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Valrubicin
go.drugbank.com/drugs/DB00385ApprovedIt is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder. … Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR.
Categories: Topoisomerase II InhibitorsSynonyms: (8S, 10S)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione 8²-valerate, 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino]hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl pentanoateTroglitazone
go.drugbank.com/drugs/DB00197ApprovedWithdrawnTroglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by [pioglitazone] and [rosiglitazone].
Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP2B6 InducersRibavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalas an adjunct therapy to various first-line and second-line combination therapies recommended for each genotypes. … The inclusion of ribavirin in the combination therapies depend on individual patient's profile, for example if HCV genotype 3 patient has a Y93H genetic variant and compensated cirrhosis.
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules)Categories: Antivirals for treatment of HCV infections, Treatments for Hepatitis CCalcium ascorbate
go.drugbank.com/drugs/DB14483ApprovedNutraceuticalMixtures: Vc II, Procosa IICategories: Compounds used in a research, industrial, or household setting, Vitamin C and analoguesIophendylate
go.drugbank.com/drugs/DB01187ApprovedIt next appeared on the world scene for high volume (12-15cc), routine use, in diagnosing disc herniations. A number of clinicians have published on the dangers of oil myelography. … In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified Iophendylate as causing chemical meningitis in 30 patients where "space-displacing masses within the
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsSynonyms: Ethyl 10-(p-iodophenyl)-undecanoate, Ethyl 10-(p-iodophenyl)undecylatePipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnHowever, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: NEUROVAN®, PIPORTIL ® L-4SOLUCION INYECTABLE AL 2.5% (100 MG).Buspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigationalIt has also been used as a second-line therapy for unipolar depression when the use of selective serotonin reuptake inhibitors (SSRIs) is deemed clinically inadequate or inappropriate. … Due to these characteristics, buspirone been termed 'anxioselective'.[A180985] First synthesized in 1968 then patented in 1975,[L7375] it is commonly marketed under the brand name Buspar®.
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dioneMethscopolamine
go.drugbank.com/drugs/DB11315ApprovedMethscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. … The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Mixtures: AlleRx-D, Allergy DN IICitric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedA key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. … Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.
Mixtures: E-Z-gas II, E-Z-GAS II GRANULESCategories: Compounds used in a research, industrial, or household setting, Disinfectants (For Agents Used on Object)