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Nicorandil
go.drugbank.com/drugs/DB09220ApprovedInvestigationalWithdrawnNicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. … It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels.
International brands: K-CorTakayasu Arteritis
go.drugbank.com/conditions/DBCOND0000704Drugs: PrednisoneSynonyms: Sclerosing aortitis AND arteritis, Idiopathic medial aortopathy AND arteriopathyEtonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigational[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Mixtures: Etonogestrel and Ethinyl Estradiol, Etonogestrel and Ethinyl Estradiol VaginalCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemBelumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigational[L34754] In July 2022, Belumosudil was approved by Health Canada under the brand name RHOLISTIQ to treat the same condition in adult and pediatric patients 12 years or older.[L42925] … [A236644,L34759] Belumosudil was first approved by the FDA in July 2021, under the brand name Rezurock, for the treatment of chronic GVHD in patients who have tried and failed at least two prior lines
Categories: Antineoplastic and Immunomodulating AgentsRitlecitinib
go.drugbank.com/drugs/DB14924ApprovedInvestigationalIn June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further approved by the EMA in September 2023. … This makes ritlecitinib a highly selective and irreversible JAK3 inhibitor.
Categories: Antineoplastic and Immunomodulating AgentsPraziquantel
go.drugbank.com/drugs/DB01058ApprovedInvestigationalVet approved[A263201] The efficacy of praziquantel in treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat a child) makes it an integral to WHO's plan to eliminate schistosomiasis by 2030 … Praziquantel is a pyrazino-isoquinolein derivative from the thioxantonic group used as a broad anthelmintic spectrum.
Categories: Quinoline Derivatives and Related Substances, Antiparasitic Products, Insecticides and RepellentsEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedIt is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. … Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties.
Mixtures: ETOFAM 400MG/20MG FİLM KAPLI TABLET, 20 ADET, ETOPLUS 400MG/8MG/20MG FİLM KAPLI TABLET, 14 ADETCategories: Acetic Acid Derivatives and Related Substances, Antiinflammatory and Antirheumatic ProductsClodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approved[A203111] Clodronic acid is not FDA approved, but is approved in Canada.[L13910] … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid].
Categories: Drugs Affecting Bone Structure and MineralizationBerotralstat
go.drugbank.com/drugs/DB15982ApprovedInvestigational[A225106] Berotralstat was first approved by the FDA on December 3, 2020, as the first once-daily oral therapy to prevent angioedema attacks of HAE in adults and pediatric patients 12 years and older. … [L41960] In December 2025, the FDA expanded Berotralstat pediatric use with approval of an oral pellet formulation for prophylaxis in children with HAE aged 2 and older.[L54793,L54798]
Categories: Blood and Blood Forming Organs