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CX-052075
go.drugbank.com/drugs/DB31655Approved[L53413,A274083] mNEXSPIKE was approved by the US FDA in June 2025 for use in patients who have been previously vaccinated with any COVID-19 vaccine and who are at a higher risk of severe outcomes from … [L53408,L53423] The original approval was formulated with the JN.1 strain ([mRNA-1283]), but was ultimately updated to the sublineage LP.8.1.[L54586]
Lofexidine
go.drugbank.com/drugs/DB04948ApprovedInvestigational[T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018.[L2794] … [A33084] It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of hypertension than clonidine.
Daptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil samples from Mount Ararat in Turkey. … [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name CUBICIN® by Cubist Pharmaceuticals LLC (Merck & Co.).[L32534]
Categories: Amino Acids, Peptides, and ProteinsGatifloxacin
go.drugbank.com/drugs/DB01044ApprovedInvestigationalWithdrawnGatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. … Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. It is also available as eye drops under the brand name Zymar® marketed by Allergan.
Mixtures: Pred-Gati-Brom, Pred-Gati-BromL-Glutamine
go.drugbank.com/drugs/DB00130ApprovedInvestigationalNutraceuticalA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. … An oral formulation of L-glutamine was approved by the FDA in July 2017 for use in sickle cell disease [L892]. This oral formulation is marketed under the tradename Endari by Emmaus Medical.
Categories: Amino Acids and Derivatives, Alimentary Tract and MetabolismZoledronic acid
go.drugbank.com/drugs/DB00399ApprovedInvestigational[A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. … Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid].
Categories: Drugs Affecting Bone Structure and Mineralization, zoledronic acid, calcium and colecalciferol, sequentialProducts: ZOLEDRONSAEURE F K 4MG/5ML, ACLASTA 5MGEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedIt is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. … Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties.
Mixtures: ETOFAM 400MG/20MG FİLM KAPLI TABLET, 20 ADET, ETOPLUS 400MG/8MG/20MG FİLM KAPLI TABLET, 14 ADETCategories: Acetic Acid Derivatives and Related Substances, Antiinflammatory and Antirheumatic ProductsOdevixibat
go.drugbank.com/drugs/DB16261ApprovedInvestigationalOdevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC … [A236808] Odevixibat was granted FDA and Health Canada approval on 20 July 2021 and 13 November 2023 respectively.[L34793,L49535]
Categories: Bile and Liver Therapy, Alimentary Tract and Metabolism