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Displaying results 2021 - 2030 of 10000 in total
  1. Drug

    Mechlorethamine

    go.drugbank.com/drugs/DB00888
    ApprovedInvestigational

    A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. … ) in patients who have received prior skin-directed therapy.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: β,β'-dichlorodiethyl-N-methylamine, N-methyl-bis(2-chloroethyl)amine
  2. Drug

    Benzoin resin

    go.drugbank.com/drugs/DB11222
    Approved

    While benzoin resin is used as a common ingredient in incense-making and perfumery, it is also used clinically as a mild antiseptic agent in over-the-counter products to clean sores, cuts, wounds, and … Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus _Styrax_.

    Mixtures: Skin-E-dip Ont, Blistex Kank-A
  3. Drug

    Trifarotene

    go.drugbank.com/drugs/DB12808
    ApprovedInvestigational

    Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. … to vitamin A and are analogous only in function.

    Categories: Retinoids for Topical Use in Acne, Cytochrome P-450 SubstratesProducts: AKLIEF CREAM 50MCG/G
  4. Drug

    Phleum pratense pollen

    go.drugbank.com/drugs/DB10394
    ApprovedInvestigational

    Phleum pratense pollen allergenic extract is used in allergenic testing.

    Mixtures: ORALAIR 100 IR + 300 IR Sublingualtabletten, ORALAIR 100 IR + 300 IR SublingualtablettenProducts: GRAZAX 75.000 SQ-T ORAL LIYOFILIZAT 100 TABLET, GRAZAX 75.000 SQ-T ORAL LIYOFILIZAT TABLET, 30 ADET
  5. Pathway

    Tocainide Sodium Channel Cardiac Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0126519
    Drug action

    In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. … Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias.

    Drugs: Tocainide · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  6. Drug

    Canagliflozin

    go.drugbank.com/drugs/DB08907
    ApprovedInvestigational

    It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type … Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise

    Mixtures: VOKANAMET ® TM_TABLETAS RECUBIERTAS 150/1000 MGCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  7. Drug

    Bromothalonil

    go.drugbank.com/drugs/DB14199
    Approved

    It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy [A34322]. … Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Bromo-2-(bromomethyl) glutaronitrile, 2-Bromo-2-(bromomethyl) pentanedinitrile
  8. Drug

    Dipivefrin

    go.drugbank.com/drugs/DB00449
    ApprovedWithdrawn

    Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).

    Categories: Sympathomimetics in Glaucoma Therapy, Adrenergic alpha-1 Receptor AgonistsSynonyms: 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol, (±)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
  9. Drug

    Technetium Tc-99m disofenin

    go.drugbank.com/drugs/DB09164
    ApprovedWithdrawn

    It is available as an intravenous injection in a preparation kit under the name Hepatolite. … Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Anthoxanthum odoratum pollen

    go.drugbank.com/drugs/DB10404
    Approved

    Anthoxanthum odoratum pollen is the pollen of the Anthoxanthum odoratum plant. Anthoxanthum odoratum pollen is mainly used in allergenic testing.

    Mixtures: Oralair 300 IR, Oralair 300 IR