventionstreatment1completed
NCT00132652
Switching Therapy From Lamivudine to Telbivudine Versus Continued Lamivudine in Adults With Chronic Hepatitis Btreatment3completed
NCT05721300
Study on Screening, Verification and Intervention of High-risk Patients With Liver CancertreatmentNot Availablerecruiting
NCT02428400
Safety and Tolerability of TG1050: A Dose-finding StudyNo drug interventionstreatment1completed
NCT04519359
Biomarkers Guided Stopping NAs TreatmentNo drug interventionspreventionNot Availableunknown_status
NCT05273775
A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteersbasic_science1completed
NCT01887275
A Control Study to Evaluate The Efficacy And Safety of Ozone-therapy in Chronic Hepatitis BNo drug interventionstreatment4completed
NCT04779970
COIN-B: COntrolled Interruption of Nucleos(t)Ide Analogue Treatment in Chronic Hepatitis B InfectionsNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02112799
Safety and Efficacy Study of NVR 3-778 in Healthy Volunteers and Hepatitis B Patientstreatment1completed
NCT06162299
A Phase I, The Study to Evaluate the Safety, Immunogenicity and Efficacy of YS-HBV-002No drug interventionstreatment1not_yet_recruiting
NCT02336399
Sustained HBsAg and Viral Response in Patients Achieved HBsAg Loss by Interferon TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT00606099
Efficacy and Safety of Telbivudine in Patients With Chronic Hepatitis Btreatment4withdrawn
NCT02862106
Second Stage:Open-label Study of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis BNo drug interventionstreatment2completed
NCT05766449
Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLDNo drug interventionsNot AvailableNot Availablerecruiting
NCT05483049
Prevalence of Significant Liver Fibrosis and Inflammation in Chronic HBV Infected Patients in Grey ZoneNo drug interventionsNot AvailableNot Availableunknown_status
NCT01063036
Efficacy and Safety Study of Entecavir Plus Tenofovir in Patients With Chronic Hepatitis B Who Failed Previous Treatmenttreatment3completed
NCT02364336
Add-on Peginterferon Following Nucleos(t)Ide Analogue Treatmenttreatment2completed
NCT05490836
Functional Cure Rate of Peg-IFNα-2b Combined With TAF in HBeAg Negative CHB PatientsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03032536
Study of the Relative Oral Bioavailability of AL-3778 Tablets and Drug Interaction With Entecavir or Tenofovir Disoproxil Fumarate in Healthy Volunteerstreatment1terminated
NCT02532413
Antiviral Efficacy of the Combination Treatment With Poly IC and Entecavir for Chronic Hepatitis Btreatment4unknown_status
NCT02031913
Prospective Cohort Study of Association of Insulin Resistance/Steatosis With Hepatic Fibrosis in CHB and NAFLDNo drug interventionsNot AvailableNot Availablecompleted
NCT02901418
A Study of the Interruption on the Mother-to-child Transmission of Hepatitis B Virus (HBV MTCT)in Newborns at High RiskNot AvailableNot Availableunknown_status
NCT00558818
Long-term Study With Clevudinetreatment4completed
NCT03792919
Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)treatment4recruiting
NCT00316719
Adefovir Dipivoxil In Compensated Chronic Hepatitis B Patientstreatment3completed
NCT03180619
Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV)treatment2completed
NCT02463019
Roll-over After 3-year Trial for Tenofovir in Mild Chronic Hepatitis Btreatment4unknown_status
NCT02565719
REP 2139-Mg and REP 2165-Mg Combination Therapy in Chronic Hepatitis B Infectiontreatment2completed
NCT03241641
Switching From TDF to TAF vs. Maintaining TDF in Chronic Hepatitis B With Resistance to Adefovir or Entecavir.treatment4completed
NCT05569941
A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-4334 in Healthy SubjectsNo drug interventionstreatment1completed
NCT06425341
A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis BNo drug interventionstreatment2recruiting
NCT06280534
Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy SubjectsNo drug interventionstreatment1recruiting
NCT04398134
A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infectiontreatment2terminated
NCT01597934
Antiviral Efficacy of Switching to ETV Plus TDFtreatment4unknown_status
NCT02893124
The Optimizing Treatment of Peginterferon (PEG IFN) Alpha in Chronic Hepatitis B Virus Patients With Low Level HBsAgtreatment4unknown_status
NCT04501224
The Efficacy and Safety of TAF vs Other NAs in Patients With LVLtreatmentNot Availableunknown_status
NCT05769816
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A)No drug interventionstreatment4not_yet_recruiting
NCT04083716
A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy AdultsNo drug interventionstreatment1completed
NCT00291616
Efficacy Study of Thymosin alpha1 & Pegylated Interferon-alpha2a to Treat Chronic Hepatitis BNo drug interventionstreatment4completed
NCT01546116
Adefovir and Lamivudine for Entecavir Resistance (ALTER Study)treatment4completed
NCT00970216
Study of Telbivudine in Chronic Hepatitis BNot AvailableNot Availablecompleted
NCT00895596
Safety and Efficacy Study of LB80380 in the Patients With Lamivudine-Refractory Chronic Hepatitis Btreatment1 / 2completed
NCT05905458
A Phase II Clinical Study of the Efficacy and Safety of HRS9950 Tablets in Chronic Hepatitis B Patients Who Are Virologically Suppressed on Nucleoside or Nucleotide Analogues (NAs)No drug interventionstreatment2active_not_recruiting
NCT05357235
The Study on Optimal Treatment and Clinical Outcome of Chronic Hepatitis B Patients With Inactive HypoviremiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01471535
HBsAg Clearance in Inactive Chronic HBsAg Carriers After Interferon TreatedtreatmentNot Availablecompleted
NCT01728935
Tenofovir in Asian Chronic Hepatitis B PatientstreatmentNot Availablecompleted
NCT05786963
Comparison of Hepatus and FibroScan for Evaluation of Fibrosis and SteatosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04412863
Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infectiontreatment2active_not_recruiting
NCT02908763
HBsAg Loss/Seroconversion in Low Replicative Chronic Hepatitis B Virus(HBV) Infection Patientstreatment4unknown_status
NCT00298363
Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine (FTC)/TDF, and Entecavir (ETV) in the Treatment of Chronic HBV in Subjects With Decompensated Liver Disease.treatment2completed
NCT04820686
A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infectiontreatment2terminated
NCT00221286
Efficacy and Safety of PegIFN +/- FTC / TDF to Treat Chronic Hepatitis B in HIV-Coinfected Patientstreatment3terminated
NCT06513286
TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidatetreatment1 / 2not_yet_recruiting
NCT05717686
A Study Evaluating AHB-137 in Healthy Participants and Participants With Chronic Hepatitis BNo drug interventionstreatment1active_not_recruiting
NCT05839639
A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With HBeAg-Negative Chronic Hepatitis B Treated With Nucleos(t)Ide Reverse Transcriptase InhibitorsNo drug interventionstreatment2completed
NCT00037622
Safety and Antiviral Study of ACH-126, 443 (Beta-L-Fd4C) in the Treatment of Adults With Chronic Hepatitis B Infection.No drug interventionstreatmentNot Availableterminated
NCT03357822
A Real-World Study of Pegylated Interferon In Nucleoside-treated Patients With Chronic Hepatitis Btreatment4unknown_status
NCT01522625
Tenofovir in Chronic Hepatitis B With Mild ALT Elevationtreatment4completed
NCT00140725
Lamivudine Plus Interferon Versus Lamivudine For The Treatment Of HBeAg Positive Chronic Hepatitis B Virus (HBV)treatment3completed
NCT02056548
Hepatitis B Virus Reactivation After Withdrawal of Preemptive Antiviral Therapy in Hematologic MalignancyNo drug interventionsNot AvailableNot Availableunknown_status
NCT05523648
Clinical Effects of Ganshuang Combined TDF to Treat CHB and NAFLDtreatment0completed
NCT06535048
Impact of Fatty Liver on Hepatitis B TherapyNot AvailableNot Availableactive_not_recruiting
NCT02566148
Life Course, HIV and Hepatitis B Among African Migrants Living in Ile-de-FranceNo drug interventionsNot AvailableNot Availablecompleted
NCT02589457
Study to Compare the Safety and Pharmacokinetics of CKD-390 Tablet With Viread® Tablettreatment1completed
NCT00001457
Lamivudine for Chronic Hepatitis Btreatment2completed
NCT05244057
A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patientstreatment2completed
NCT02863757
Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02287857
Efficacy and Safety of Domestic Tenofovir Tablets in Chinese Patients With Chronic Hepatitis BtreatmentNot Availableunknown_status
NCT01037166
Study in Japan of the Safety And Antiviral Activity in Adults With Chronic Hepatitis B Current Lamivudine Therapytreatment2completed
NCT03576066
A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infectiontreatment2completed
NCT01531166
A Cohort Study in Korean Patients With Chronic Hepatitis B (CHB) Receiving Pegylated InterferonNot AvailableNot Availablecompleted
NCT03615066
Study to Evaluate the Safety, Tolerability, and Antiviral Activity of Selgantolimod (Formerly GS-9688) in Viremic Adult Participants With Chronic Hepatitis B (CHB) Who Are Not Currently on Treatmenttreatment2completed
NCT01027065
Dose Escalation of Interleukin-1 (IL-7) Added on Antiviral Treatment and Vaccination in HBeAg-negative Chronic Hepatitis B Virus (HBV) Infected Patientstreatment1 / 2unknown_status
NCT01270165
Lamivudine Plus Adefovir Versus Telbivudine Plus Adefovir in Lamivudine Resistant Chronic Hepatitis Btreatment3unknown_status
NCT04543565
Pradefovir Treatment for the Patients With Chronic Hepatitis B Virus Infections: a Phase3 StudyNo drug interventionstreatment3recruiting
NCT00964665
Pharmacokinetic/Pharmacodynamic of Albinterferon Alfa-2b in Chronic Hepatitis B, eAg+, Infection Subjectstreatment1 / 2terminated
NCT00388674
Study of Entecavir in Patients With Chronic Hepatitis B Virus (HBV) InfectionNot AvailableNot Availablecompleted
NCT03753074
Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelinestreatment4active_not_recruiting
NCT05457920
Study on Clinical Program Optimization of Inactive Hepatitis B Surface Antigen (HBsAg) Carriers (IHCs)No drug interventionstreatmentNot Availablerecruiting
NCT02579382
Study to Evaluate the Safety, Tolerability, and Efficacy of Vesatolimod in Combination With Tenofovir Disoproxil Fumarate (TDF) in Adults With Chronic Hepatitis B (CHB) Infection Who Are Currently Not Being Treatedtreatment2completed
NCT04980482
Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infectiontreatment2active_not_recruiting
NCT06384131
A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus InfectionNo drug interventionstreatment1not_yet_recruiting
NCT02053727
Abatacept vs Placebo in RA Patients With Hepatitis B on Entecavir BackgroundtreatmentNot Availablewithdrawn
NCT02337127
Lamivudine Extending Therapy in Chronic Hepatitis B Patients After 3-year of Oral Antiviral Agentstreatment4unknown_status
NCT00117676
A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis Btreatment3completed
NCT05755776
The Efficacy and Safety of Tenofovir Amibufenamide to Treat Low-level Viraemia After Entecavir TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT03638076
The Safety, Antiviral Activity, and Pharmacokinetics of Morphothiadine Mesilate Capsulestreatment2completed
NCT00277576
Safety Study of HBV DNA Vaccine to Treat Patients With Chronic Hepatitis B InfectionNo drug interventionstreatment1completed
NCT01487876
Efficacy and Safety of Dual-plasmid Hepatitis B Virus DNA Vaccine in Chronic Hepatitis B PatientsNo drug interventionstreatment2unknown_status
NCT02174276
Safety and Efficacy of GS-4774 in Combination With Tenofovir Disoproxil Fumarate (TDF) for the Treatment of Participants With Chronic Hepatitis B (CHB) and Who Are Currently Not on Treatmenttreatment2completed
NCT00877760
Augmenting Response to Entecavir With Peginterferon a-2a for the Treatment of HBeAg-positive Chronic Hepatitis Btreatment4completed
NCT03108794
A Nation-wide Hospital-based Hepatitis B Registry:China Registry of Hepatitis BNo drug interventionsNot AvailableNot Availablerecruiting
NCT04480294
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of Oral HRS5091 in Healthy Subjects and Chronic Hepatitis B PatientsNo drug interventionsother1unknown_status
NCT02908191
A Study in Healthy Volunteers and Patients With Chronic Hepatitis Btreatment1completed
NCT01337791
Efficacy, Safety and Tolerability of Telbivudine in HBeAg Positive Chronic Hepatitis B Pregnant Women With Elevated Alanine Aminotransferase Levelstreatment4completed
NCT01267162
Long-term Study on Anti-HBV Effect of Tenofovir and Resistance Surveillance in Asian-American Adult PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04142762
A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adultstreatment1completed
NCT01143662
Efficacy and Safety of Ypeginterferon Alfa-2b in HBeAg Positive Chronic Hepatitis Btreatment2completed
NCT03740789
Evaluation of Antiviral Indications on Chronic HBV Infection With Different Transaminase LevelsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00307489
Treatment of Persistent Viremia (Virus in Blood) in Chronic Hepatitis B Subjects Already Receiving Adefovir Dipivoxiltreatment2completed
NCT01172392
A Randomized Study to Assess the Loss of HbsAg After a 48-week Treatment Period With Pegylated Interferon Alpha 2a in Patients With Chronic Hepatitis Btreatment3unknown_status
NCT04271592
A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adultstreatment1completed
NCT03448744
Efficacy and Safety of Combination Therapy of Thymalfasin and Entecavir in HBeAg-positive ETV-experienced Patientstreatment4unknown_status
NCT00883844
PEG-IFN in HBV Patients With Incomplete Response to NANo drug interventionstreatment4completed
NCT01997944
Recombinant Human Serum Albumin/Interferon alpha2a Fusion Protein Phase Ib Study in Chronic Hepatitis B Patientstreatment1 / 2completed
NCT00397540
The Effect of Viral Load on Intrahepatic Recurrence in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC)No drug interventionstreatmentNot Availablecompleted
NCT01711567
Tenofovir Disoproxil Fumarate vs. Entecavir in Chronic Hepatitis B Patients With Partial Virologic Response to Entecavirtreatment4completed
NCT01277601
Efficacy & Safety of Tenofovir Disoproxil Fumarate (TDF) Plus Peginterferon α-2a (Peg-IFN) Versus TDF or Peg-IFN Monotherapy in Chronic Hepatitis Btreatment4completed
NCT02745704
The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAgNo drug interventionstreatment4unknown_status
NCT05264272
Disease Loads and Status of TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT02569372
A Phase 1 Study of GC1102 (Recombinant Hepatitis B Immunoglobulin) in Chronic Hepatitis B Patientstreatment1completed
NCT03662568
A Drug-drug Interaction (DDI) Study of Morphothiadine Mesilate/Ritonavir in Healthy Subjectstreatment1completed
NCT05793268
Finite Versus Continuous Nucleos(t)Ide Analogues for Chronic Hepatitis BtreatmentNot Availableactive_not_recruiting
NCT00513968
Phase I Study to Investigate the Safety and Efficacy of HBV DNA Vaccinetreatment1completed
NCT01679769
Prospective Study In Noninvasive Evaluation of Hepatic Fibrosis in Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT03777969
Prediction System of Clinical Endpoint Events for Chronic Hepatitis B PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02838810
The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAgNo drug interventionstreatment4unknown_status
NCT01260610
Randomized Controlled Study of Tenofovir Plus Telbivudine Versus Monotherapy With Either Drug in HBeAg Negative Chronic Hepatitis B PatientstreatmentNot Availablewithdrawn
NCT05414981
A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H3733 in Subjects With Chronic Hepatitis B Virus InfectionNo drug interventionstreatment1completed
NCT03042481
Off-therapy Response After Stopping Entecavir or TenofovirNo drug interventionsNot AvailableNot Availableunknown_status
NCT05343481
Efficacy of VTP-300 in Chronic Hepatitis B Infectiontreatment2recruiting
NCT01243281
Pegylated Interferon Alpha-2b Monotherapy Versus Combination With Entecavir in HBeAg-negative Chronic Hepatitis BtreatmentNot Availableunknown_status
NCT02258581
Long Term Follow-up Registry of Individuals Treated in A Gilead-Sponsored Trial in Individuals With Chronic Hepatitis B InfectionNot AvailableNot Availableterminated
NCT05841095
Evaluation of the Novel Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104No drug interventionstreatment1 / 2recruiting
NCT02476695
FibroTouch Non-invasive Evaluation of Liver Fibrosis and CirrhosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01491295
Switch to Tenofovir Versus Continue Lamivudine/Adefovir Treatment in Lamivudine-resistance Chronic Hepatitis B Patientstreatment4unknown_status
NCT05770895
Study of HBV Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis BNo drug interventionstreatment1active_not_recruiting
NCT01776814
Comparison of the Efficacy of Entecavir and Tenofovir Monotherapy for the Treatment of Nucleos(t)Ide-naïve Patients With Chronic Hepatitis B in KoreaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05295914
Performance of Novel Simplified Score for Chronic Hepatitis B Treatment Eligibility in ThailandNo drug interventionsNot AvailableNot Availableunknown_status
NCT05797714
The Effectiveness and Safety of TMF in the Treatment of Chronic Hepatitis B Patients With Normal ALT.treatmentNot Availableactive_not_recruiting
NCT06150014
A Clinical Study of TQA3605 Tablets Monotherapy or in Combination With Nucleoside (Acid) Analogues in Treatment Naive and Treated Patients With Chronic Hepatitis Btreatment1 / 2recruiting
NCT02263755
Establishment of Retrospective and Prospective Multicenter Cohort for Chronic Hepatitis BNo drug interventionsNot AvailableNot Availablecompleted
NCT02932150
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus InfectionNo drug interventionstreatment2recruiting
NCT04850950
Tenofovir Alafenamide to Prevent Perinatal Transmission of Hepatitis Bprevention4unknown_status
NCT04180150
A Study of TQ-A3334 Combined With Entecavir in the Treatment of Chronic Hepatitis Btreatment2unknown_status
NCT04139850
The Establishment of Korean Hepatitis B Patients CohortNot AvailableNot Availablerecruiting
NCT01627223
Comparison Between Lamivudine and Entecavir Treatment in Spontaneous Severe Acute Exacerbationtreatment4terminated
NCT02058108
Study of Efficacy and Safety, Tolerability and Pharmacokinetics of Telbivudine in Children and Adolescents With Compensated Chronic Hepatitis B Virus Infectiontreatment3terminated
NCT02881008
Myrcludex B vs Entecavir in Patients With HBeAg Negative Chronic Hepatitis Btreatment1 / 2completed
NCT01379508
Telbivudine or Tenofovir Treatment in HBeAg-negative Chronic Hepatitis B Patients Based on the Roadmap Concepttreatment4completed
NCT01374308
NASVAC Phase-III Trial in Chronic Hepatitis B (CHB) Patientstreatment3unknown_status
NCT06431438
Study to Evaluate the Tolerability, Safety, Pharmacokinetics and Pharmacodynamics of TQA3810 TabletsNo drug interventionstreatment1completed
NCT02991638
Efficacy and Safety of Ibrutinib in Patients With CLL and Other Indolent B-cell Lymphomas Who Are Chronic Hepatitis B Virus Carriers or Occult Hepatitis B Virus Carrierstreatment3unknown_status
NCT03801538
The Optimizing Treatment of Peginterferon Alpha in Chronic Hepatitis B Patients With Low Level HBsAgNo drug interventionstreatment4unknown_status
NCT01320943
Stopping TDF Treatment After Long Term Virologic Suppression in HBeAg-negative CHBtreatment4completed
NCT03210506
The Changes of Cytokines During Antiviral TherapytreatmentNot Availableunknown_status
NCT04135235
Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis BNo drug interventionsNot AvailableNot Availableunknown_status
NCT04030039
Cohort Study of Clinical Outcomes in Chronic HBV Infection Patients With Low HBsAg Under Unplanned InterventionNo drug interventionsNot AvailableNot Availableunknown_status
NCT04638439
The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D Infectiontreatment1unknown_status
NCT03329820
Quality of Life and Health Utility of Patients With CHB InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT05355467
Efficacy and Safety of Ricovir® in Maintaining Durability of Viral Response in Chronic Hepatitis B Patients Who Have Been Treated With Viread® and Have Undetectable HBV DNA in Serumtreatment4completed
NCT03587467
Study on Gut Microbiota in Chronic HBV Infected PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03208998
The Changes of Natural Killer Cells Frequency and Function During Antiviral Therapytreatment4unknown_status
NCT03209011
The Changes of CD4+T Cells Frequency and Function During Antiviral Therapytreatment4unknown_status
NCT03210493
The Changes of Treg Cells Frequency and Function During Antiviral TherapytreatmentNot Availableunknown_status
NCT03209037
The Changes of CD8+T Cells Frequency and Function During Antiviral Therapytreatment4unknown_status
NCT03210467
The Changes of Plasmacytoid Dendritic Cells Frequency and Function During Antiviral TherapyNo drug interventionsNot AvailableNot Availableunknown_status