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Displaying results 2081 - 2090 of 10000 in total
  1. Drug

    Travoprost

    go.drugbank.com/drugs/DB00287
    ApprovedInvestigational

    risk for developing off-target side effects. … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist.

    Mixtures: DuoTrav Eye Drops, Solution (5mg/40mcg) per mL, TRAVAPRESS DUO 40 MCG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADETSynonyms: isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(α,α,α-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoate, ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)OXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOATE
  2. Drug

    Lanadelumab

    go.drugbank.com/drugs/DB14597
    ApprovedInvestigational

    Lanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection. … [L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells.

    Products: TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET
  3. Drug

    Entrectinib

    go.drugbank.com/drugs/DB11986
    ApprovedInvestigational

    [L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. … [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval based on early trial data.

    Synonyms: N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamideCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  4. Pathway

    Acylcarnitine (10E)-8-Hydroxydodec-10-enoylcarnitine

    smpdb.ca/view/SMP0124017
    Metabolic

    (10E)-8-Hydroxydodec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10E)-8-hydroxydodec-10-enoyl-CoA reacts with L-carnitine to form (10E)-8-hydroxydodec-10-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  5. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. … Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSynonyms: 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine, 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine
  6. Drug

    Somatostatin

    go.drugbank.com/drugs/DB09099
    ApprovedInvestigationalWithdrawn

    Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues [T28] that regulates the endocrine system. … Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 (SST-28), an extended SST-14 sequence to the N-terminus [A20384].

    Synonyms: Synthetic somatostatin-14Products: STILAMIN 3000 FOR INJECTION 3 mg/ampoule, SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPUL
  7. Drug

    Amino acids

    go.drugbank.com/drugs/DB09393
    Investigational

    Mixture of amino acids ; used for parenteral nutrition in infants.

    Mixtures: NUTRINEAL PERITON DIYALIZ ÇÖZELTİSİ, ÇIFTLI TORBA, MINI KAPAKLI, 2000 ML, Clinimix 3 % G-E - InfusionsbeutelCategories: Solutions for Parenteral Nutrition
  8. Drug

    Pancuronium

    go.drugbank.com/drugs/DB01337
    Approved

    A bis-quaternary steroid that is a competitive nicotinic antagonist. … As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.

    Products: BROMURO DE PANCURONIO 4 MG/2 ML, BROMURO DE PANCURONIO 2 MG/ML
  9. Drug

    Quinidine barbiturate

    go.drugbank.com/drugs/DB01346
    Approved

    A papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909)

    Products: NATISEDINE 100 MG TABLET, 20 ADET
  10. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    A high-concentration, citrate-free formulation of Cyltezo® (adalimumab-adbm), a biosimilar to Humira®, was approved by the FDA in May 2024 for the treatment of multiple chronic inflammatory diseases. … This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered doses.[A39983] Several biosimilars to adalimumab.

    Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: AMGEVITA 40 mg/0.8 ml solution for injection in pre-filled syringe, AMGEVITA 20 mg/0.4 ml solution for injection in pre-filled syringe